Phage RBP Database

Genbank accession

WPJ72062.1 [GenBank]

Protein name

tail spike protein

RBP type

TF

Evidence GenBank

Probability 1,00

TSP

Evidence DepoScope

Probability 1,00

TSP

Evidence RBPdetect

Probability 0,91

TSP

Evidence RBPdetect2

Probability 0,95

Protein sequence

MNPQFSQPKGSVSKETNKEAVARRFGCKKSEVVYAKPGQSLNGYKVIYDKITERAYALPSNLGAVTITSLTDGILVHSGGTVDLGALAVSRGEFVTLGQDFNSGFTLSVKNEVVIDGTSLYIWTGSFPKTVSSGSSVSTSGGIGTNAWQRIGASGLKQDLLDANYGSKIISTKQSITGSSLRTQFDKNSDTLSIKDFGALGDGTTDDTAAIQAALDAVAVLGKKLYAPAGVYRVGALTYQPTTQTPLVLIGDGVTNTIFRKIGSSTSAMLLVGKNPSTFFIKNCVISGITFDAVDKVSYAALQMLDCWFTELDGVLCNGGQVGLEMLTPIFVKADSVTCQNSDTGLSISYWAGESFPSSQPGVIEFNNSVFQSNSLIGVKFNDGENLILSNCAIEGNGTTPGDTSQGGVYVGANVGRFMSGTIVPGLVMRDCHLESNKGFAGVAAYSGRTLLDNVFFWEGGTNTTHDVAFDGGLYTLRNCTAASPKAGGNVYEGPVVGTGNMIIQCAMRTLSINESKTTVFNDAALVTPFVKIGGPTGPAASLTFQNSATYWEMKQLASSSFGLYNGTSLVNYCDTSGNFIPGSDNNKSNGIPSNRWSVVYAGTGSISTSDREAKQDETELSDKEREVAVKLKGLIRKYKFKDAVEEKGEDARWHVGIIAQDVKAAFEEAGLVAEEYGILCYDSWEEEPADIVVHPAQEEVTMEVPDEKGGITKIVVQPAVEEWEEVRKPARKAGSRYGVRYDELLAFIIATM

Physico‐chemical properties

protein length:	753 AA
molecular weight:	80198,19320 Da
isoelectric point:	5,02374
aromaticity:	0,08632
hydropathy:	-0,11580

Domain architecture

WPJ72062.1

1 753 aa

ATT 1–162 · STR 172–588 · RBD 596–753

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

InterPro domains

G3DSA:3.30.2020.50
ATT

G3DSA:3.30.2020.50 G3DSA:2.10.10.80 IPR012334 IPR036388

IPR040775
RBD

IPR040775 IPR011050 Coil

IPR024535
ENZ

IPR024535 cd10144

IPR030392
CHP

IPR030392

IPR030392
CHP

IPR030392

WPJ72062.1

1753 aa

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

Novel HMM domains (de novo, PhaRBP-HMM)

Experimental de novo families on regions without InterPro annotation. Separate from the InterPro architecture above.

DC_0071
STR

DC_0071

WPJ72062.1

1753 aa

InterPro domain annotations

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
G3DSA:3.30.2020.50	ATT	G3DSA:3.30.2020.50	1	93	Merged direct domain	G3DSA:3.30.2020.50	N-terminal	Low	Positional only	289 proteins / 289 hits
IPR040775	RBD	DC_0821	88	152	InterPro cluster	Tail spike TSP1/Gp66, N-terminal domain	Central	High	Text match	1281 proteins / 1285 hits
G3DSA:2.10.10.80	ATT	G3DSA:2.10.10.80	94	162	Merged direct domain	G3DSA:2.10.10.80	N-terminal	Low	Positional only	383 proteins / 383 hits
IPR012334	STR	IPR012334	172	588	Merged direct domain	Pectin lyase fold	Central	Low	Positional only	867 proteins / 867 hits
IPR011050	STR	IPR011050	189	508	Merged direct domain	Pectin lyase fold/virulence factor	Central	Low	Positional only	572 proteins / 572 hits
IPR024535	ENZ	DC_0410	193	399	InterPro cluster	Rhamnogalacturonase A/B/Epimerase-like, pectate lyase domain	Central	High	Text match	420 proteins / 426 hits
IPR036388	RBD	IPR036388	596	753	Merged direct domain	Winged helix-like DNA-binding domain superfamily	C-terminal	Low	Positional only	96 proteins / 96 hits
Coil	Unmapped	-	607	627	Coils	Coil	-	-	-	-
cd10144	CHP	DC_0088	610	753	InterPro cluster	cd10144	C-terminal	High	Text match	3502 proteins / 3959 hits
IPR030392	CHP	DC_0088	610	672	InterPro cluster	Intramolecular chaperone auto-processing domain	C-terminal	High	Text match	3502 proteins / 3959 hits
IPR030392	CHP	DC_0088	610	753	InterPro cluster	Intramolecular chaperone auto-processing domain	C-terminal	High	Text match	3502 proteins / 3959 hits

Proteins with similar domain architecture

Segmented into three structural domains: N-terminal, central, and C-terminal.

Domain layout

WPJ72062.1

1 753 aa

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	206	206	0,9901
Central domain	207	513	308	0,9870
C-terminal	514	753	239	0,9710

N-terminal Central domain C-terminal

View these domains on the 3D structure via the Color by → Tail spike option in the Tertiary structure section below.

