Phage RBP Database

Genbank accession

XQQ52602.1 [GenBank]

Protein name

tail spike protein

RBP type

TF

Evidence GenBank

Probability 1,00

TSP

Evidence DepoScope

Probability 1,00

TSP

Evidence RBPdetect

Probability 0,88

TF

Evidence RBPdetect2

Probability 0,38

Seq2Symm

C3 confidence 0,999 truncated

C3	0,999
C4	0,002
C1	0,001

Predicted homo-oligomer symmetry (Seq2Symm, per-class probabilities; C1 = monomer, C2 = dimer, C3 = trimer).

Protein sequence

MNAHTPFDANQDWTNPYCHNSSNDQMVDALLGNAYHVVRTVYCNLGNLKLLYDFLNQYGMVIGVNSEEELKALSTQVKYSRIYGFSRAGDRQVTDYLYVEGDRTGIIPDDSEATGSWITVATSGSNGGGTSSSEGAYIPWVYSNGSATGGETTINVPDGTVGVPFIIVNGDMQYVGRGFEFNVDSLSVTLAQPLEEGDEVVFLLTGVPAVPDNPNINDWIQINWLYNNGAAVGGEQVIAIPYTFQSIPAVYKNGLRLYKGLTTESYTADPDNQRIFLTEPLTTNDRLIVQIGGEARVLEATDRTLQEVARAANVKDSEVILSTNTVQSLNNKKVIYNPDNQQIYVIPELPTNAYISSVVGNILTYTPGNIQVELLTKKETDQNTLWRNQGDVRGWGVKGDAVHDDTVALTNVLNDTPVGQKINGNGKTYKVTSLPDISRFVNTRFVYERIPGQPLYYASEEFVQGELFKITDTPYYNAWPQDKAFVYDDVIYCPFMASDRHGVSRLHVSWVRSGDDGQTWTTPEWLTDLHPDYPTVNYHCMSMGVMRNRLFAMIETRTLASNALVTCEIWDRPMSRNYHPTGGITKAANQPVAVITIPDHGLFAGDFVNFSNSGVTGVSGNMTVTSVIDRNTFTVTTPNQQESDQNNSTKVWHMGTSFHQSPWRKTNLGLIPMVTEVHSFTAINNDSFMMGYHQGDAAPREVGMLYFPDAFNNPGHYIKRRIPAEYEPDAAEPCVKYFDGVLYVVTRGTRSDRLGSSLHRSNDLGISWQSLRFPNNVHHSTLPFAKVGNELILFGTERADNEWEANAPDQRYFSSYPRTFYTRVNLDTWNLDNTQWVNITDQIYQGGIVNSGVGVGSVVVKDSYIYYMFGGEDHLNPWTYGDNSSKDPFKSDGHPSDLYCYKMKIGSDNRVSRDFRYGAVPDRAVPVFFDTNGIRTVPAPMEFTGDLGLGHVTLRASTSSNIRSEVLMEGEYGFIGKSVPTNNPAGQRIIFCGGDGTSSSTGAQITLYGASNTASRRIVYNGNEHLFQGADVKPYNDNVIALGGPRNRFTTAYLGSNPIVTSNGEKKTEPVVFDDAFLDAWGDVHYIMYQWLDAVQLKGNDARIHFGVIAQQIRDVFIAHGLMDENSTNCRYAVLCYDKYPRMTDTVFSHNEIVEHTDEEGNVTTTEEPVYTEVVIHEEGEEWGVRPDGIFFAEAAYQRRKLERIEARLSALEQK

Physico‐chemical properties

protein length:	1215 AA
molecular weight:	135421,99720 Da
isoelectric point:	4,98259
aromaticity:	0,10782
hydropathy:	-0,39572

Domain architecture

XQQ52602.1

1 1215 aa

ATT 296–380 · ATT 392–463 · STR 464–1061 · CHP 1062–1074 · RBD 1075–1126 · CHP 1127–1185 · RBD 1186–1215

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

InterPro domains

G3DSA:3.30.2020.50
ATT

G3DSA:3.30.2020.50 G3DSA:3.30.750.60 IPR024428 IPR024430 cd10144

IPR036278
STR

IPR036278 SSF69349 IPR030392

IPR024429
ENZ

IPR024429 IPR001724 IPR001724 IPR023366 IPR001724 IPR001724 IPR001724 IPR044914 IPR030392 G3DSA:3.30.2460.10 G3DSA:1.20.5.100

G3DSA:2.120.10.10
STR

G3DSA:2.120.10.10 IPR001724 IPR001724 G3DSA:1.20.5.1240 Coil

IPR024427
ENZ

IPR024427

IPR001724
Unmapped

IPR001724

XQQ52602.1

11215 aa

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

Novel HMM domains (de novo, PhaRBP-HMM)

Experimental de novo families on regions without InterPro annotation. Separate from the InterPro architecture above.

