Phage RBP Database

Genbank accession

AZF90573.1 [GenBank]

Protein name

tail fiber protein and host specificity

RBP type

TF

Evidence Phold

Probability 1,00

TF

Evidence RBPdetect2

Probability 0,98

Seq2Symm

C3 confidence 0,586 truncated

C3	0,586
C1	0,072
C2	0,002

Predicted homo-oligomer symmetry (Seq2Symm, per-class probabilities; C1 = monomer, C2 = dimer, C3 = trimer).

Protein sequence

MLLTIHDANLQKIGFIDNEKQETLNFYNDTWTRNLGTASSTFEFTVSKKQLLSDTANKPLYNQLNERSFVSFKHKGQTYLFNIMKVEENERWIRCYCENLNLELINEYTNPYKADRPLSFAEYLDVFEIPQFAMVKIGVNEISDQKRTLEWEGQDTKLARLLSLANKFDAEVEFVTQLNDDSSIKQLVLNVYHKADDSHTGVGRIRGDIRLTFEKNIKSMTRKIDKTEVYTLVVPYGKSKESHEGEQEVRVYIDNLPPWEEKDDNGIVIFKQEGVNLYAPHAADLYPSTFGVSTQSNKWIRKDLEVDSDNPNVIRAAGIANLRKHAYPAITYEVDGFIDVEIGDTITIHDKGFTPALDVRARAVEQKISFSNPTNNKTTFGNFKELENRTSGDLRSVFEQMVENIRPYNILVSTDNGVLFKNNTGQSTLRPTLKRGNQVINATYRFVIDGSIVSSGLTYTVKASDITKPTVITISAWVGNKEVASEEVTFLNVSDGKQGPQGPQGPKGADGRTPYIHTAWAYSADGTDRFTTVYPNLNLIDGTRDFSGNWNRAWAWQTDGTYKGLIVKKRTDLWKGIDKTFTAPKNGTYTFSAYIKCSGNTANPARHINLNGFWDRNTYKTYGNNFDWLRDSFSVKLKTGDTIAARYEISGKGTLWTAGHKWEEGSTATPWMPSASEVTTDDYPKYIGQYTNYNQVDSPNPQDYTWSLIRGNDGADGKTPYVHFAYADSADGRTGFSLTQTGSKRYLGVYTDFNQADSTNPSDYTWNDTAGSISVGGRNLLNGSKGPFKPDRKPTTNFDNIGLYQNETSVYLEENKNYIVSAKTDGIFTSTHNPSVDSDNVVLWLYRPWDVWKLISDSKTGTTGTQFIWDHPTGTYHLRVNTYHKEAIKSVWEVKIEEGTVKTDWTPSVDDVQKDIDSKADDALTQAQLNRLSEINSVMKAELEAKASLATVNQWIKAYQDFVNANSADRAQAQKALADASARVVKLENNLNDMSERWNFIDNYMAASNDGLVIGKKDNSSSIMFNPNGRISMFSAGNEVMYISQGVIHIENGIFSKTIQIGRFREEQDFINPDRNVIRYAGGI

Physico‐chemical properties

protein length:	1084 AA
molecular weight:	122262,47300 Da
isoelectric point:	5,69421
aromaticity:	0,10886
hydropathy:	-0,60249

Domain architecture

AZF90573.1

1 1084 aa

ENZ 144–385 · RBD 568–663 ·

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

InterPro domains

IPR007119
Unmapped

IPR007119 IPR008983 Coil

IPR010572
ENZ

IPR010572 IPR008983

AZF90573.1

11084 aa

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

Novel HMM domains (de novo, PhaRBP-HMM)

Experimental de novo families on regions without InterPro annotation. Separate from the InterPro architecture above.

