Phage RBP Database

Genbank accession

NP_536838.1 [GenBank]

Protein name

tail fiber protein

RBP type

TF

Evidence GenBank

Probability 1,00

TF

Evidence Phold

Probability 1,00

TSP

Evidence RBPdetect

Probability 0,84

TF

Evidence RBPdetect2

Probability 0,96

Protein sequence

MASLITPQFERYVAEQTIARGTVQFDEFIFANIPGLNENNLAQYLTMPTSAQIVHRQAVSQSGVINENAVVYSVTIGTEVGDFDFNFIGLINRSKNLLAVAVQTDTVKKIRNKNAVQGNSITRNMLLEFSGAKALTGINVNANTWQIDFTVRLHGLDEKIRLTNRDLYGRAVFFDDSFLVKRKTGNQFTIQPGTAYVEGVRMDLSALYNLTANNLPCSVYADLVHHCTVTGEYQTEIKYLTQSKADYVDTANRQHYVQILADIDSQGNVTDRRLLSPFLGMNPLTLDDTTENTQDKWGHTHKLPIASITKKGIVQLSSATNSNSETEAATSKAVKTAYDKAVEAKTTADGKVGLSGNEEIAGDKLFRSQTKFQNGVLISANKGHWDNGYKVYIGADSDNAHLVFGDDTLRLHGSNHRISYNNYHLFHEGYKPRFNEHIINKPNTLAGYGIGNFKVEQGQGDANGYKTDGNYYLASGQNLPENGAWHIEVVSGGATNAVRQIARKANDNKIKTRFFNGSNWSEWKETGGDGVPIGAVVSFPRAVTNPVGFLKADGTTFNQQTFPDLYRTLGDSNQLPDLTRSDTGMTAYFAVDNIPAGWIAFDSIRTTVTQQNYPELYRHLVGKYGSLSNVPLAEDRFIRNASNNLSVGETQSDEIKKHVHKVRTHWVNSSDSNIFYDKTKTVIDSRLRTATTTDDNLSDNGFMHPLLDSPMATGGNETRPKSLILKLCIKAINSLDDVQFWVKAFGVVENAGVLDAGTLAQNMQSVEQKIEENKQSTLREITNAKADINQQFLQAQKNLSQIGTLKKVWEGSVSTGSITISESCYGKTLIFYIQTADDQSNYGDSIEIVSFEAGAEDEGGGRLTSIREIVSKYNYRQVVPKEFTVYIAGDGKTITIGQLDARSIKRIYIR

Physico‐chemical properties

protein length:	910 AA
molecular weight:	100702,26840 Da
isoelectric point:	6,39975
aromaticity:	0,08901
hydropathy:	-0,42560

Domain architecture

NP_536838.1

1 910 aa

ATT 3–156 · STR 307–348 · STR 458–525 · ATT 529–581 · STR 583–731 ·

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

InterPro domains

IPR022225
ATT

IPR022225 IPR051934 cd19958 SSF88874 SSF88874 Coil

IPR005068
STR

IPR005068 cd19958 IPR037053

IPR011083
ATT

IPR011083

NP_536838.1

1910 aa

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

Novel HMM domains (de novo, PhaRBP-HMM)

Experimental de novo families on regions without InterPro annotation. Separate from the InterPro architecture above.

