Phage RBP Database

Genbank accession

URY10781.1 [GenBank]

Protein name

central tail fiber J

RBP type

TF

Evidence Phold

Probability 1,00

TSP

Evidence RBPdetect

Probability 0,86

TF

Evidence RBPdetect2

Probability 0,97

Protein sequence

MAENMITGSKGGSSKPYVPKEMEDNLISINKIKILLAVSDGECDPDFTLRDLYLDDVPVIADDGTVNYQGVSAEFRPGTQTQDYIQGFTDTSSEVTLARDITTSNPYVISVTNKTLSAIRIKMLMPTGIKQEDNGDLVGVKVTYAVDMAVDGDSYKEVLRDTIEGKTRSGYDRSRRIDLPAFNDRVLLRVRRVTADSASSRVTDLIKLQSYAEVIDAKFRYPLTGLVYVEFDSELFPNQIPNISIKKKWKLINVPSNYDPVMREYHGSWNGTFKKAWSNNPAWVLYDIITNQRYGLDQRELGVQVDKWSLYEAAQYCDQKVPDGKGGTEPRYLCDVVIQSQIEAYQLIRDICSIFRGMSFWNGESLSIVIDKPRDPSYIFTNDNVVDGDFQYTTASEKSMYTQCNVTFDDEQNMYQQDVEGVFDTEAALRFGYNPTSITAIGCTRRSEANRRGRWILKTNLRSTTVNFATGLEGMIPSIGDVIAIADNFHSSNLKLNLSGRVMEVSGLQVFVPFKIDARPGDFIIINKPDGKPVKRTISKVSGDGKTIELNIGFGFEVKPDTVFAIDRTDIALQQYVVTSIGKGDGDDEFTYSITAVEYDPNKYDEIDYGVNIDDRPTSIVQPDKMAAPENVQISSYSRIVQGASVETMVVSWDKVPYASLYEMQWRKGDGNWLNTPQTANKEIEVEGIYSGNYQVRVRSVSASGSTSPWSRIVTASLTGKVGEPGAPVNLTASDNEVFGIRVKWGMPEGSGDTAYIELHQSPDGTAENSSLLTLIPYPQYEYWHGTLPAGHVVWYRIRSVDRIGNVSGWTNFVRGMASDDVEAVLGDILDKIFDTEAGKDLKENAIDSANKIKDQAQSIIQNALANDADVRIMMKENGKRKAEFRQSIQLIADETEARVTAMTQLKAEFDEEITSEVTRLDQAIATESETRATAIEELKSQIDDDIQGQLTRVEEAIASETEARVSADTALTAKFGDVESALTEKLDSWAGVNGVGAQYAMKLGLTYNGQKYSAGMVMQLSQGSSGLISQILFDANRFAIMTSSTGGSYTLPFVVENNQVFINSLLVKDGSITNAKIGNVIQSNNFVSGVQGWMINKSGAAELNNVTVRGSLYASNGSFAFNGTNNTVVINNNGITVNLPNGGRVVVGVW

Physico‐chemical properties

protein length:	1151 AA
molecular weight:	127058,90520 Da
isoelectric point:	4,78206
aromaticity:	0,08601
hydropathy:	-0,32268

Domain architecture

URY10781.1

1 1151 aa

ATT 92–217 · ATT 341–488 · STR 625–722 · STR 724–815 · RBD 983–1119 ·

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

InterPro domains

IPR053171
Unmapped

IPR053171 IPR015406

IPR055385
ATT

IPR055385 IPR032876 IPR036116 IPR013783

IPR013783
STR

IPR013783

IPR003961
STR

IPR003961

IPR003961
STR

IPR003961

URY10781.1

11151 aa

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

Novel HMM domains (de novo, PhaRBP-HMM)

Experimental de novo families on regions without InterPro annotation. Separate from the InterPro architecture above.

DC_0014
STR

DC_0014

URY10781.1

11151 aa

InterPro domain annotations

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
IPR053171	Unmapped	-	3	874	InterPro	Viral Tip Attachment Protein	-	-	-	-
IPR055385	ATT	DC_0360	92	217	InterPro cluster	Tip attachment protein J, HDII-ins2 domain	N-terminal	High	Text match	1136 proteins / 1139 hits
IPR032876	ATT	DC_0307	341	488	InterPro cluster	Tip attachment protein J	Central	Medium	Text match	1111 proteins / 1112 hits
IPR036116	STR	IPR036116	625	716	Merged direct domain	Fibronectin type III superfamily	Central	Low	Positional only	52 proteins / 52 hits
IPR013783	STR	IPR013783	627	719	Merged direct domain	Immunoglobulin-like fold	Central	Low	Positional only	144 proteins / 144 hits
IPR003961	STR	DC_0003	628	722	InterPro cluster	Fibronectin type III	Central	High	Text match	998 proteins / 1603 hits
IPR003961	STR	DC_0003	628	716	InterPro cluster	Fibronectin type III	Central	High	Text match	998 proteins / 1603 hits
IPR013783	STR	IPR013783	724	815	Merged direct domain	Immunoglobulin-like fold	Central	Low	Positional only	144 proteins / 144 hits
IPR015406	RBD	DC_0135	983	1119	InterPro cluster	Tip attachment protein J, central straight fiber domain	C-terminal	High	Text match	1265 proteins / 1266 hits

Proteins with similar domain architecture

Segmented into three structural domains: N-terminal, central, and C-terminal.

