Protein

View in Explore
UniProt accession
Q54699 [UniProt]
Protein name
Hyaluronoglucosaminidase
RBP type
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect2
Probability 0,90
Protein sequence
MSENIPLRVQFKRMKAAEWARSDVILLESEIGFETDTGFARAGDGHNRFSDLGYISPLDYNLLTNKPNIDGLATKVETAQKLQQKADKETVYTKAESKQELDKKLNLKGGVMTGQLKFKPAATVAYSSSTGGAVNIDLSSTRGAGVVVYSDNDTSDGPLMSLRTGKETFNQSALFVDYKGTTNAVNIAMRHATTPNFSSALNITSGNENGSAMQLRGSEKALGTLKITHENPSIGADYDKNAARYPLILSKRQNGAGTAAQGIYINSTSGTTGKLLRIRNLSDDKFYVKSDGGFYAKETSQIDGNLKLKDPTANDHAATKAYVDKAISELKKLILKK
Physico‐chemical
properties
protein length:337 AA
molecular weight: 36452,58130 Da
isoelectric point:9,27566
aromaticity:0,06825
hydropathy:-0,51543

Domains

View on InterPro
Domain architecture
Q54699
1 337 aa
ATT 7–45 · STR 46–335 ·
ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped
Proteins with similar domain architecture

Tail Spike Domain Segmentation

Segmented into three structural domains: N-terminal, central, and C-terminal.

Domain layout
Q54699
1 337 aa
Domain Start End Length (AA) Confidence
N-terminal 1 111 111 0,9861
Central domain 112 310 200 0,1270
C-terminal 311 337 26 0,9896
N-terminal Central domain C-terminal

View these domains on the 3D structure via the Color by → Tail spike option in the Tertiary structure section below.

Taxonomy

Phage
Streptococcus pyogenes phage H10403 [NCBI] · taxon 86065
No lineage information
Host No host information

Coding sequence (CDS)

Genbank protein accession
AAA86895.1 [NCBI]
Genbank nucleotide accession
U28144 [NCBI]
CDS location
range 106 -> 1119
strand +
CDS
ATGAGTGAAAATATACCGCTGCGAGTCCAATTTAAGCGCATGAAAGCCGCCGAGTGGGCTCGTAGTGATGTCATCTTACTGGAGAGCGAGATAGGCTTTGAGACAGACACAGGTTTTGCCAGAGCAGGTGATGGGCACAATCGATTTAGTGACCTTGGATACATTAGTCCACTCGATTACAATCTACTGACTAACAAGCCAAATATTGATGGATTAGCGACAAAAGTCGAGACCGCTCAGAAACTACAACAAAAAGCAGATAAAGAGACCGTCTATACAAAAGCTGAATCGAAGCAAGAGCTTGACAAGAAATTAAATCTCAAAGGTGGCGTTATGACAGGTCAACTAAAATTTAAGCCAGCCGCCACTGTTGCTTATTCCTCGTCAACGGGTGGAGCGGTCAATATTGACTTGTCGTCTACCAGAGGTGCTGGTGTTGTTGTCTATTCTGACAATGATACCAGTGATGGGCCGTTAATGAGCTTGCGGACGGGTAAAGAGACCTTTAATCAATCGGCGCTTTTTGTCGACTATAAGGGGACAACAAATGCCGTTAATATTGCGATGCGTCACGCAACCACCCCCAATTTTTCATCGGCGCTTAATATTACTAGCGGCAATGAAAATGGTAGTGCAATGCAGCTACGAGGGTCAGAAAAAGCGCTAGGAACGCTAAAAATTACTCATGAGAACCCAAGTATTGGAGCGGATTATGATAAAAATGCGGCACGTTATCCATTGATATTGTCAAAAAGACAAAACGGTGCAGGAACAGCCGCTCAGGGAATCTACATTAACTCAACCTCAGGCACGACAGGGAAGTTGCTTAGGATTAGAAACCTTAGTGATGATAAGTTCTACGTCAAGTCTGACGGTGGTTTTTATGCCAAGGAAACTTCGCAGATTGATGGCAACCTGAAACTCAAGGACCCCACAGCGAATGATCATGCGGCAACCAAAGCTTATGTAGATAAAGCAATTTCTGAGTTAAAAAAACTCATACTAAAAAAATAG

Genome Context

Gene Ontology

Description Category Evidence (source)
GO:0044423 virion component Cellular Component IEA:UniProtKB-KW (UniProt)
GO:0004415 hyalurononglucosaminidase activity Molecular Function IEA:UniProtKB-EC (UniProt)
GO:0045227 capsule polysaccharide biosynthetic process Biological Process IEA:InterPro (UniProt)
GO:0098994 symbiont entry into host cell via disruption of host cell envelope Biological Process IEA:UniProtKB-KW (UniProt)
GO:0098996 symbiont entry into host cell via disruption of host cell glycocalyx Biological Process IEA:UniProtKB-KW (UniProt)

Tertiary structure

Q54699
ESMFold structure
Source ESMFold
pLDDT 76.6
Oligomeric state monomer
Download structure

Literature

Title Authors Date PMID Source
— — 7622224 PubMed