DC_0255
STR

DC_0255

AZF90573.1

11084 aa

InterPro domain annotations

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
IPR007119	Unmapped	-	57	381	InterPro	Phage tail spike protein, N-terminal domain	-	-	-	-
IPR010572	ENZ	DC_0675	144	385	InterPro cluster	Tail spike domain	Central	High	Text match	419 proteins / 419 hits
IPR008983	RBD	IPR008983	568	663	Merged direct domain	Tumour necrosis factor-like domain superfamily	C-terminal	Low	Positional only	19 proteins / 19 hits
IPR008983	RBD	IPR008983	578	647	Merged direct domain	Tumour necrosis factor-like domain superfamily	C-terminal	Low	Positional only	19 proteins / 19 hits
Coil	Unmapped	-	970	997	Coils	Coil	-	-	-	-

Proteins with similar domain architecture

Phage

Streptococcus phage CHPC869 [NCBI] · taxon 2365041

Uroviricota Caudoviricetes Aliceevansviridae Brussowvirus Brussowvirus CHPC869

Host

Streptococcus thermophilus [NCBI] · taxon 1308

Bacillota Bacilli Lactobacillales Streptococcaceae Streptococcus Streptococcus thermophilus

Genbank protein accession

AZF90573.1 [NCBI]

Genbank nucleotide accession

MH937464.1 [NCBI]

