Protein

View in Explore
Genbank accession
QJI52632 [GenBank]
Protein name
K2-2
RBP type
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect
Probability 0,91
TSP
Evidence RBPdetect2
Probability 0,94
TSP
Evidence DepoCatalog
Probability 1,00
Protein sequence
MALVDLVRAGGYSIEYPQFSSMAKLKAFPHSEDGQLVRLLSWHEGVGLGGGLFKVSTSSTATGNDGTVVVASNGVRLLRVVNGPIWADMFGALPNSDIDSMPAVVAAYAYAASVNTDLYIGVATYKFKGSTPINVDPSRAGIIGYQGKVRIDCSEFTGSVVFSINSSYSYTPAAYYNNLSPALQGLYVFGAKTSGVDGLLVGRETVGSDKSYNGQTEVRECTFDKFDRNIRMGHNSWRFVFYKVNSLNALSPNGILYVPAGLDDSGEILSFYHCQFFDGAGSNIRLSCSSYTMVFNTCSFLNITFFVDSASSATVTCNGCNFENPGSASTRRYVDISAGHTNVFNIIGGSIVTNSNPGQTQALLYVSTNNLLNLVGVTVPYGGHYQQEQELGYHAFIGGAGTVTTSGVMLQLLNGAGTCPLHSSLSTFSNWDFGYGNPNAWTVDKGTGTSSVVEYLANAGPKGTEGAMRVAPVSVGTNVSQVQAVTNPGMFSMSCMVNIATTPGNAGQISIGFLDAAGNSLPGGVSANLGTTTGWKVIGKNTLRGKVPIGAKQIRVNIQTVAGADVKYAYLLCNVVK
Physico‐chemical
properties
protein length:577 AA
molecular weight: 60816,77600 Da
isoelectric point:7,04715
aromaticity:0,10052
hydropathy:0,06794

Domains

Domains [InterPro]

No domain annotations available.

Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Klebsiella phage VLC6
[NCBI] 		2723743 Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
QJI52632 [NCBI]
Genbank nucleotide accession
QJI52632.1 [NCBI]
CDS location
range 42292 -> 44025
strand +
CDS
ATGGCACTAGTAGATTTAGTGAGGGCTGGGGGATATTCTATTGAGTACCCGCAATTCTCCAGTATGGCTAAGCTAAAAGCATTCCCACACTCTGAGGACGGGCAACTTGTTAGGTTGTTGTCTTGGCATGAGGGGGTTGGTTTAGGTGGTGGGCTGTTCAAGGTCAGCACCAGCAGCACCGCTACAGGTAACGATGGTACGGTAGTAGTGGCTAGTAATGGAGTGCGGTTGCTTCGAGTAGTAAACGGACCTATCTGGGCGGATATGTTTGGTGCACTACCGAATTCAGATATAGACAGTATGCCAGCAGTGGTTGCGGCTTATGCGTACGCTGCTTCTGTGAATACGGACTTGTATATCGGGGTGGCGACTTACAAATTCAAGGGGAGCACCCCAATTAATGTAGACCCATCCAGGGCCGGTATTATTGGTTATCAAGGTAAGGTGCGCATTGACTGCTCTGAGTTTACTGGCTCGGTTGTGTTTTCTATAAACAGCAGCTACAGCTATACCCCCGCAGCCTACTACAACAACCTTAGCCCGGCCCTGCAGGGGCTGTACGTGTTTGGTGCTAAAACGTCCGGAGTAGACGGACTACTGGTTGGTAGGGAAACAGTAGGGTCGGACAAGAGCTATAACGGGCAGACCGAGGTTCGTGAGTGCACGTTCGATAAGTTTGACCGCAACATCCGAATGGGGCACAACTCTTGGCGCTTTGTGTTCTACAAAGTAAACAGCCTAAACGCTCTCAGCCCTAACGGGATATTGTATGTACCTGCTGGACTAGATGACTCTGGGGAGATTCTGTCGTTCTACCACTGCCAGTTCTTTGACGGTGCAGGTAGTAATATCCGATTATCTTGCTCCTCGTACACTATGGTATTTAATACCTGCTCGTTCCTGAACATCACGTTCTTTGTGGATTCGGCGAGTAGTGCGACGGTAACTTGCAATGGGTGCAACTTCGAGAACCCTGGAAGTGCTAGTACCCGTAGATACGTTGACATTAGTGCTGGGCACACTAACGTATTCAACATTATCGGGGGCAGTATAGTTACAAACAGCAACCCTGGACAGACTCAGGCGCTGCTGTATGTCTCTACTAACAACCTACTGAACCTTGTAGGTGTAACTGTTCCTTACGGCGGGCATTACCAGCAGGAGCAGGAGCTCGGGTATCACGCATTCATCGGCGGGGCCGGTACAGTCACAACCTCTGGGGTTATGCTGCAGCTACTCAACGGGGCGGGTACGTGTCCTTTGCACTCCAGTCTTAGCACGTTCAGTAACTGGGATTTTGGTTATGGGAACCCGAATGCTTGGACGGTAGATAAAGGGACTGGTACATCCTCTGTGGTAGAGTATCTGGCTAATGCCGGACCTAAAGGTACAGAGGGAGCTATGCGCGTTGCCCCTGTAAGCGTCGGTACTAACGTGTCGCAAGTACAGGCAGTAACTAACCCTGGAATGTTCAGTATGTCCTGCATGGTGAATATTGCGACGACTCCCGGTAACGCAGGGCAGATATCTATTGGGTTCTTGGATGCTGCTGGTAACAGTCTGCCTGGTGGGGTCTCGGCTAACCTGGGCACCACCACGGGTTGGAAGGTAATCGGCAAGAACACCCTGCGTGGCAAAGTCCCAATCGGTGCTAAGCAGATTCGTGTGAACATCCAGACTGTGGCTGGCGCAGACGTTAAGTACGCGTACTTGCTGTGCAATGTGGTCAAGTAA

DepoCatalog

K-type Target
K2
K13
Number of Rings

10

Structural Classification
Domain Ranges
N-terminal Domain
1-99
Central Domain
100-416
C-terminal Domain
417-577
Catalytic Information
Mechanism of Action: Hydrolase (retaining)
Catalytic Amino Acids: Glu267, Glu323
Catalytic Site Location: Inter-subunit
Cleaved Bond: β-D-Glc-(1→4)-β-D-Man
Experimentally Tested K-types
K1-K82
Phage Morphotype

Podo-type

Tertiary structure

1 / 5
PDB ID
Source
Method
Resolution
Oligomeric State

Literature

Title Authors Date PMID Source
<i>Klebsiella pneumoniae</i> K2 capsular polysaccharide degradation by a bacteriophage depolymerase does not require trimer formation Ye, Ting-Juan; Fung, Kit-Man; Lee, I-Ming; Ko, Tzu-Ping; Lin, Chia-Yi; Wong, Chia-Ling; Tu, I-Fan; Huang, Tzu-Yin; Yang, Feng-Ling; Chang, Yu-Pei 2024-01-01 — 10.1128/mbio.03519-23