Protein

Experimentally validated
View in Explore
UniProt accession
A0A2K9VGS2 [UniProt]
Protein name
Probable tail spike protein
RBP type
TF
Evidence GenBank
Probability 1,00
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect
Probability 0,91
TSP
Evidence RBPdetect2
Probability 0,96
TSP
Evidence DepoCatalog
Probability 1,00
Seq2Symm
C3 confidence 0,999
C3 0,999
C6 0,002
D3 0,002
Predicted homo-oligomer symmetry (Seq2Symm, per-class probabilities; C1 = monomer, C2 = dimer, C3 = trimer).
Protein sequence
MDQDTKTIIQYPTSGDEYDIPFDYLSRKFVRVSLVSNTQRVLLDNITDYRYVSRTRVKLLVSTDGYSRVEIRRFTSASEMVVDFSDGSVLRATDLNVSALQSAHIAEEARDLFSTSLSIGQLSYFDAKGLQIKNVAAGVDNTDAVTVQQLNKIIADVVTTIPDSVADNIRGLWARVLGDIGITLVDGSFETGATITTRTQALWSISGRKCYTWAGALPKVVPENSTPESTGGISETAWVDSSSKALGVLLAGPSGAERVGLKQGGTVQDAINWLTFDSFDIVKDGSKDVTADIMAACVVANDLGLDIKQNDGTYLVSGNPVWPVYNSLDLNGVTLKLAAGFTGYFALTQKDSTTVYGPTSPIVQAINAAGGRTAGSGVLEGLVNSTELNGKFLFMEGADVLYYSRGTAKYWWTNTYLSNRGKLSDNLKYGVSAITKITAVTPRTKIVYYRLPNLDFGNGPANNGVIRVLNNTRFIMQGGSISNRPLKDVSKSPVIISLNYCAAFKAYDFFDPYPAFAVDSNNSLVYSYTLNFNDIADAVFENFNSQGYGWGVVGGQRSTNITYRDCNLNRVDMHNPYMGYLKVLDTRLGTWGINASGMGDMYLERVTVDLDDSAHGGHREHEGIINARGDFGGFHDGGLYIKDLTIVGEASAFEATSGHPVALVSAYSFNASLAYIPESSPVTPWGFKEVIVEGLHCPFKRTGRRFNSIISAPSIQFTVYHPMRVKLEDCNFNSTAFEKFDLRGWRVTPYNPSKVGIANTLAFRPTNFVDVKDCSMVGLEFTRPTSAYDYSNFDVNLVNVKNVEEHSLSPFTLYTNQCGRYNLVGCGLQQIVDKSMTSGERANRRSTFSVTGGTWNSLSGNPTDITYGNGYDIPVVATGVMFVGPYSQTEVTGANLNVAEFVQASGCKFLSSGPTYIQPLLWSGAGGPTGASANFNVARGNTLGLNISAVNGETSQVIAATLVIPQGFSTGPAAGTTYGFAVEKNINYQLGLNARSLKANVGLVRCSDTITGVYLNA
Physico‐chemical
properties
protein length:1017 AA
molecular weight: 109986,19210 Da
isoelectric point:5,66306
aromaticity:0,10226
hydropathy:-0,09872

Domains

View on InterPro
Domain architecture
A0A2K9VGS2
1 1017 aa
ATT 6–126 · STR 127–161 · ATT 182–241 ·
ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped
Proteins with similar domain architecture

Tail Spike Domain Segmentation

Segmented into three structural domains: N-terminal, central, and C-terminal.

Domain layout
A0A2K9VGS2
1 1017 aa
Domain Start End Length (AA) Confidence
N-terminal 1 289 289 0,9946
Central domain 290 919 631 0,9932
C-terminal 920 1017 97 0,9241
N-terminal Central domain C-terminal

View these domains on the 3D structure via the Color by → Tail spike option in the Tertiary structure section below.

Taxonomy

Phage
Klebsiella phage SH-Kp 152410 [NCBI] · taxon 2066504
Uroviricota Caudoviricetes Autographivirales Studiervirinae Przondovirus
Host
Klebsiella pneumoniae [NCBI] · taxon 573
cellular organisms Bacteria Pseudomonadati Pseudomonadota Gammaproteobacteria Enterobacterales

Coding sequence (CDS)

No CDS data available.

Genome Context

Gene Ontology

Description Category Evidence (source)
GO:0019867 outer membrane Cellular Component IEA:InterPro (UniProt)
GO:0098015 virus tail Cellular Component IEA:UniProtKB-KW (UniProt)
GO:0098671 adhesion receptor-mediated virion attachment to host cell Biological Process IEA:UniProtKB-KW (UniProt)
GO:0098994 symbiont entry into host cell via disruption of host cell envelope Biological Process IEA:UniProtKB-KW (UniProt)
GO:0098996 symbiont entry into host cell via disruption of host cell glycocalyx Biological Process IEA:UniProtKB-KW (UniProt)

Tertiary structure

A0A2K9VGS2
1 / 4
Structure ID
Source
Method
Resolution
Oligomeric state

Experimental validation

Experimentally validated

A wet-lab result is recorded for this protein, or for its sequence: a solved structure, an experimental GO annotation, a UniProt ECO:0000269 assertion, or a GenBank /experiment= qualifier.

Tier Source Assay Claim Reference
Experimentally validated PDB
8X8M
 structure:EM — ECO:0000006
Experimentally validated PDB
8X8O
 structure:EM — ECO:0000006
Experimentally validated UniProt
A0A2K9VGS2
 protein_existence:evidence_at_protein_level 1: Evidence at protein level —
Literature-linked PubMed
38513899
 literature_xref — PMID 38513899

Rows marked “Validated by sequence identity” come from a different entry carrying the same sequence — the experiment was not performed on this protein.

Literature

Title Authors Date PMID Source
— — 38513899 PubMed