Phage RBP Database

Genbank accession

AKU42948.1 [GenBank]

Protein name

endopeptidase tail family protein

RBP type

TF

Evidence GenBank

Probability 1,00

TSP

Evidence RBPdetect

Probability 0,80

Protein sequence

MDYHDHLSVMDFNELICENLLDVDYGSFKEYYELNEARYITFTVYRTTHNSFVFDLLICENFIIYHGEKYTIKQTAPKVEGEKVFIEVTAYHIMYEFQNHSIESNKLDDDSSESSKTPEYTLEEYLRYGFANQKTSVKMTYKIIGDFKRKVPIDELGNKNGLEYCKEAVDLFGCIIYPNDTEIGFYSPETFYQRSEKVIRYQYNTDTVSATVSTLELRTAIKVFGKKYTAEEKKNYNPIRTTDIKYSNGFIKEGTYRTETIGSKATINFDCKYGNETVRFTIKKGSQGGIYKLILDGKQIKQISCFAKSVQSETIDLIKNIDKGKHVLEMIFLGEDPKNRIDISSNKKAKPCMYVGTEKSTVLNLIADNSGRNQYKAIVDYVADSAKQFGIRYANTQTNEDIETQDKLLEFAKKQINDTPKTELDVNYIGYEKIEPRDSVFFVHELMGYNTELKVVKLDRSHPFVNAIDEVSFSNEIKDMVQIQQALNRRVIAQDNRYNYQANRINHLYTSTLNSPFETMDIGSVLI

Physico‐chemical properties

protein length:	527 AA
molecular weight:	61003,13650 Da
isoelectric point:	5,66255
aromaticity:	0,11765
hydropathy:	-0,54554

Domain architecture

AKU42948.1

1 527 aa

ATT 4–90 · STR 91–192 · ENZ 193–486 ·

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

InterPro domains

G3DSA:6.20.110.10
ATT

G3DSA:6.20.110.10 G3DSA:3.55.50.40

IPR044051
ENZ

IPR044051 IPR010572

AKU42948.1

1527 aa

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

Novel HMM domains (de novo, PhaRBP-HMM)

Experimental de novo families on regions without InterPro annotation. Separate from the InterPro architecture above.

DC_1309
STR

DC_1309 DC_0297

AKU42948.1

1527 aa

InterPro domain annotations

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
G3DSA:6.20.110.10	ATT	G3DSA:6.20.110.10	4	90	Merged direct domain	G3DSA:6.20.110.10	N-terminal	Low	Positional only	47 proteins / 47 hits
IPR044051	ENZ	DC_0346	18	92	InterPro cluster	Prophage endopeptidase tail, N-terminal	N-terminal	High	Text match	59 proteins / 59 hits
G3DSA:3.55.50.40	STR	G3DSA:3.55.50.40	92	192	Merged direct domain	G3DSA:3.55.50.40	Central	Low	Positional only	63 proteins / 63 hits
IPR010572	ENZ	DC_0675	112	486	InterPro cluster	Tail spike domain	Central	High	Text match	419 proteins / 419 hits

Proteins with similar domain architecture

Segmented into three structural domains: N-terminal, central, and C-terminal.

Domain layout

AKU42948.1

1 527 aa

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	231	231	0,7872
Central domain	232	435	205	0,4969
C-terminal	436	527	91	0,0034

Note: Constraints were applied during segmentation.
Fixed 32 C-terminal predictions appearing before Central domain

N-terminal Central domain C-terminal

View these domains on the 3D structure via the Color by → Tail spike option in the Tertiary structure section below.

