Protein

Validated by sequence identity RBP function shown
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Genbank accession
QPI17475.1 [GenBank]
Protein name
hinge connector of long tail fiber, distal connector
RBP type
TSP
Evidence DepoScope
Probability 1,00
TF
Evidence GenBank
Probability 1,00
TSP
Evidence RBPdetect
Probability 0,85
TF
Evidence RBPdetect2
Probability 0,52
TF
Evidence UniProt/Swiss
Probability 1,00
TF
Evidence UniProt/TrEMBL
Probability 1,00
Seq2Symm
C3 confidence 0,978
C3 0,978
C1 0,315
D3 0,001
Predicted homo-oligomer symmetry (Seq2Symm, per-class probabilities; C1 = monomer, C2 = dimer, C3 = trimer).
Protein sequence
MADLKVGSTTGGSVIWHQGNFPLNPAGDDVLYKSFKIYSEYNKPQAADNDFVSKANGGTYASKVTFNAGIQVPYAPNIMSPCGIYGGNGDGATFDKANIDIVSWYGVGFKSSFGSTGRTVVINTRNGDINTKGVVSAAGQVRSGAAAPIAANDLTRKDYVDGAINTVTANANSRVLRSGDTMTGNLTAPNFFSQNPASQPSHVPRFDQIVIKDSVQDFGYY
Physico‐chemical
properties
protein length:221 AA
molecular weight: 23341,55310 Da
isoelectric point:7,77224
aromaticity:0,10407
hydropathy:-0,28597

Domains

View on InterPro
Domain architecture
QPI17475.1
1 221 aa
STR 56–195 ·
ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped
Proteins with similar domain architecture

Tail Spike Domain Segmentation

Segmented into three structural domains: N-terminal, central, and C-terminal.

Domain layout
QPI17475.1
1 221 aa
Domain Start End Length (AA) Confidence
N-terminal 1 77 77 0,6703
Central domain 78 210 134 0,1309
C-terminal 211 221 10 0,9522
N-terminal Central domain C-terminal

View these domains on the 3D structure via the Color by → Tail spike option in the Tertiary structure section below.

Taxonomy

Phage
Escherichia phage T4 [NCBI] · taxon 2681598
Uroviricota Caudoviricetes Pantevenvirales Tevenvirinae Tequatrovirus
Host
Escherichia coli B [NCBI] · taxon 37762
Bacteria Proteobacteria Gammaproteobacteria Enterobacteriales Enterobacteriaceae Escherichia

Coding sequence (CDS)

No CDS data available.

Genome Context

Tertiary structure

QPI17475.1
ESMFold structure
Source ESMFold
pLDDT 70.4
Oligomeric state monomer
Download structure

Experimental validation

Validated by sequence identity

The evidence was produced on a different entry with an identical sequence. Strong, but the experiment was not done on this protein.

Tier Source Assay Claim Reference
Validated by sequence identity UniProt
P03743
 ECO:0000269:FUNCTION:8709154 RBP Structural component of the distal-half of the long-tail fiber. The long-tail fiber of T4 is about 1600 Angstroms long with a kink in the middle that divides the fiber into proximal and distal halves. The thin tip of the distal half-fiber interacts with the bacterial lipopolysaccharide receptor and specifies the host range of the phage PMID 8709154
Validated by sequence identity UniProt
P03743
 ECO:0000269:SUBUNIT:8709154 RBP The long-tail fibers are trimeric, with a stoichiometry of gp34/gp37/gp36/gp35 of 3:3:3:1 PMID 8709154
Validated by sequence identity UniProt
P03743
 protein_existence:evidence_at_protein_level 1: Evidence at protein level —

Rows marked “Validated by sequence identity” come from a different entry carrying the same sequence — the experiment was not performed on this protein.