DC_2293
STR

DC_2293 DC_0818

NP_536838.1

1910 aa

InterPro domain annotations

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
IPR022225	ATT	DC_0271	3	156	InterPro cluster	Phage tail fibre protein, N-terminal domain	Central	Medium	Text match	271 proteins / 271 hits
IPR051934	Unmapped	-	297	346	InterPro	Bacteriophage Tail Fiber Structural Protein	-	-	-	-
IPR005068	STR	DC_0738	307	348	InterPro cluster	Bacteriophage lambda, Tail fiber protein, repeat-2	Central	High	Text match	217 proteins / 347 hits
cd19958	STR	DC_0464	458	525	InterPro cluster	cd19958	Central	Low	Positional only	1183 proteins / 1674 hits
cd19958	STR	DC_0464	460	525	InterPro cluster	cd19958	Central	Low	Positional only	1183 proteins / 1674 hits
SSF88874	STR	SSF88874	529	578	Merged direct domain	SSF88874	Central	Low	Positional only	109 proteins / 109 hits
IPR037053	ATT	IPR037053	530	581	Merged direct domain	Phage tail collar domain superfamily	N-terminal	Low	Positional only	37 proteins / 37 hits
IPR011083	ATT	DC_0235	534	578	InterPro cluster	Phage tail collar domain	C-terminal	Medium	Text match	1051 proteins / 1051 hits
SSF88874	STR	SSF88874	583	731	Merged direct domain	SSF88874	Central	Low	Positional only	109 proteins / 109 hits
Coil	Unmapped	-	767	798	Coils	Coil	-	-	-	-

Proteins with similar domain architecture

Segmented into three structural domains: N-terminal, central, and C-terminal.

Domain layout

NP_536838.1

1 910 aa

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	433	433	0,8101
Central domain	434	632	200	0,0929
C-terminal	633	910	277	0,6339

Note: Constraints were applied during segmentation.
Fixed 80 C-terminal predictions appearing before Central domain

N-terminal Central domain C-terminal

View these domains on the 3D structure via the Color by → Tail spike option in the Tertiary structure section below.

Phage

Haemophilus phage HP2 [NCBI] · taxon 2932882

Uroviricota Caudoviricetes Peduoviridae Hpunavirus HP2

Host

Haemophilus influenzae [NCBI] · taxon 727

cellular organisms Bacteria Pseudomonadati Pseudomonadota Gammaproteobacteria Pasteurellales

Genbank protein accession

NP_536838.1 [NCBI]

Genbank nucleotide accession

NC_003315.1 [NCBI]

