Protein

View in Explore
Genbank accession
ATS92567.1 [GenBank]
Protein name
K2-ORF16
RBP type
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect
Probability 0,91
TSP
Evidence RBPdetect2
Probability 0,95
TSP
Evidence DepoCatalog
Probability 1,00
Protein sequence
MTIIKRADLGRPLTWDELDDNFQQVDDLTAAASAAVLSASASATAAAGSATNSLNSANSAASSADDAAASATVAINALMNSTFEPADFDFTSGGTLDSTDRNKAVYNPADNNWYSWSGILPKIVTAATDPTADSNWKPRTDQLLRQNLASSVIPGTSLVTHSDGIHLDDYIEIFNRRTKFIMPEDFPGTDTEQLQSALSYAKSNRVNVVLQAGKTYYVTGSQGLEVDLGYYSFESPNGIAYIDFTGCTATYCLWVHSSRPYPDGSENHCTSMRGIKFKSSVKGIGQRLLLTGNNNDSSNGTYNGDCKIENCMFSTADIVLGASNSTWRYKFINCGFMMESTGGTYAMHFPAGISDSGESVTFQNCKIFDMKGCPILVECASFAIGMPGTSVLNTPIKITGSGAMVIMDSAANIENPGASAWYRYGEVTGTGARLILNGCTLVCNNPSLQTKPLFYVGANAFIDVTLVKTPGNDYLFQNGDEGLRTFVEGDGYVTASHCIGDILSGVGNIPLHKSLNPTLNPGFETGDLSSWSFNNQGSASQTCVVGTAYKKTGTYGARMTSFGSLSCFLTQKVKVTQHGYYSTTCQINTITAGTGTTAGSLTITFYNRDGNALQAGASSNFTNTPSGWQSVGRFIQGRVPQAAEYCEVSFRCREGAVIDVDNFIINFT
Physico‐chemical
properties
protein length:668 AA
molecular weight: 71312,56740 Da
isoelectric point:4,97753
aromaticity:0,09731
hydropathy:-0,16302

