Protein

View in Explore
Genbank accession
YP_009797016.1 [GenBank]
Protein name
K64-ORF41
RBP type
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect
Probability 0,91
TSP
Evidence RBPdetect2
Probability 0,95
TF
Evidence Phold
Probability 1,00
TSP
Evidence DepoCatalog
Probability 1,00
Protein sequence
MDQDTKTIIQYPTSGDEYDIPFDYLSRKFVRVSLVSNTQRVLLDNITDYRYVSRTRVKLLVSTDGYSRVEIRRFTSASEMVVDFSDGSVLRATDLNVSALQSAHIAEEARDLFSTSLSIGQLSYFDAKGLQIKNVAAGVDNTDAVTVQQLNKIIADVVTTIPDSVADNIRGLWARVLGDIGITLVDGSFETGATITTRTQALWSISGRKCYTWAGALPKVVPENSTPESTGGISETAWVDSSSKALGVLLAGPSGAERVGLKQGGTVQDAINWLTFDSFDIVKDGSKDVTADIMAACVVANDLGLDIKQNDGTYLVSGNPVWPVYNSLDLNGVTLKLAAGFTGYFALTQKDSTTVYGPTSPIVQAINAAGGRTAGSGVLEGLVNSTELNGKFLFMEGADVLYYSRGTAKYWWTNTYLSNRGKLSDNLKYGVSAITKITAVTPRTKIVYYRLPNLDFGNGPANNGVIRVLNNTRFIMQGGSISNRPLKDVSKSPVIISLNYCAAFKAYDFFDPYPAFAVDSNNSLVYSYTLNFNDIADAVFENFNSQGYGWGVVGGQRSTNITYRDCNLNRVDMHNPYMGYLKVLDTRLGTWGINASGMGDMYLERVTVDLDDSAHGGHREHEGIINARGDFGGFHDGGLYIKDLTIVGEASAFEATSGHPVALVSAYSFNASLAYIPESSPVTPWGFKEVIVEGLHCPFKRTGRRFNSIISAPSIQFTVYHPMRVKLEDCNFNSTAFEKFDLRGWRVTPYNPSKVGIANTLAFRPTNFVDVKDCSMVGLEFTRPTSAYDYSNFDVNLVNVKNVEEHSLSPFTLYTNQCGRYNLVGCGLQQIVDKSMTSGERANRRSTFSVTGGTWNSLSGNPTDITYGNGYDIPVVATGVMFVGPYSQTEVTGANLNVAEFVQASGCKFLSSGPTYIQPLLWSGAGGPTGASANFNVARGNTLGLNISAVNGETSQVIAATLVIPQGFSTGPAAGTTYGFAVEKNINYQLGLNARSLKANVGLVRCSDTITGVYLNA
Physico‐chemical
properties
protein length:1017 AA
molecular weight: 109986,19210 Da
isoelectric point:5,66306
aromaticity:0,10226
hydropathy:-0,09872