Phage

Staphylococcus phage vB_SauS_phi2 [NCBI] · taxon 1674930

Uroviricota Caudoviricetes Triavirus

Host

Staphylococcus aureus [NCBI] · taxon 1280

cellular organisms Bacteria Bacillati Bacillota Bacilli Bacillales

Genbank protein accession

AKU42948.1 [NCBI]

Genbank nucleotide accession

KT186243 [NCBI]

CDS location

range 15571 -> 17154
strand +

CDS

ATGGATTATCATGATCATTTATCAGTAATGGATTTTAATGAATTGATTTGTGAAAATTTACTAGATGTAGATTACGGTTCTTTTAAAGAATATTATGAACTGAATGAAGCTAGGTACATCACTTTTACAGTTTATAGAACTACTCATAATAGTTTTGTTTTCGATTTACTAATTTGTGAAAATTTCATTATTTATCATGGTGAAAAATACACAATCAAGCAGACAGCACCGAAGGTTGAGGGAGAAAAAGTTTTTATTGAAGTTACGGCATATCATATTATGTATGAATTTCAAAATCACTCTATTGAATCAAATAAGCTTGATGACGACAGTAGCGAATCTTCAAAAACGCCAGAATACACGTTAGAAGAGTATTTGAGATACGGATTTGCAAATCAAAAAACTTCGGTCAAAATGACCTATAAAATAATTGGAGATTTTAAGCGAAAAGTACCGATTGACGAATTAGGTAACAAAAACGGCTTAGAATACTGTAAAGAAGCGGTAGACCTGTTTGGCTGTATAATTTACCCAAATGATACAGAGATTGGTTTTTATTCTCCTGAAACATTTTATCAAAGAAGCGAGAAAGTGATTCGATATCAATATAATACTGATACTGTATCTGCAACTGTCAGTACATTGGAATTAAGAACAGCTATAAAAGTTTTTGGAAAAAAGTATACAGCTGAGGAAAAGAAAAATTATAATCCTATTAGAACAACTGACATTAAATATTCAAATGGTTTTATAAAAGAAGGTACTTATCGTACCGAAACAATTGGGTCTAAAGCTACTATTAACTTTGATTGCAAGTATGGTAATGAAACAGTTAGATTTACAATAAAAAAGGGCTCTCAAGGTGGAATATATAAGTTGATTTTAGACGGCAAGCAAATTAAGCAAATTTCTTGTTTTGCTAAGTCGGTTCAGTCTGAAACAATAGATTTAATAAAAAATATTGATAAAGGCAAGCACGTTTTAGAAATGATATTTTTAGGAGAAGACCCCAAAAATAGAATTGATATATCTTCAAATAAAAAAGCTAAGCCTTGTATGTATGTTGGAACTGAAAAATCAACAGTCTTAAATTTAATTGCTGATAATTCAGGTCGCAATCAATACAAAGCAATTGTCGACTACGTCGCAGATAGTGCAAAGCAGTTTGGGATTCGATATGCTAATACGCAAACAAATGAAGATATCGAAACACAGGATAAGCTGTTAGAATTTGCAAAAAAGCAAATAAATGATACTCCTAAGACTGAATTAGATGTTAATTATATAGGTTATGAAAAAATAGAACCAAGAGATAGCGTATTTTTTGTTCATGAATTAATGGGATATAACACTGAATTAAAGGTTGTTAAACTTGATAGGTCACATCCATTTGTAAACGCAATAGATGAAGTGTCTTTCAGCAATGAAATAAAAGATATGGTACAAATTCAACAAGCACTTAACAGACGAGTTATTGCACAAGATAATAGATATAACTATCAAGCAAATCGTATAAATCATTTATACACTAGTACTTTGAATTCTCCTTTCGAGACAATGGATATAGGGAGTGTATTAATATAA

Title	Authors	Date	PMID	Source
Efficacy of two Staphylococcus aureus phage cocktails in cheese production	El Haddad,L., Roy,J.-P., Khalil,G.E., St-Gelais,D., Champagne,C.P., Labrie,S. and Moineau,S.	2016-01	—	GenBank

Protein

Domains

Tail Spike Domain Segmentation

Taxonomy

Coding sequence (CDS)

Genome Context

Tertiary structure

Predicted Aligned Error (PAE)

Literature