Domains

Domains [InterPro]
G3DSA:2.10.10.80
83–151
G3DSA:2.10.10.80 IPR011050 G3DSA:2.60.120.260
ATS92567.1
1 668
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Klebsiella phage 1611E-K2-1
[NCBI] 		2047786 Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
ATS92567.1 [NCBI]
Genbank nucleotide accession
MG197810 [NCBI]
CDS location
range 43014 -> 45020
strand -
CDS
ATGACCATTATCAAACGCGCAGACCTGGGTCGACCCTTAACGTGGGACGAACTGGATGACAATTTCCAGCAGGTTGATGATTTGACAGCCGCCGCATCGGCGGCTGTATTGAGTGCATCGGCTTCAGCTACAGCCGCTGCGGGCAGTGCTACGAATTCACTTAATAGTGCGAATAGTGCTGCTAGTTCGGCCGATGACGCCGCAGCCTCAGCCACTGTGGCGATAAATGCGTTGATGAATTCAACATTTGAGCCCGCTGATTTCGATTTTACCAGTGGTGGGACGCTCGATAGTACCGACCGCAATAAAGCAGTGTACAACCCGGCGGACAATAACTGGTATTCATGGTCGGGCATTCTGCCAAAAATTGTAACGGCGGCCACTGACCCGACGGCGGACAGTAACTGGAAGCCGCGCACGGATCAGTTATTGCGGCAAAACCTGGCATCATCCGTGATTCCGGGGACTTCATTAGTAACCCACTCTGACGGTATACATCTCGATGATTATATAGAGATTTTTAACAGAAGAACTAAGTTTATAATGCCGGAGGATTTCCCAGGCACTGACACAGAGCAGCTCCAGTCGGCGCTATCTTATGCGAAGTCCAACAGAGTCAATGTGGTGTTACAGGCTGGGAAAACCTATTATGTAACCGGGTCGCAAGGGTTGGAAGTAGATTTAGGGTACTATTCTTTCGAGAGCCCCAATGGCATTGCCTATATTGACTTTACTGGTTGTACGGCCACTTACTGCTTGTGGGTCCATTCCAGCCGACCGTATCCTGATGGGTCGGAGAACCACTGTACATCCATGCGCGGTATAAAATTTAAAAGCTCGGTCAAAGGTATTGGTCAGCGGTTGCTGCTAACTGGAAACAATAACGATTCCAGTAACGGCACCTACAATGGTGATTGTAAGATAGAAAACTGTATGTTTTCTACCGCTGACATTGTTTTAGGGGCCTCTAACAGTACCTGGAGATACAAATTCATTAATTGCGGATTTATGATGGAGTCAACTGGAGGCACATATGCGATGCACTTCCCGGCTGGCATTTCGGACTCTGGAGAGTCAGTTACTTTCCAAAATTGCAAAATATTCGACATGAAGGGATGCCCGATACTTGTTGAGTGCGCAAGTTTTGCCATTGGGATGCCTGGCACATCGGTATTGAATACCCCAATTAAGATAACAGGTAGCGGTGCCATGGTTATCATGGATTCTGCGGCTAACATTGAAAATCCAGGCGCGTCAGCGTGGTATCGCTACGGGGAAGTAACAGGAACTGGCGCGCGGCTCATCCTTAATGGGTGTACACTTGTGTGTAACAACCCGTCGCTGCAAACGAAACCATTATTCTACGTGGGGGCAAACGCCTTCATCGATGTAACCCTTGTTAAAACACCAGGAAATGATTATCTCTTTCAGAATGGAGACGAAGGATTGAGAACTTTCGTTGAGGGAGATGGGTATGTTACCGCAAGTCATTGTATCGGTGATATCTTGTCAGGGGTGGGAAATATTCCACTCCATAAATCACTGAACCCAACATTGAATCCAGGATTTGAGACAGGGGATTTATCATCGTGGTCATTTAATAATCAGGGGTCTGCTAGTCAAACATGCGTAGTTGGTACAGCATATAAGAAAACAGGCACTTATGGTGCGAGAATGACATCGTTCGGGTCGTTAAGTTGTTTCTTAACTCAAAAGGTAAAAGTAACACAGCATGGTTATTACTCGACAACGTGTCAAATCAATACAATAACCGCGGGAACAGGAACAACAGCAGGGTCGTTAACCATTACATTTTACAATAGGGATGGTAACGCCCTCCAAGCAGGTGCAAGTAGTAATTTTACTAACACCCCGAGCGGATGGCAATCTGTAGGACGGTTCATACAGGGTCGCGTGCCACAAGCCGCTGAGTACTGCGAAGTATCTTTCCGCTGCCGTGAAGGTGCGGTGATCGACGTCGATAATTTCATTATTAATTTTACATAG

DepoCatalog

K-type Target
K2
Number of Rings

10

Structural Classification
Domain Ranges
N-terminal Domain
1-189
Central Domain
190-512
C-terminal Domain
513-668
Catalytic Information
Mechanism of Action: Hydrolase
Cleaved Bond: β-D-Glc-(1→4)-β-D-Man
Experimentally Tested K-types
K2
Phage Morphotype

Myo-type

Tertiary structure

1 / 2
PDB ID
Source
Method
Resolution
Oligomeric State

Literature

Title Authors Date PMID Source
Development of Klebsiella pneumoniae capsule polysaccharide-conjugated vaccines using phage depolymerase Lin,T.-L., Yang,F.-L., Wu,C.-Y., Wu,S.-H. and Wang,J.-T. 2022-03-21 — GenBank
Development of Klebsiella pneumoniae Capsule Polysaccharide-Conjugated Vaccine Candidates Using Phage Depolymerases Lin, Tzu-Lung; Yang, Feng-Ling; Ren, Chien-Tai; Pan, Yi-Jiun; Liao, Kuo-Shiang; Tu, I-Fan; Chang, Yu-Pei; Cheng, Yang-Yu; Wu, Chung-Yi; Wu, Shih-Hsiung 2022-01-01 — 10.3389/fimmu.2022.843183