Phage RBP Database

UniProt accession

E7DYX2 [UniProt]

Protein name

Putative tail fiber protein

RBP type

TF

Evidence UniProt/TrEMBL

Probability 1,00

TF

Evidence GenBank

Probability 1,00

TF

Evidence Phold

Probability 1,00

TF

Evidence RBPdetect

Probability 0,89

TF

Evidence RBPdetect2

Probability 1,00

Protein sequence

MSVVVSGTLKSPDGEAISGANITLTALTVSPDALSGTSASAVTREGGYYGMTMDPGEYAVSVTVKGKTAVYGRVRIEGTESTVTLNMLLRRSLVEVSIPGELLTDFRQIQNNVADDLATIRRLNEDTATKNTQATQSKESAAASAKSASDSAKTATSRAAEAGQKATDATEAATRAVTAAGNAEESSTRAGESEKAAGADAEKARQHAEKARLAQESAGEILKRAEAATVSAEEARRMAENARGPRGPQGETGPKGDVGPKGETGPVGPQGPAGPKGERGDVGAQGAVGPAGPRGEKGEQGERGPQGIPGLKGDTGERGPKGDQGDMGPKGEKGDPGGPAGPQGPKGERGEAGPQGPMGARGERGETGPRGEPGPAGPRGERGETGPQGPRGEPGPAGSAANVADATTAQKGIVQLSSATDSDDETKAATPKAVKAAMDVANEAKTKAEEAAAGGGVPGPKGDKGDTGPAGPAGPKGDKGERGDTGPVGATGERGPAGDAGPAGPQGPKGDRGERGETGLTGNAGPQGPKGDTGAAGPAGPQGPKGETGAAGPVGATGPQGPKGDPGETQIRFRLGPGNIIETNSHGWFPDTDGALITGLTFLDPKDATRVQGFFQHLQVRFGDGPWQDVKGLDEVGSDTGRTGE

Physico‐chemical properties

protein length:	645 AA
molecular weight:	63954,92270 Da
isoelectric point:	5,16089
aromaticity:	0,02016
hydropathy:	-0,79690

Domain architecture

E7DYX2

1 645 aa

ATT 5–93 · STR 244–302 · STR 340–396 · STR 407–448 · STR 456–514 · RBD 571–634 ·

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

InterPro domains

IPR008969
ATT

IPR008969 Coil IPR008160 IPR008160 IPR005068 IPR008160 IPR009640

PF13620
ENZ

PF13620 IPR050149 IPR009640

G3DSA:2.60.40.1120
STR

G3DSA:2.60.40.1120

E7DYX2

1645 aa

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

Novel HMM domains (de novo, PhaRBP-HMM)

Experimental de novo families on regions without InterPro annotation. Separate from the InterPro architecture above.

DC_1608
STR

DC_1608

DC_1453
STR

DC_1453

E7DYX2

1645 aa

InterPro domain annotations

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
IPR008969	ATT	IPR008969	5	93	Merged direct domain	Carboxypeptidase-like, regulatory domain superfamily	N-terminal	Low	Positional only	16 proteins / 16 hits
PF13620	ENZ	DC_0734	5	86	InterPro cluster	Carboxypeptidase regulatory-like domain	C-terminal	High	Text match	4 proteins / 4 hits
G3DSA:2.60.40.1120	STR	G3DSA:2.60.40.1120	5	98	Merged direct domain	G3DSA:2.60.40.1120	Central	Low	Positional only	6 proteins / 6 hits
Coil	Unmapped	-	222	242	Coils	Coil	-	-	-	-
IPR008160	STR	DC_0536	244	302	InterPro cluster	Collagen triple helix repeat	C-terminal	High	Text match	355 proteins / 386 hits
IPR050149	Unmapped	-	244	568	InterPro	Collagen superfamily	-	-	-	-
IPR008160	STR	DC_0536	340	396	InterPro cluster	Collagen triple helix repeat	C-terminal	High	Text match	355 proteins / 386 hits
IPR005068	STR	DC_0738	407	448	InterPro cluster	Bacteriophage lambda, Tail fiber protein, repeat-2	Central	High	Text match	217 proteins / 347 hits
IPR008160	STR	DC_0536	456	514	InterPro cluster	Collagen triple helix repeat	C-terminal	High	Text match	355 proteins / 386 hits
IPR009640	RBD	DC_0593	571	634	InterPro cluster	Bacteriophage 933W, L0121, tail fibre, C-terminal	C-terminal	Low	Positional only	120 proteins / 125 hits
IPR009640	RBD	DC_0593	575	634	InterPro cluster	Bacteriophage 933W, L0121, tail fibre, C-terminal	C-terminal	Low	Positional only	120 proteins / 125 hits

Proteins with similar domain architecture

Phage

Enterobacteria phage VT2phi_272 [NCBI] · taxon 936054

Uroviricota Caudoviricetes Sepvirinae Oslovirus PA2

Host

Escherichia coli O157:H7 [NCBI] · taxon 83334

Bacteria Proteobacteria Gammaproteobacteria Enterobacteriales Enterobacteriaceae Escherichia

Genbank protein accession

ADU03741.1 [NCBI]

