Phage RBP Database

UniProt accession

A0A9E9BXA3 [UniProt]

Protein name

Tail spike protein

RBP type

TSP

Evidence DepoScope

Probability 1,00

TF

Evidence GenBank

Probability 1,00

TF

Evidence Phold

Probability 1,00

TSP

Evidence RBPdetect

Probability 0,91

TSP

Evidence RBPdetect2

Probability 0,98

TSP

Evidence UniProt/TrEMBL

Probability 1,00

Protein sequence

MALIRLVAPERVFSDLASMVAYPNFQVQDKITLLGSAGGDFTFTTTASVVDNGTVFAVPGGYLLRKFVGPAYSSWFSNWAGIVTFMSAPNRHLVVDTVLQATSVLNIKSNSTLEFTDTGRILPDAAVARQVLNIIGSAPSVFVPLAADAAAGSKVITVAAGALSVVKKGTYLYLRSNKLCDGGPNTYGVKISQIRKVVGVSTSGGVTSIRLDKALHYNYYLSDAAEVGIPTMVENVTLVSPYINEFGYDDLNRFFTIGISANFAADLHIQDGVIIGNKRPGASDIEGRSAIKFNNCVDSTVKGTYFYNIGWYGVEVLGCSEDTEVHDIHAMDVRHAISLNWQSTADGDKWGEPIEFLGVNCEAYSTTHAGFDTHDIGKRVKFVRCVSYDSADDGFQARTNGVEYLNCRAYRAAMDGFASNTGVAFPIYRECLAYDNVRSGFNCSYGGGYVYDCEAHGSQNGVRINGGRVKGGRYTRNSSSHIFVTKDVAETAQTSLEIDGVSMRYDGTGRAVYFHGTMGIDPTLVSMSNNDMTGHGLFWALLSGYTVQPTPPRMSRNLLDDTGIRGVATLVAGEATVNARVRGNFGSVANSFKWVSEVKLTRLTFPSSAGALTVTSVAQNQDVPTPNPDLNSFVIRSSNAADVSQVAWEVYL

Physico‐chemical properties

protein length:	652 AA
molecular weight:	70193,07500 Da
isoelectric point:	5,97380
aromaticity:	0,10123
hydropathy:	-0,02025

Domain architecture

A0A9E9BXA3

1 652 aa

ENZ 1–29 · STR 30–585 · ENZ 586–650 ·

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

InterPro domains

IPR057094
ENZ

IPR057094 IPR057095 IPR006626 IPR006626 IPR012334

IPR011050
STR

IPR011050 IPR056204

IPR006626
Unmapped

IPR006626 IPR006626 IPR006626

A0A9E9BXA3

1652 aa

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

Novel HMM domains (de novo, PhaRBP-HMM)

Experimental de novo families on regions without InterPro annotation. Separate from the InterPro architecture above.

DC_0267
ATT

DC_0267 DC_1484

A0A9E9BXA3

1652 aa

InterPro domain annotations

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
IPR057094	ENZ	DC_0326	1	71	InterPro cluster	K1 capsule-specific polysaccharide lyase, N-terminal domain	N-terminal	High	Text match	57 proteins / 57 hits
IPR011050	STR	IPR011050	30	487	Merged direct domain	Pectin lyase fold/virulence factor	Central	Low	Positional only	572 proteins / 572 hits
IPR057095	ENZ	DC_0534	141	231	InterPro cluster	K1 capsule-specific polysaccharide lyase, rider domain	Central	High	Text match	77 proteins / 77 hits
IPR006626	Unmapped	-	169	193	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	264	295	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	296	318	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR012334	STR	IPR012334	344	585	Merged direct domain	Pectin lyase fold	Central	Low	Positional only	867 proteins / 867 hits
IPR006626	Unmapped	-	377	399	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	445	466	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR056204	ENZ	DC_0206	564	650	InterPro cluster	K1 capsule-specific polysaccharide lyase, C-terminal domain	C-terminal	High	Text match	97 proteins / 97 hits

Proteins with similar domain architecture

Segmented into three structural domains: N-terminal, central, and C-terminal.

Domain layout

A0A9E9BXA3

1 652 aa

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	78	78	0,9867
Central domain	79	567	490	0,9946
C-terminal	568	652	84	0,9295

N-terminal Central domain C-terminal

View these domains on the 3D structure via the Color by → Tail spike option in the Tertiary structure section below.