Domains

Domains [InterPro]
IPR005604
6–126
IPR005604 IPR008635 G3DSA:2.10.10.80
IPR011049
72–155
IPR011049 IPR040775
IPR011049
116–153
IPR011049
YP_009797016.1
1 1017
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Klebsiella phage SH-Kp 152410
[NCBI] 		2066504 Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
YP_009797016.1 [NCBI]
Genbank nucleotide accession
NC_047908.1 [NCBI]
CDS location
range 33513 -> 36566
strand +
CDS
ATGGACCAAGATACTAAAACAATCATCCAATACCCCACCAGTGGTGACGAATATGATATCCCCTTTGACTACCTGTCGCGTAAGTTTGTCCGTGTGTCTCTCGTATCGAATACCCAGCGCGTCTTACTGGATAACATCACAGATTACCGTTACGTCTCCAGAACGCGCGTCAAGCTGCTTGTAAGTACCGATGGGTATAGCCGTGTAGAGATTCGACGCTTCACCTCTGCGTCCGAGATGGTCGTGGACTTCAGCGATGGGTCCGTTCTCCGCGCGACCGACCTTAACGTGTCCGCTCTACAGTCTGCACACATCGCAGAGGAGGCTCGTGACTTATTCAGCACATCCCTGAGCATTGGCCAACTTAGCTACTTTGACGCTAAAGGCTTGCAGATAAAGAATGTAGCAGCAGGTGTTGACAATACCGATGCAGTAACCGTTCAGCAGCTCAACAAGATAATCGCTGACGTCGTGACCACCATCCCTGACAGTGTGGCAGATAACATCCGGGGCCTTTGGGCGCGAGTTTTAGGTGACATCGGAATCACGCTTGTTGACGGTAGCTTCGAGACTGGTGCAACCATTACTACCAGAACTCAAGCACTGTGGTCCATAAGTGGCCGTAAGTGCTATACATGGGCTGGTGCTCTGCCTAAGGTTGTCCCAGAGAACTCTACCCCAGAGTCTACAGGCGGTATTTCCGAAACGGCGTGGGTGGATAGTTCCTCCAAGGCCCTCGGTGTACTTTTGGCTGGACCATCTGGAGCTGAGCGCGTCGGTCTCAAGCAGGGCGGTACCGTTCAGGACGCCATTAATTGGTTGACGTTCGACTCCTTCGACATCGTAAAGGATGGTTCAAAAGATGTCACGGCAGATATTATGGCAGCCTGCGTTGTAGCCAACGACCTCGGGCTGGACATTAAGCAGAACGATGGGACATACCTAGTGTCTGGGAACCCTGTGTGGCCTGTGTACAACTCTCTTGACCTCAACGGTGTGACGCTGAAGTTGGCTGCCGGTTTCACTGGGTACTTCGCCCTGACCCAGAAAGACTCCACAACGGTTTACGGACCAACCAGTCCTATCGTTCAGGCCATCAATGCGGCTGGTGGGCGAACCGCTGGTTCAGGGGTTTTGGAAGGTCTGGTGAACTCTACCGAGCTGAATGGGAAGTTCCTGTTCATGGAGGGGGCCGATGTGCTTTACTACTCCCGAGGAACCGCGAAGTATTGGTGGACGAACACCTACCTGTCAAACCGTGGGAAACTGAGCGACAACCTTAAGTATGGTGTGTCGGCTATCACGAAGATAACTGCGGTTACCCCGCGAACGAAGATTGTCTACTACCGTCTACCAAATCTGGACTTTGGTAACGGCCCTGCAAACAACGGTGTGATTCGCGTACTGAACAACACCCGGTTCATTATGCAAGGCGGCTCAATCTCCAACCGTCCACTTAAGGATGTGTCAAAGAGTCCGGTCATAATCAGCCTCAACTACTGTGCAGCCTTCAAGGCGTACGACTTCTTCGACCCCTATCCGGCCTTTGCGGTGGATTCCAATAACTCACTCGTCTACTCCTACACCCTGAACTTCAACGACATCGCTGACGCTGTGTTTGAGAACTTCAACTCTCAGGGATATGGTTGGGGTGTGGTTGGCGGACAGCGCTCTACCAACATAACCTATCGTGACTGTAACCTTAACAGGGTGGATATGCACAACCCTTACATGGGGTACCTGAAGGTTCTGGACACCCGCTTGGGTACTTGGGGTATCAATGCTTCAGGCATGGGTGATATGTACTTGGAGCGCGTCACGGTCGATTTGGACGATTCGGCACATGGCGGCCACCGAGAGCACGAGGGCATCATTAACGCTCGTGGTGACTTTGGCGGGTTCCATGATGGTGGTCTGTACATTAAGGACCTGACAATCGTCGGCGAGGCTTCCGCATTCGAGGCAACATCTGGACACCCAGTGGCGCTGGTCTCTGCGTACTCCTTCAACGCATCCCTTGCGTATATCCCCGAGTCCTCTCCGGTTACGCCGTGGGGCTTCAAGGAGGTAATCGTTGAGGGACTGCACTGCCCGTTCAAGCGGACTGGTCGTCGGTTCAACTCTATCATCTCCGCCCCAAGTATTCAGTTCACTGTGTATCACCCGATGCGGGTTAAACTGGAGGACTGTAACTTCAACTCTACGGCGTTCGAGAAGTTCGACCTGAGGGGCTGGAGGGTTACTCCGTACAACCCCTCGAAGGTTGGTATCGCGAACACTCTGGCATTCCGTCCTACGAACTTTGTTGATGTGAAGGACTGCTCGATGGTTGGCCTTGAGTTCACCCGACCGACTAGTGCATACGACTACTCTAACTTTGACGTAAACCTCGTTAACGTTAAGAATGTAGAGGAACACTCCCTGTCGCCGTTCACTCTGTACACTAACCAGTGTGGTCGTTATAACTTGGTTGGGTGCGGTCTGCAACAGATTGTGGACAAGTCGATGACCTCGGGTGAGCGCGCAAACCGTCGGAGCACGTTCTCGGTGACTGGCGGTACTTGGAACTCACTTTCCGGTAACCCTACGGATATAACCTACGGTAACGGCTACGACATCCCTGTGGTGGCGACTGGTGTTATGTTCGTTGGTCCGTACTCCCAGACTGAAGTGACAGGCGCAAACTTGAACGTTGCAGAGTTTGTTCAGGCATCCGGCTGCAAGTTCCTCAGTTCCGGCCCGACCTACATCCAGCCGTTACTCTGGAGTGGTGCAGGTGGTCCAACTGGAGCGAGTGCTAACTTCAACGTGGCACGCGGGAACACTCTGGGCCTGAACATCTCTGCGGTGAACGGTGAGACGTCTCAGGTTATCGCGGCGACTCTGGTGATTCCGCAAGGGTTCTCAACTGGACCGGCTGCTGGTACAACCTACGGGTTCGCCGTGGAAAAGAACATCAACTACCAATTAGGGCTTAACGCCCGCAGCCTGAAGGCGAACGTTGGTTTAGTGCGTTGTAGTGATACCATAACCGGGGTGTACCTGAACGCATAA

DepoCatalog

K-type Target
K64
Number of Rings

16

Structural Classification
Domain Ranges
N-terminal Domain
1-287
Central Domain
288-919
C-terminal Domain
920-1017
Catalytic Information
Mechanism of Action: Lyase (beta elimination)
Catalytic Amino Acids: Tyr528, His574, Arg628
Catalytic Site Location: Intra-subunit
Experimentally Tested K-types
K64
Phage Morphotype

Podo-type

Tertiary structure

1 / 4
PDB ID
Source
Method
Resolution
Oligomeric State

Literature

Title Authors Date PMID Source
Complete genome sequence of bacteriophage SH-Kp 152410 with lytic activity against Klebsialla pneumoniae Xu,M., Wang,R., Hu,F. and He,P. 2014-08-27 — GenBank
Identification of a Depolymerase Specific for K64-Serotype Klebsiella pneumoniae: Potential Applications in Capsular Typing and Treatment Li, Jiayin; Sheng, Yueying; Ma, Ruijing; Xu, Mengsha; Liu, Fuli; Qin, Rong; Zhu, Mingxi; Zhu, Xianchao; He, Ping 2021-01-01 — 10.3390/antibiotics10020144