DC_0041
STR

DC_0041

XQQ52602.1

11215 aa

InterPro domain annotations

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
G3DSA:3.30.2020.50	ATT	G3DSA:3.30.2020.50	296	380	Merged direct domain	G3DSA:3.30.2020.50	N-terminal	Low	Positional only	289 proteins / 289 hits
G3DSA:3.30.750.60	ATT	G3DSA:3.30.750.60	392	463	Merged direct domain	G3DSA:3.30.750.60	N-terminal	Low	Positional only	2 proteins / 2 hits
IPR036278	STR	IPR036278	396	911	Merged direct domain	Sialidase superfamily	Central	Low	Positional only	56 proteins / 56 hits
IPR024429	ENZ	DC_0802	398	463	InterPro cluster	Endosialidase, N-terminal extension domain	N-terminal	High	Text match	84 proteins / 84 hits
IPR024428	ENZ	DC_0114	464	905	InterPro cluster	Endosialidase, beta-propeller domain	Central	High	Text match	92 proteins / 92 hits
IPR001724	Unmapped	-	465	489	InterPro	Glycosyl hydrolase 58	-	-	-	-
G3DSA:2.120.10.10	STR	G3DSA:2.120.10.10	465	905	Merged direct domain	G3DSA:2.120.10.10	Central	Low	Positional only	42 proteins / 42 hits
IPR001724	Unmapped	-	530	558	InterPro	Glycosyl hydrolase 58	-	-	-	-
IPR023366	STR	IPR023366	575	661	Merged direct domain	ATP synthase subunit alpha, N-terminal domain-like superfamily	Central	Low	Positional only	44 proteins / 44 hits
IPR024427	ENZ	DC_0382	575	657	InterPro cluster	Endosialidase, beta-barrel domain	Central	High	Text match	86 proteins / 86 hits
IPR001724	Unmapped	-	649	672	InterPro	Glycosyl hydrolase 58	-	-	-	-
IPR001724	Unmapped	-	719	745	InterPro	Glycosyl hydrolase 58	-	-	-	-
IPR001724	Unmapped	-	797	823	InterPro	Glycosyl hydrolase 58	-	-	-	-
IPR001724	Unmapped	-	853	877	InterPro	Glycosyl hydrolase 58	-	-	-	-
IPR024430	ENZ	DC_0521	908	1061	InterPro cluster	Endosialidase, C-terminal domain	C-terminal	High	Text match	95 proteins / 95 hits
IPR044914	RBD	IPR044914	908	1061	Merged direct domain	Endosialidase, C-terminal domain superfamily	C-terminal	Low	Positional only	39 proteins / 39 hits
SSF69349	STR	SSF69349	912	1061	Merged direct domain	SSF69349	Central	Low	Positional only	153 proteins / 153 hits
IPR001724	Unmapped	-	954	980	InterPro	Glycosyl hydrolase 58	-	-	-	-
IPR001724	Unmapped	-	986	1013	InterPro	Glycosyl hydrolase 58	-	-	-	-
cd10144	CHP	DC_0088	1062	1201	InterPro cluster	cd10144	C-terminal	High	Text match	3502 proteins / 3959 hits
IPR030392	CHP	DC_0088	1062	1215	InterPro cluster	Intramolecular chaperone auto-processing domain	C-terminal	High	Text match	3502 proteins / 3959 hits
IPR030392	CHP	DC_0088	1066	1122	InterPro cluster	Intramolecular chaperone auto-processing domain	C-terminal	High	Text match	3502 proteins / 3959 hits
G3DSA:1.20.5.1240	RBD	G3DSA:1.20.5.1240	1075	1126	Merged direct domain	G3DSA:1.20.5.1240	C-terminal	Low	Positional only	1 proteins / 1 hits
G3DSA:3.30.2460.10	Unmapped	-	1127	1185	Gene3D	None	-	-	-	-
G3DSA:1.20.5.100	RBD	G3DSA:1.20.5.100	1186	1215	Merged direct domain	G3DSA:1.20.5.100	C-terminal	Low	Positional only	8 proteins / 8 hits
Coil	Unmapped	-	1195	1215	Coils	Coil	-	-	-	-

Proteins with similar domain architecture

Segmented into three structural domains: N-terminal, central, and C-terminal.

