Protein

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UniProt accession
Q54699 [UniProt]
Protein name
Hyaluronoglucosaminidase
RBP type
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect2
Probability 0,96
Protein sequence
MSENIPLRVQFKRMKAAEWARSDVILLESEIGFETDTGFARAGDGHNRFSDLGYISPLDYNLLTNKPNIDGLATKVETAQKLQQKADKETVYTKAESKQELDKKLNLKGGVMTGQLKFKPAATVAYSSSTGGAVNIDLSSTRGAGVVVYSDNDTSDGPLMSLRTGKETFNQSALFVDYKGTTNAVNIAMRHATTPNFSSALNITSGNENGSAMQLRGSEKALGTLKITHENPSIGADYDKNAARYPLILSKRQNGAGTAAQGIYINSTSGTTGKLLRIRNLSDDKFYVKSDGGFYAKETSQIDGNLKLKDPTANDHAATKAYVDKAISELKKLILKK
Physico‐chemical
properties
protein length:337 AA
molecular weight: 36452,58130 Da
isoelectric point:9,27566
aromaticity:0,06825
hydropathy:-0,51543

Domains

Domains [InterPro]
SSF69349
STR
7–335
SSF69349
IPR041352
ATT
9–45
IPR041352 IPR009860
Q54699
1 337
Architecture
ATT
STR
ATT 7-45 | STR 46-335 |
Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout
N-terminal
Central
C-terminal
Q54699
1 337
Domain Start End Length (AA) Confidence
N-terminal 1 111 111 0,9861
Central domain 112 310 200 0,1270
C-terminal 311 337 26 0,9896
Legend: N-terminal Central domain C-terminal
3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring
N-terminal
1-111
Central
112-310
C-terminal
311-337

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptococcus pyogenes phage H10403
[NCBI] 		86065 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
AAA86895.1 [NCBI]
Genbank nucleotide accession
U28144 [NCBI]
CDS location
range 106 -> 1119
strand +
CDS
ATGAGTGAAAATATACCGCTGCGAGTCCAATTTAAGCGCATGAAAGCCGCCGAGTGGGCTCGTAGTGATGTCATCTTACTGGAGAGCGAGATAGGCTTTGAGACAGACACAGGTTTTGCCAGAGCAGGTGATGGGCACAATCGATTTAGTGACCTTGGATACATTAGTCCACTCGATTACAATCTACTGACTAACAAGCCAAATATTGATGGATTAGCGACAAAAGTCGAGACCGCTCAGAAACTACAACAAAAAGCAGATAAAGAGACCGTCTATACAAAAGCTGAATCGAAGCAAGAGCTTGACAAGAAATTAAATCTCAAAGGTGGCGTTATGACAGGTCAACTAAAATTTAAGCCAGCCGCCACTGTTGCTTATTCCTCGTCAACGGGTGGAGCGGTCAATATTGACTTGTCGTCTACCAGAGGTGCTGGTGTTGTTGTCTATTCTGACAATGATACCAGTGATGGGCCGTTAATGAGCTTGCGGACGGGTAAAGAGACCTTTAATCAATCGGCGCTTTTTGTCGACTATAAGGGGACAACAAATGCCGTTAATATTGCGATGCGTCACGCAACCACCCCCAATTTTTCATCGGCGCTTAATATTACTAGCGGCAATGAAAATGGTAGTGCAATGCAGCTACGAGGGTCAGAAAAAGCGCTAGGAACGCTAAAAATTACTCATGAGAACCCAAGTATTGGAGCGGATTATGATAAAAATGCGGCACGTTATCCATTGATATTGTCAAAAAGACAAAACGGTGCAGGAACAGCCGCTCAGGGAATCTACATTAACTCAACCTCAGGCACGACAGGGAAGTTGCTTAGGATTAGAAACCTTAGTGATGATAAGTTCTACGTCAAGTCTGACGGTGGTTTTTATGCCAAGGAAACTTCGCAGATTGATGGCAACCTGAAACTCAAGGACCCCACAGCGAATGATCATGCGGCAACCAAAGCTTATGTAGATAAAGCAATTTCTGAGTTAAAAAAACTCATACTAAAAAAATAG

Genome Context

Genome Context

Gene Ontology

Description Category Evidence (source)
GO:0044423 virion component Cellular Component IEA:UniProtKB-KW (UniProt)
GO:0004415 hyalurononglucosaminidase activity Molecular Function IEA:UniProtKB-EC (UniProt)
GO:0045227 capsule polysaccharide biosynthetic process Biological Process IEA:InterPro (UniProt)
GO:0098994 symbiont entry into host cell via disruption of host cell envelope Biological Process IEA:UniProtKB-KW (UniProt)
GO:0098996 symbiont entry into host cell via disruption of host cell glycocalyx Biological Process IEA:UniProtKB-KW (UniProt)

Tertiary structure

PDB ID
dcfef7686e9546d41aff082df646bd2c91f4db16e0a1af040a8d0cda3732782c
ESMFold
Source ESMFold
Method ESMFold
Resolution 0,7660
Oligomeric State monomer
Download PDB
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50

Literature

Title Authors Date PMID Source
— — 7622224 PubMed