Phage

Salmonella phage CRW-SP2 [NCBI] · taxon 3079598

Viruses Duplodnaviria Heunggongvirae Uroviricota Caudoviricetes

Host

Salmonella enterica subsp. enterica serovar Paratyphi B [NCBI] · taxon 57045

Pseudomonadota Gammaproteobacteria Enterobacterales Enterobacteriaceae Salmonella Salmonella enterica

Genbank protein accession

WPJ72062.1 [NCBI]

Genbank nucleotide accession

OR464140.1 [NCBI]

CDS location

range 30057 -> 32318
strand -

CDS

ATGAATCCGCAATTTTCTCAGCCGAAAGGCTCAGTGTCAAAAGAAACCAACAAAGAGGCCGTCGCCCGGCGTTTTGGATGTAAGAAATCCGAAGTCGTCTATGCAAAACCTGGTCAGTCCCTCAATGGCTACAAAGTGATCTATGACAAGATCACAGAACGCGCCTACGCGCTTCCTTCTAATTTGGGAGCCGTTACCATCACCAGCCTGACAGACGGCATTCTTGTTCACTCGGGGGGTACTGTTGACCTGGGTGCGCTGGCCGTATCACGTGGTGAATTTGTTACCTTGGGACAAGATTTTAATTCTGGGTTTACTCTAAGTGTGAAAAATGAAGTAGTGATCGATGGTACTTCACTTTATATTTGGACAGGTTCTTTCCCGAAAACTGTTTCTTCTGGCAGTTCTGTGTCGACTTCCGGTGGTATTGGTACGAATGCGTGGCAACGTATCGGGGCTTCTGGCCTGAAACAAGATCTGCTGGATGCAAACTACGGTTCAAAAATCATATCGACCAAACAATCAATTACTGGGTCTTCGCTCCGCACACAGTTTGACAAGAATTCAGACACCCTCAGTATTAAAGATTTTGGTGCTTTGGGTGATGGTACCACGGATGATACCGCTGCAATCCAGGCCGCTCTGGATGCCGTGGCGGTATTGGGGAAAAAACTTTACGCACCCGCTGGAGTTTACCGGGTTGGTGCCCTCACTTATCAACCAACAACTCAAACTCCTTTAGTTCTTATCGGTGATGGAGTGACCAATACCATTTTCCGTAAAATTGGTTCAAGCACTTCCGCTATGTTGTTGGTCGGTAAAAATCCTTCAACGTTTTTTATCAAGAATTGTGTCATATCTGGCATCACATTTGATGCAGTTGACAAAGTATCTTATGCTGCGTTGCAAATGCTGGATTGCTGGTTTACGGAATTGGATGGAGTTCTGTGTAACGGCGGCCAGGTTGGTTTAGAGATGTTGACACCGATCTTTGTCAAGGCTGACAGTGTTACTTGCCAAAATTCGGATACGGGTTTGAGTATTTCTTATTGGGCTGGTGAATCCTTCCCAAGTAGCCAGCCTGGTGTGATAGAATTCAACAACTCTGTTTTCCAATCAAACAGTCTGATCGGTGTTAAATTCAACGACGGGGAAAACCTGATACTGAGCAACTGCGCCATCGAAGGTAACGGTACTACTCCGGGAGACACCTCTCAAGGTGGAGTGTATGTCGGCGCTAATGTTGGTCGCTTTATGTCTGGAACGATCGTCCCCGGTTTAGTAATGCGGGATTGCCACCTTGAATCCAATAAAGGGTTTGCTGGGGTTGCGGCTTACAGCGGAAGAACTCTTTTGGATAACGTATTCTTCTGGGAAGGCGGCACGAACACCACGCATGACGTAGCATTCGATGGTGGGCTGTATACCTTGAGAAACTGTACCGCCGCTTCGCCGAAGGCTGGTGGGAACGTCTATGAAGGACCAGTCGTCGGCACAGGAAACATGATCATACAGTGTGCAATGCGCACCCTTTCGATAAATGAATCGAAAACGACTGTTTTTAATGATGCTGCGTTGGTCACTCCTTTTGTTAAGATAGGTGGTCCCACTGGTCCAGCTGCGTCTCTGACGTTCCAAAACTCAGCGACTTATTGGGAAATGAAGCAATTGGCATCTTCTTCCTTTGGTTTGTACAATGGTACTTCTCTTGTCAACTATTGTGATACTTCTGGAAACTTTATACCCGGCTCTGATAACAATAAGAGCAATGGTATCCCAAGCAATCGATGGAGTGTCGTTTATGCTGGTACAGGTTCCATCAGTACATCTGATAGAGAGGCAAAACAAGACGAGACCGAACTCTCTGATAAAGAAAGAGAAGTAGCGGTCAAGTTGAAAGGTCTAATCAGAAAGTATAAATTCAAAGATGCTGTTGAAGAGAAGGGTGAAGACGCGCGCTGGCATGTTGGTATAATTGCACAAGATGTCAAGGCCGCCTTTGAAGAAGCGGGACTTGTTGCTGAGGAATACGGCATTCTCTGCTATGATTCTTGGGAAGAAGAACCTGCCGATATCGTCGTTCACCCGGCTCAAGAAGAAGTGACGATGGAAGTACCGGACGAGAAAGGTGGGATTACCAAAATTGTTGTCCAGCCCGCTGTTGAAGAGTGGGAAGAAGTCAGAAAACCTGCTCGGAAGGCTGGATCAAGGTACGGAGTGAGATATGATGAATTGCTTGCATTCATCATAGCCACTATGTAA

Protein

Domains

Tail Spike Domain Segmentation

Taxonomy

Coding sequence (CDS)

Genome Context

Tertiary structure

Predicted Aligned Error (PAE)