Domain layout

XQQ52602.1

1 1215 aa

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	406	406	0,9963
Central domain	407	728	323	0,8890
C-terminal	729	1215	486	0,5771

N-terminal Central domain C-terminal

View these domains on the 3D structure via the Color by → Tail spike option in the Tertiary structure section below.

Phage

Escherichia phage PBM-3 [NCBI] · taxon 3402001

Viruses Duplodnaviria Heunggongvirae Uroviricota Caudoviricetes

Host

Escherichia sp. [NCBI] · taxon 1884818

cellular organisms Bacteria Pseudomonadati Pseudomonadota Gammaproteobacteria Enterobacterales

Genbank protein accession

XQQ52602.1 [NCBI]

Genbank nucleotide accession

PV053165.1 [NCBI]

CDS location

range 5901 -> 9548
strand +

CDS

ATGAACGCACATACCCCCTTTGATGCAAATCAGGATTGGACCAATCCATATTGTCATAACAGTTCCAATGACCAAATGGTGGATGCACTGCTTGGTAATGCTTACCATGTGGTTCGTACTGTGTACTGCAACCTGGGTAATCTTAAACTCCTGTATGATTTCCTGAACCAGTATGGGATGGTCATCGGTGTAAACTCTGAAGAGGAATTGAAGGCATTATCCACGCAGGTTAAATATTCCCGTATCTACGGTTTCTCCCGTGCAGGTGACCGGCAGGTAACTGATTACTTGTACGTAGAAGGTGATCGTACTGGCATCATCCCAGATGACTCAGAAGCAACTGGTTCGTGGATTACTGTTGCTACTTCTGGTTCCAATGGTGGTGGTACTTCTTCCAGTGAAGGTGCTTATATTCCTTGGGTATACAGCAATGGTTCTGCTACTGGTGGGGAAACCACAATCAACGTACCAGATGGTACGGTGGGTGTACCTTTCATTATTGTTAATGGCGACATGCAGTATGTAGGTCGTGGATTTGAGTTCAACGTAGACAGCCTGTCCGTAACTCTGGCCCAACCTTTAGAGGAAGGAGATGAAGTAGTATTCCTTCTGACTGGTGTTCCTGCTGTACCGGATAATCCTAACATTAATGACTGGATTCAGATCAATTGGTTGTACAACAATGGTGCTGCTGTAGGGGGTGAGCAGGTTATTGCTATTCCGTATACCTTCCAGTCTATTCCGGCTGTGTATAAGAATGGTCTTCGTTTGTATAAAGGATTAACTACTGAGTCTTATACTGCTGACCCAGATAACCAACGTATTTTTCTTACCGAACCACTGACAACCAATGATCGTTTGATAGTACAGATTGGTGGTGAAGCACGAGTATTGGAAGCAACAGATCGTACTCTACAGGAAGTGGCTCGTGCGGCTAATGTAAAAGATTCTGAGGTTATTCTCAGTACTAATACAGTACAATCCTTAAATAACAAAAAAGTTATTTATAATCCCGATAATCAGCAGATTTACGTTATTCCAGAATTACCAACTAATGCGTATATATCCAGCGTAGTTGGTAATATCCTTACATATACTCCAGGTAACATTCAGGTTGAGTTACTAACCAAAAAAGAAACTGACCAAAATACCCTATGGCGTAATCAGGGAGATGTCCGTGGTTGGGGTGTTAAAGGGGACGCTGTGCATGATGATACAGTAGCATTAACGAACGTATTAAACGACACACCAGTTGGACAAAAGATTAATGGCAATGGGAAGACATATAAGGTCACATCCTTGCCTGATATTAGTCGATTCGTCAACACTCGTTTTGTTTATGAGCGTATTCCTGGTCAGCCGCTTTATTATGCCTCTGAAGAATTTGTTCAGGGCGAGCTTTTCAAAATAACGGACACCCCTTATTACAATGCGTGGCCACAGGATAAAGCGTTCGTTTACGATGATGTTATTTACTGCCCGTTCATGGCTAGTGATAGACATGGGGTCAGCAGGCTGCATGTATCCTGGGTTCGTTCAGGGGATGACGGACAGACCTGGACAACGCCGGAATGGTTAACCGACCTACATCCTGATTACCCGACAGTTAACTACCACTGTATGAGTATGGGGGTGATGCGTAATCGTCTCTTTGCGATGATTGAGACACGTACTTTAGCATCTAACGCACTGGTGACCTGTGAGATATGGGACCGTCCTATGTCCCGTAATTACCATCCGACAGGTGGTATCACAAAAGCCGCTAATCAGCCTGTGGCTGTAATTACTATTCCTGACCATGGATTGTTTGCCGGAGATTTTGTTAACTTCTCGAACTCTGGGGTGACTGGTGTTTCGGGGAATATGACTGTAACTTCAGTTATTGACCGCAACACATTTACTGTCACCACGCCAAATCAACAGGAATCTGACCAAAATAACTCTACCAAAGTCTGGCATATGGGGACATCGTTCCACCAGTCACCTTGGCGTAAAACCAACCTTGGACTGATTCCCATGGTTACCGAGGTTCACAGTTTTACCGCCATCAATAATGATTCATTTATGATGGGATATCACCAGGGTGATGCTGCTCCACGTGAAGTTGGTATGCTGTATTTCCCGGATGCATTTAACAATCCTGGGCATTATATAAAACGACGTATCCCTGCTGAATATGAGCCAGATGCGGCAGAACCCTGTGTTAAATATTTTGACGGTGTTCTTTATGTTGTAACCCGTGGAACTCGGTCGGATCGTCTGGGTAGTTCACTACATCGTAGTAACGATTTGGGTATATCCTGGCAATCATTGAGGTTCCCGAATAATGTCCACCACTCCACCCTGCCATTCGCTAAGGTAGGAAACGAACTCATTCTTTTTGGAACAGAACGTGCGGACAACGAGTGGGAAGCAAACGCACCCGACCAGCGATATTTCAGTTCTTACCCGCGAACGTTTTACACACGAGTGAACTTAGACACCTGGAATCTGGATAATACTCAGTGGGTGAATATCACTGACCAGATATATCAGGGTGGCATTGTCAACTCTGGCGTTGGTGTTGGCTCAGTGGTTGTTAAGGATAGTTATATCTATTACATGTTCGGTGGGGAAGACCATCTGAACCCCTGGACATATGGAGATAACTCATCGAAAGACCCATTCAAATCAGATGGTCATCCATCAGATTTGTATTGCTACAAAATGAAGATTGGTTCAGACAATCGTGTTTCCAGGGATTTCAGATATGGTGCTGTACCTGACAGAGCTGTCCCCGTGTTTTTTGATACAAATGGGATTCGCACTGTTCCTGCTCCAATGGAATTTACAGGAGATTTGGGTTTAGGTCATGTGACCCTTAGAGCCAGCACCAGTAGTAACATTCGCTCTGAAGTTTTAATGGAAGGTGAGTATGGGTTTATCGGGAAATCTGTACCGACTAATAACCCAGCAGGGCAGCGCATCATATTTTGCGGGGGAGACGGAACCAGTTCTTCTACTGGTGCACAGATTACGCTTTACGGTGCGAGCAACACAGCTTCTCGCAGGATAGTTTACAACGGAAATGAACATCTGTTTCAGGGTGCTGATGTTAAGCCTTATAACGATAACGTCATTGCGCTTGGTGGACCAAGAAACCGTTTCACCACTGCATACCTCGGAAGTAACCCTATTGTTACTTCTAACGGGGAGAAGAAAACAGAGCCGGTAGTTTTTGATGATGCTTTCCTGGATGCCTGGGGTGACGTTCACTACATCATGTACCAGTGGTTAGATGCTGTTCAACTGAAAGGTAATGATGCTCGTATTCACTTCGGGGTTATTGCTCAACAAATTCGTGATGTATTCATTGCACATGGTCTGATGGATGAAAACAGTACGAATTGTCGTTATGCTGTTCTGTGCTATGACAAGTATCCACGGATGACCGATACGGTATTTTCACACAATGAAATCGTTGAACATACTGACGAGGAGGGTAATGTCACTACTACGGAAGAACCTGTATACACCGAGGTGGTTATTCATGAAGAGGGTGAGGAGTGGGGTGTTCGGCCTGACGGAATTTTCTTTGCTGAAGCCGCTTATCAGAGAAGAAAACTGGAAAGAATCGAAGCCAGACTTTCTGCTCTTGAACAGAAGTAA

Protein

Domains

Tail Spike Domain Segmentation

Taxonomy

Coding sequence (CDS)

Genome Context

Tertiary structure

Predicted Aligned Error (PAE)