Phage

Klebsiella phage BUCT631 [NCBI] · taxon 2996057

Uroviricota Caudoviricetes Autographivirales Slopekvirinae Drulisvirus

Host

Klebsiella pneumoniae [NCBI] · taxon 573

cellular organisms Bacteria Pseudomonadati Pseudomonadota Gammaproteobacteria Enterobacterales

Genbank protein accession

WAK45693.1 [NCBI]

Genbank nucleotide accession

OP852425 [NCBI]

CDS location

range 38886 -> 40844
strand -

CDS

ATGGCATTAATTAGATTAGTAGCTCCCGAGCGGGTGTTCTCCGACTTGGCGAGCATGGTAGCATACCCAAACTTTCAGGTGCAGGACAAGATTACCCTGCTGGGCAGTGCCGGTGGGGATTTCACCTTTACTACTACTGCGTCGGTAGTGGATAACGGAACCGTGTTTGCTGTACCCGGTGGGTACCTGCTACGTAAATTCGTGGGCCCAGCATACAGCTCCTGGTTCAGCAACTGGGCGGGCATAGTCACGTTCATGAGCGCGCCTAATAGGCACCTGGTTGTGGACACGGTCCTGCAGGCCACGAGTGTGCTCAACATCAAAAGCAACTCTACGCTAGAGTTTACCGATACCGGAAGAATCCTACCGGATGCTGCGGTTGCACGTCAAGTGCTTAATATTATCGGCTCGGCACCCTCGGTGTTCGTACCGTTAGCAGCGGATGCCGCGGCGGGCAGTAAAGTCATTACGGTGGCTGCTGGGGCTTTGTCTGTGGTAAAAAAAGGTACGTACTTGTATCTTCGCTCTAACAAGCTGTGTGATGGTGGTCCTAACACCTACGGTGTAAAGATTTCCCAGATTAGGAAAGTGGTGGGGGTTAGCACCTCCGGTGGCGTCACCAGTATTCGGCTGGATAAAGCGCTGCACTATAACTACTACCTGTCTGATGCCGCGGAAGTAGGTATCCCGACAATGGTGGAGAACGTAACCTTAGTATCCCCGTACATCAACGAGTTCGGCTACGACGATTTGAACCGGTTCTTTACTATCGGTATCTCTGCCAACTTTGCCGCGGACTTGCACATACAGGACGGAGTTATTATTGGCAACAAACGCCCGGGGGCTTCTGATATAGAAGGGCGTAGTGCTATCAAGTTCAATAACTGCGTAGACAGCACCGTTAAGGGTACGTACTTCTACAACATCGGATGGTACGGGGTAGAGGTGCTCGGCTGCTCAGAGGACACGGAAGTACACGATATCCACGCTATGGACGTACGCCACGCAATCTCTCTGAACTGGCAGAGCACTGCAGACGGGGACAAGTGGGGAGAGCCTATCGAGTTCTTAGGCGTTAACTGCGAAGCCTACAGTACAACCCATGCTGGGTTTGATACTCACGACATTGGTAAGCGTGTGAAGTTCGTTCGCTGCGTTTCATACGACAGTGCTGACGATGGATTCCAAGCGCGCACTAACGGGGTAGAGTACTTGAACTGTCGAGCTTACCGCGCAGCCATGGATGGATTCGCCTCCAACACCGGCGTAGCCTTCCCTATCTATAGGGAGTGCCTAGCTTATGACAACGTACGCTCTGGCTTTAACTGTTCGTACGGTGGTGGCTACGTTTATGACTGCGAGGCTCACGGTAGCCAGAATGGTGTGCGAATCAACGGGGGCCGTGTTAAGGGTGGTCGGTACACCCGCAACTCCAGCTCTCACATCTTCGTCACTAAGGACGTAGCTGAGACAGCGCAGACATCCCTGGAGATTGATGGCGTGAGCATGCGCTACGACGGTACCGGGAGAGCTGTGTACTTCCACGGGACTATGGGCATTGACCCTACCCTGGTATCTATGTCCAATAACGACATGACCGGTCACGGTTTGTTCTGGGCATTGCTGAGCGGCTACACTGTTCAACCTACGCCTCCGCGCATGTCCAGGAACTTACTGGATGACACAGGTATCCGTGGAGTGGCAACGCTGGTTGCTGGCGAGGCTACAGTCAACGCCCGTGTACGCGGAAACTTTGGCAGCGTAGCTAACTCCTTCAAGTGGGTGTCTGAGGTTAAGTTGACGCGGTTGACCTTTCCCTCTAGTGCTGGGGCCTTGACGGTTACTAGCGTAGCTCAGAACCAGGATGTGCCTACACCTAATCCGGACCTAAACAGCTTCGTGATTAGGAGCAGTAACGCAGCGGACGTATCCCAGGTAGCCTGGGAGGTGTATCTCTAA

	Description	Category	Evidence (source)
GO:0098015	virus tail	Cellular Component	IEA:UniProtKB-KW (UniProt)
GO:0098994	symbiont entry into host cell via disruption of host cell envelope	Biological Process	IEA:UniProtKB-KW (UniProt)
GO:0098996	symbiont entry into host cell via disruption of host cell glycocalyx	Biological Process	IEA:UniProtKB-KW (UniProt)

Protein

Domains

Tail Spike Domain Segmentation

Taxonomy

Coding sequence (CDS)

Genome Context

Gene Ontology

Tertiary structure

Predicted Aligned Error (PAE)