Domain layout

URY10781.1

1 1151 aa

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	509	509	0,9097
Central domain	510	1083	575	0,0501
C-terminal	1084	1151	67	0,7449

Note: Constraints were applied during segmentation.
Fixed 29 C-terminal predictions appearing before Central domain

N-terminal Central domain C-terminal

View these domains on the 3D structure via the Color by → Tail spike option in the Tertiary structure section below.

Phage

Shigella phage ESh4 [NCBI] · taxon 2950783

Viruses Duplodnaviria Heunggongvirae Uroviricota Caudoviricetes

Host

Shigella sp. [NCBI] · taxon 625

cellular organisms Bacteria Pseudomonadati Pseudomonadota Gammaproteobacteria Enterobacterales

Genbank protein accession

URY10781.1 [NCBI]

Genbank nucleotide accession

ON528718.1 [NCBI]

CDS location

range 16982 -> 20437
strand -

CDS

ATGGCTGAAAATATGATAACGGGAAGTAAGGGAGGATCATCAAAACCTTATGTTCCGAAAGAGATGGAAGATAACCTGATCTCAATCAACAAAATCAAAATCCTTCTTGCCGTTTCCGATGGCGAGTGCGATCCAGATTTTACACTTCGCGATCTGTATCTTGATGATGTTCCGGTAATTGCAGACGACGGAACTGTTAACTACCAAGGTGTGAGCGCAGAGTTTCGCCCAGGTACACAGACTCAAGATTACATCCAGGGATTTACTGACACATCAAGCGAAGTGACGCTGGCGCGTGATATTACCACGTCAAATCCTTATGTGATTTCCGTAACCAACAAAACATTATCTGCTATCAGAATCAAAATGCTAATGCCAACAGGCATTAAGCAAGAGGATAACGGCGATCTTGTCGGCGTTAAGGTTACTTATGCTGTTGATATGGCTGTTGACGGAGACTCTTACAAAGAAGTATTGCGAGACACTATCGAAGGTAAAACGCGTTCCGGTTACGACAGAAGCCGAAGGATTGACCTTCCGGCATTTAATGATCGCGTATTGCTTAGGGTTAGAAGGGTAACGGCAGACAGCGCATCTTCTCGCGTTACTGATCTGATTAAGCTACAAAGTTACGCTGAGGTTATTGATGCAAAATTCCGTTACCCTCTGACTGGCCTTGTATACGTTGAATTTGACAGCGAGTTGTTCCCTAACCAGATCCCTAACATTTCAATCAAGAAGAAATGGAAGTTGATTAATGTTCCGAGCAATTACGATCCGGTAATGCGAGAGTATCACGGCTCATGGAATGGTACGTTCAAGAAAGCGTGGTCTAACAATCCGGCGTGGGTACTTTATGACATTATCACAAACCAGCGATACGGATTAGATCAGCGAGAGCTTGGTGTACAGGTTGATAAGTGGAGTCTTTACGAAGCTGCGCAATACTGCGATCAGAAAGTTCCAGACGGAAAAGGAGGCACAGAGCCACGCTATCTATGTGATGTTGTTATCCAGAGTCAGATTGAGGCTTATCAGCTTATTCGTGATATTTGCTCAATATTCAGAGGCATGAGCTTTTGGAATGGGGAGAGCTTGTCAATCGTCATTGATAAGCCGCGCGATCCGTCGTACATCTTCACAAATGACAATGTTGTTGATGGTGATTTCCAGTACACAACAGCAAGTGAAAAGAGCATGTACACGCAGTGCAATGTGACGTTCGACGACGAACAAAACATGTATCAGCAGGACGTAGAAGGCGTGTTTGATACTGAGGCGGCACTACGCTTTGGATACAATCCGACAAGCATAACAGCGATCGGATGTACACGCAGGAGTGAGGCTAATCGGCGAGGTCGATGGATACTAAAAACCAACTTGCGCAGCACTACGGTAAACTTTGCTACTGGACTGGAAGGCATGATCCCATCAATAGGTGATGTGATTGCTATTGCTGACAACTTTCACAGCAGCAACCTGAAGTTAAACCTATCAGGGCGCGTGATGGAAGTTTCCGGCTTGCAGGTGTTCGTTCCGTTTAAGATTGATGCTAGACCAGGTGATTTCATTATCATCAACAAGCCGGACGGAAAGCCAGTTAAGCGCACAATCTCAAAAGTAAGCGGTGACGGAAAAACCATTGAGCTAAATATTGGGTTTGGATTTGAAGTTAAACCTGACACGGTTTTTGCAATCGACCGCACTGATATTGCATTGCAGCAATACGTTGTAACGAGTATCGGCAAAGGTGATGGTGATGATGAATTTACATACTCCATCACGGCTGTTGAATATGACCCTAACAAATACGACGAGATTGATTACGGAGTAAACATTGACGACAGGCCAACGTCAATTGTCCAGCCTGACAAAATGGCAGCACCGGAAAACGTGCAAATATCCTCATACTCGCGAATTGTCCAGGGTGCAAGCGTTGAAACAATGGTTGTGTCGTGGGATAAAGTACCTTACGCATCGCTGTATGAAATGCAGTGGCGAAAAGGTGATGGCAACTGGCTGAATACACCACAGACTGCAAACAAAGAAATTGAGGTTGAAGGTATTTATTCAGGAAACTACCAAGTAAGGGTCAGATCTGTTTCCGCTTCAGGTTCTACTTCTCCGTGGTCCAGAATTGTGACAGCTTCACTGACTGGTAAGGTGGGAGAGCCAGGCGCGCCAGTTAACTTAACAGCATCCGACAATGAGGTGTTTGGCATTCGTGTTAAGTGGGGTATGCCAGAAGGGAGCGGAGACACGGCATACATTGAGCTTCACCAGTCGCCGGATGGAACGGCTGAAAACTCAAGCCTGCTAACGCTGATCCCGTATCCACAATATGAATACTGGCACGGTACGCTTCCGGCTGGTCATGTTGTCTGGTATAGGATCCGCAGCGTTGACAGAATCGGCAACGTCTCCGGCTGGACTAATTTTGTTAGAGGTATGGCTTCAGATGATGTGGAGGCTGTTTTAGGAGATATTCTTGATAAGATTTTTGACACTGAAGCAGGAAAGGATCTGAAAGAGAATGCCATTGATAGCGCAAACAAAATCAAGGATCAGGCACAAAGCATCATTCAAAACGCATTGGCGAATGATGCAGACGTTAGGATTATGATGAAGGAAAACGGAAAACGCAAAGCCGAATTCAGGCAATCAATACAGTTGATCGCAGATGAAACTGAGGCGCGCGTTACCGCAATGACGCAACTCAAGGCTGAATTTGACGAGGAAATAACTAGCGAAGTAACAAGGCTTGATCAGGCAATTGCAACAGAATCGGAAACGCGAGCAACAGCCATTGAGGAATTGAAATCACAGATTGATGATGATATTCAGGGGCAATTAACGCGGGTTGAGGAGGCGATTGCAAGCGAAACAGAGGCGCGCGTTTCGGCTGATACAGCATTAACAGCGAAGTTTGGAGATGTTGAATCGGCACTTACTGAAAAACTTGATTCATGGGCTGGCGTTAATGGAGTTGGCGCACAGTACGCAATGAAATTGGGATTGACATATAACGGTCAGAAGTACAGCGCTGGTATGGTGATGCAGCTTTCACAGGGTTCATCCGGCCTTATTTCGCAGATTTTGTTTGATGCGAACAGGTTCGCTATCATGACAAGTTCTACTGGAGGATCGTATACGTTGCCTTTTGTGGTGGAAAATAACCAGGTATTCATTAACAGCCTGTTGGTGAAAGACGGTTCAATCACAAATGCTAAGATCGGTAACGTTATTCAATCAAACAACTTCGTATCTGGAGTGCAGGGGTGGATGATTAACAAATCAGGAGCAGCCGAGTTGAACAATGTTACTGTTAGAGGATCGCTTTATGCTTCAAACGGTAGTTTTGCTTTTAATGGAACAAATAACACCGTTGTTATAAATAACAATGGCATCACTGTAAACCTTCCCAATGGTGGACGAGTTGTTGTTGGTGTGTGGTAA

Title	Authors	Date	PMID	Source
Design of a bacteriophage cocktail active against Shigella species and testing of its therapeutic potential in Galleria mellonella	Filippov,A.A., Su,W., Kevorkian,R.T., Sergueev,K.V., Srijan,A., He,Y., Lurchachaiwong,W., McGann,P.T., Ellison,D.W., Swierczewski,B.E. and Nikolich,M.P.	—	—	GenBank

Protein

Domains

Tail Spike Domain Segmentation

Taxonomy

Coding sequence (CDS)

Genome Context

Tertiary structure

Predicted Aligned Error (PAE)

Literature