CDS location

range 16516 -> 19770
strand +

CDS

ATGTTGCTAACAATTCACGATGCTAATTTGCAGAAGATTGGCTTCATCGATAACGAGAAGCAAGAAACGTTAAATTTCTATAATGATACTTGGACCCGAAACCTTGGAACAGCATCAAGCACGTTCGAGTTTACTGTTTCTAAAAAACAGCTACTTAGCGATACAGCGAATAAGCCGCTTTACAACCAACTAAACGAGCGCTCTTTCGTTTCCTTTAAACACAAAGGTCAGACGTATCTTTTTAATATCATGAAAGTGGAAGAGAATGAGCGATGGATACGTTGCTATTGTGAGAACTTAAACCTTGAGCTGATAAACGAGTACACGAACCCTTACAAGGCTGATAGACCTTTGTCATTTGCGGAGTATCTTGATGTTTTTGAAATTCCTCAGTTTGCGATGGTTAAAATAGGTGTTAATGAGATCTCTGATCAGAAGAGAACGCTCGAGTGGGAAGGGCAGGACACAAAACTGGCAAGGCTCTTAAGCTTGGCCAATAAATTTGACGCTGAAGTTGAATTTGTGACTCAACTTAACGATGACAGTTCAATTAAGCAACTCGTTTTGAACGTTTACCATAAAGCGGACGACTCGCACACTGGTGTGGGTCGAATTCGCGGTGACATTCGTCTGACTTTTGAAAAGAATATCAAATCAATGACGAGAAAGATTGATAAGACTGAAGTTTATACGTTGGTAGTTCCTTATGGAAAATCAAAAGAGAGTCATGAAGGCGAGCAAGAAGTACGTGTATACATTGACAACCTCCCACCTTGGGAGGAAAAGGACGACAATGGTATCGTTATTTTCAAACAAGAGGGCGTAAACCTCTACGCACCTCATGCAGCGGACTTATACCCGTCTACTTTTGGCGTATCAACTCAATCTAATAAATGGATTCGAAAAGACTTAGAGGTTGATAGCGATAATCCAAATGTCATCCGTGCTGCAGGAATTGCAAATTTGCGTAAACACGCATATCCAGCTATCACTTACGAGGTTGACGGTTTTATTGATGTCGAAATTGGGGATACGATAACAATCCACGACAAAGGATTCACACCAGCGCTTGACGTGAGAGCGCGTGCCGTTGAGCAAAAAATTAGCTTCAGCAATCCAACCAACAATAAGACCACTTTCGGAAACTTCAAAGAGCTTGAAAATAGGACATCTGGAGACCTTAGGAGCGTTTTCGAGCAAATGGTTGAGAACATTCGACCATACAATATCCTAGTCTCAACTGATAACGGTGTTTTGTTTAAAAACAATACAGGGCAGTCAACACTACGCCCAACATTAAAACGAGGGAATCAGGTTATTAATGCAACCTATCGATTTGTGATCGATGGCTCTATTGTTAGCTCTGGTCTGACCTATACCGTCAAAGCAAGCGATATCACAAAACCAACTGTAATTACAATTTCAGCGTGGGTAGGTAATAAAGAAGTAGCTTCAGAGGAAGTTACTTTTTTAAATGTTTCAGATGGGAAACAAGGCCCACAAGGACCACAAGGACCTAAAGGAGCAGACGGACGAACACCTTATATCCATACGGCATGGGCTTACAGTGCAGATGGTACAGATAGATTCACAACGGTTTATCCGAACTTGAACTTGATTGATGGTACTAGAGATTTCAGTGGTAATTGGAATAGAGCGTGGGCATGGCAAACTGACGGGACATATAAAGGCTTAATAGTTAAGAAAAGAACAGATTTATGGAAGGGGATTGATAAAACGTTTACTGCACCAAAAAATGGTACTTATACTTTCTCGGCTTATATTAAATGTTCAGGAAACACTGCTAATCCAGCCAGACATATTAATTTAAATGGATTTTGGGATAGAAATACTTATAAGACTTATGGAAATAACTTTGATTGGTTAAGAGATAGCTTTTCTGTAAAACTAAAAACCGGAGATACTATTGCTGCAAGATACGAAATATCAGGAAAAGGCACCTTATGGACTGCTGGTCACAAGTGGGAAGAGGGTTCAACCGCCACTCCTTGGATGCCATCGGCTAGTGAAGTAACAACCGATGATTATCCAAAATATATTGGACAATACACAAACTATAATCAAGTTGATAGTCCCAACCCTCAAGACTATACATGGAGCTTAATTCGAGGTAATGATGGTGCTGATGGTAAAACACCTTATGTTCATTTCGCTTATGCTGATAGTGCAGATGGTAGAACTGGTTTCAGTTTGACACAGACTGGAAGTAAGCGCTATTTAGGTGTGTACACAGATTTCAATCAAGCGGACAGTACTAATCCTTCTGACTACACGTGGAACGATACTGCGGGTAGTATATCTGTTGGTGGCAGGAATCTCTTGAATGGCTCGAAAGGTCCTTTTAAACCTGATCGTAAACCGACAACTAATTTTGATAATATTGGTCTTTACCAAAATGAAACTTCAGTTTATTTAGAGGAAAACAAAAATTACATTGTTAGCGCAAAAACAGATGGCATTTTTACTTCAACCCACAATCCAAGTGTTGATAGTGACAATGTGGTGCTATGGCTATATCGTCCATGGGATGTGTGGAAACTTATATCCGATTCAAAAACAGGTACTACAGGAACGCAGTTTATTTGGGATCATCCGACAGGTACATATCATCTTCGTGTCAATACATATCATAAAGAAGCTATCAAATCTGTTTGGGAAGTGAAGATTGAAGAAGGAACAGTCAAAACAGATTGGACACCTTCTGTCGATGATGTACAAAAAGATATAGACAGTAAGGCTGATGATGCATTAACACAAGCCCAGTTGAATAGATTAAGTGAAATTAATTCGGTGATGAAAGCAGAGCTCGAAGCAAAAGCATCCCTTGCCACTGTTAATCAATGGATTAAGGCTTATCAAGATTTTGTTAACGCAAATAGCGCAGATCGCGCACAAGCTCAAAAGGCTTTGGCAGATGCCAGTGCACGAGTAGTGAAACTAGAAAATAACTTAAACGATATGTCAGAGCGTTGGAATTTTATCGATAACTACATGGCAGCATCAAATGATGGTTTGGTTATCGGGAAGAAAGATAACTCTAGCTCTATCATGTTCAACCCAAACGGTCGTATATCAATGTTTTCAGCTGGTAATGAGGTAATGTATATCTCTCAGGGTGTGATTCACATTGAAAACGGTATTTTTTCTAAGACTATTCAAATTGGACGATTCCGAGAAGAACAAGATTTTATTAATCCGGATCGCAACGTCATCCGCTATGCAGGAGGTATTTAA

Title	Authors	Date	PMID	Source
A comparative genomics approach for identifying host-range determinants of bacteriophages infecting Streptococcus thermophilus	Szymczak,P., Rau,M.H., Monteiro,J.M., de Pinho,M.G., Filipe,S.R., Vogensen,F.K., Zeidan,A. and Janzen,T.	2019-05-29	—	GenBank

Protein

Domains

Taxonomy

Coding sequence (CDS)

Genome Context

Tertiary structure

Predicted Aligned Error (PAE)

Literature