Genbank nucleotide accession

HQ424691 [NCBI]

CDS location

range 45321 -> 47258
strand +

CDS

GTGAGTGTTGTTGTTTCGGGGACGCTGAAATCTCCTGATGGTGAGGCGATATCAGGAGCAAATATTACCCTGACGGCGCTGACAGTTTCACCGGATGCGCTCAGCGGCACCAGTGCGTCGGCAGTGACCCGTGAAGGTGGATATTACGGAATGACGATGGATCCGGGGGAGTATGCGGTTTCGGTGACGGTGAAAGGGAAGACTGCTGTCTACGGACGTGTGCGTATTGAGGGGACCGAAAGTACGGTGACGCTCAATATGCTGTTACGCCGCAGTCTTGTTGAGGTTAGCATACCCGGAGAACTGCTGACAGATTTCCGGCAGATACAGAATAATGTGGCTGATGACCTTGCCACTATTCGTCGCCTGAATGAAGACACGGCGACAAAAAACACTCAGGCCACACAGTCAAAAGAAAGTGCAGCAGCCAGTGCGAAGAGTGCATCTGACAGTGCAAAGACGGCAACCAGCAGGGCGGCTGAAGCCGGACAAAAAGCGACTGATGCCACTGAGGCTGCGACCCGTGCAGTCACAGCAGCGGGGAATGCAGAGGAAAGCTCGACCCGTGCCGGAGAGTCTGAAAAAGCCGCCGGAGCTGATGCAGAAAAAGCCAGACAGCATGCTGAAAAGGCCAGGCTGGCGCAGGAGAGCGCCGGAGAGATCCTTAAGCGGGCAGAGGCTGCCACTGTCAGTGCTGAAGAGGCCAGACGTATGGCTGAGAATGCACGGGGGCCCCGGGGGCCTCAGGGAGAAACTGGTCCGAAGGGGGATGTCGGTCCTAAAGGCGAAACAGGTCCAGTGGGCCCTCAAGGGCCCGCAGGGCCGAAAGGTGAGCGTGGTGACGTTGGTGCTCAGGGGGCTGTAGGGCCTGCTGGTCCGCGTGGTGAGAAGGGCGAACAGGGGGAGCGAGGACCGCAGGGAATACCAGGCCTGAAGGGGGATACCGGAGAGCGGGGGCCTAAAGGGGACCAGGGGGATATGGGGCCAAAAGGCGAGAAAGGTGATCCGGGAGGTCCTGCAGGCCCGCAAGGTCCTAAAGGCGAACGAGGAGAAGCCGGACCACAGGGACCGATGGGAGCACGAGGTGAGCGTGGGGAGACTGGCCCCCGAGGTGAACCTGGTCCTGCAGGTCCGAGAGGCGAACGAGGAGAGACCGGACCTCAGGGACCTCGTGGAGAGCCAGGTCCGGCAGGCAGCGCTGCAAATGTGGCTGATGCAACGACGGCACAGAAGGGAATTGTGCAGTTAAGCAGCGCAACGGACAGTGATGATGAAACGAAGGCTGCCACCCCGAAAGCGGTGAAAGCGGCAATGGATGTGGCAAATGAAGCGAAAACAAAGGCAGAAGAGGCTGCAGCAGGAGGTGGTGTTCCCGGTCCGAAAGGAGATAAAGGGGACACGGGGCCAGCAGGTCCGGCTGGGCCGAAGGGTGATAAGGGAGAGCGCGGTGACACCGGCCCTGTCGGGGCAACCGGCGAACGGGGACCGGCAGGTGATGCTGGTCCGGCAGGCCCGCAGGGGCCGAAAGGTGACAGGGGAGAGCGGGGAGAGACCGGTCTGACGGGAAATGCAGGTCCACAGGGTCCAAAGGGAGATACCGGTGCGGCAGGCCCGGCAGGCCCACAGGGACCGAAAGGAGAAACAGGTGCGGCAGGCCCGGTGGGGGCGACCGGACCTCAGGGGCCGAAGGGCGACCCGGGGGAGACGCAAATACGGTTCCGTCTGGGGCCGGGAAACATTATTGAGACAAACAGCCATGGCTGGTTCCCGGATACAGATGGCGCACTCATCACCGGACTGACCTTTCTTGACCCCAAAGATGCCACACGGGTTCAGGGTTTTTTTCAGCATTTGCAGGTCAGGTTTGGTGACGGGCCGTGGCAGGATGTCAAGGGGCTGGATGAAGTGGGCAGTGATACAGGCAGAACAGGAGAATGA

	Description	Category	Evidence (source)
GO:0031012	extracellular matrix	Cellular Component	IEA:TreeGrafter (UniProt)
GO:0005615	extracellular space	Cellular Component	IEA:TreeGrafter (UniProt)
GO:0046718	symbiont entry into host cell	Biological Process	IEA:InterPro (UniProt)
GO:0019062	virion attachment to host cell	Biological Process	IEA:InterPro (UniProt)

Protein

Domains

Taxonomy

Coding sequence (CDS)

Genome Context

Gene Ontology

Tertiary structure

Predicted Aligned Error (PAE)