CDS location

range 25007 -> 27739
strand +

CDS

ATGGCTAGTTTAATTACGCCACAATTTGAACGCTACGTTGCAGAACAAACTATTGCACGTGGCACAGTACAGTTTGATGAATTTATTTTTGCCAACATCCCAGGTTTAAATGAGAACAATCTTGCGCAATATCTCACTATGCCGACATCGGCACAAATTGTACATCGCCAAGCCGTATCGCAAAGTGGCGTGATTAATGAAAATGCCGTTGTGTATTCTGTGACGATTGGTACTGAAGTCGGCGATTTTGATTTCAATTTTATTGGTTTGATTAATCGTTCTAAAAATCTTTTAGCTGTTGCGGTGCAAACCGATACAGTGAAAAAAATCCGAAATAAAAATGCTGTGCAAGGCAACAGTATTACGCGCAATATGCTTTTAGAATTTAGTGGCGCAAAAGCTCTAACGGGCATTAATGTCAATGCGAACACTTGGCAAATTGATTTTACTGTGCGACTACATGGACTTGATGAAAAAATTCGTTTAACCAATCGTGATCTGTATGGCAGAGCAGTATTTTTCGATGATAGTTTTCTGGTTAAACGTAAAACAGGCAATCAATTTACGATTCAACCAGGCACGGCTTATGTTGAAGGCGTTCGTATGGATTTATCCGCACTTTATAACCTCACAGCAAACAATTTGCCATGTTCAGTTTATGCCGATCTAGTACATCATTGCACCGTAACGGGAGAATACCAAACCGAAATTAAGTATCTCACCCAATCAAAAGCAGATTATGTAGATACTGCAAACCGCCAACATTATGTACAAATTCTGGCGGATATTGATAGCCAAGGCAATGTGACAGATCGCCGCTTGCTTTCGCCGTTTTTAGGCATGAATCCGCTCACATTAGATGACACAACCGAAAACACCCAAGATAAATGGGGTCATACGCACAAGTTACCAATTGCCAGCATCACAAAAAAAGGCATTGTGCAACTAAGCTCAGCTACTAACAGCAACAGCGAAACCGAAGCTGCAACATCAAAAGCCGTGAAAACCGCCTATGACAAAGCAGTAGAAGCCAAAACTACGGCGGACGGTAAAGTGGGGTTAAGTGGCAATGAAGAAATAGCGGGGGATAAATTATTCCGTAGCCAGACTAAATTCCAAAATGGCGTGTTGATTTCTGCAAATAAAGGACACTGGGATAATGGGTATAAAGTCTATATTGGTGCAGATTCTGATAATGCACATCTGGTATTTGGCGATGATACATTGAGATTACACGGCTCAAATCATCGTATTTCGTATAATAATTATCATCTTTTCCATGAGGGCTACAAACCTCGTTTTAACGAACATATTATAAACAAACCTAATACACTTGCAGGCTATGGTATTGGGAATTTTAAAGTAGAACAAGGGCAGGGCGATGCCAATGGCTATAAAACCGATGGCAATTATTACTTAGCAAGCGGTCAAAATCTACCCGAAAATGGGGCATGGCATATTGAAGTAGTTAGCGGTGGGGCAACAAATGCGGTGCGTCAAATTGCACGTAAAGCAAATGATAACAAAATCAAAACACGCTTTTTTAATGGCTCAAATTGGTCAGAATGGAAAGAGACAGGCGGCGACGGCGTGCCTATTGGTGCGGTGGTGTCATTTCCTCGTGCGGTAACTAATCCCGTTGGTTTTTTAAAAGCCGATGGCACGACATTTAACCAACAAACCTTTCCCGATTTATACCGCACTTTGGGCGACAGCAACCAACTTCCTGATTTAACTCGTAGCGACACAGGCATGACGGCTTATTTTGCCGTGGATAACATTCCTGCAGGCTGGATTGCCTTTGATTCAATCAGAACAACCGTTACACAGCAAAATTACCCCGAGTTATATCGTCACTTAGTCGGTAAATATGGTTCTCTTTCAAATGTGCCATTAGCTGAAGACCGATTTATTAGAAATGCATCAAACAATTTATCGGTTGGTGAAACGCAAAGTGACGAGATTAAAAAGCACGTTCACAAAGTGAGAACACACTGGGTTAATTCAAGTGATAGTAATATTTTTTATGACAAAACGAAAACAGTTATAGATTCACGATTACGCACTGCAACTACAACTGATGATAATCTCAGTGATAATGGATTTATGCATCCGCTATTAGATAGCCCAATGGCAACAGGTGGAAATGAAACTCGCCCTAAATCATTAATCCTCAAATTATGCATCAAAGCCATTAACAGCCTTGATGACGTGCAATTCTGGGTGAAGGCTTTCGGTGTTGTTGAAAATGCAGGGGTGCTTGATGCGGGTACACTTGCGCAAAATATGCAAAGTGTTGAACAAAAAATAGAAGAGAATAAACAATCAACTTTGCGAGAAATCACCAATGCAAAAGCTGATATAAATCAGCAATTTTTGCAGGCACAAAAGAATTTATCTCAAATTGGCACATTAAAAAAAGTCTGGGAAGGTAGCGTGAGTACTGGGTCAATTACTATATCAGAGAGTTGCTATGGCAAAACGTTAATTTTTTATATTCAGACAGCAGATGATCAAAGTAATTACGGTGATTCCATTGAAATAGTCAGTTTTGAAGCGGGTGCAGAAGATGAAGGCGGAGGTCGTTTGACTAGTATTCGTGAAATAGTATCCAAATATAATTATCGCCAAGTAGTACCCAAAGAGTTCACTGTGTATATTGCTGGTGACGGTAAAACTATAACCATTGGCCAACTTGATGCACGTTCTATAAAACGTATTTATATTCGATAA

Title	Authors	Date	PMID	Source
Bacteriophage HP2 of Haemophilus influenzae	Williams,B.J., Golomb,M., Phillips,T., Brownlee,J., Olson,M.V. and Smith,A.L.	2002	12446640	GenBank

Protein

Domains

Tail Spike Domain Segmentation

Taxonomy

Coding sequence (CDS)

Genome Context

Tertiary structure

Predicted Aligned Error (PAE)

Literature