Protein

UniProt accession

U5PW80 [UniProt]

Protein name

Endolysin

RBP type

evidence: GenBank

probability: 1,0000

evidence: Phold

probability: 1,0000

evidence: RBPdetect

probability: 0,8669

Protein sequence

MTSTSTETLKNKGTAVKGGLANAQPGDLIFFDTYKKNGHVVIYLGNNQFIGAQGKTGVGIVDLNSSYGSYFKKRFSGNIRRIAGGGNVGAALGGGGAAMSGAGTGTAYRQAPSNLMGPINNAAKQYGVNPNLIAAIIKKESTFKSGLTSSAGAKGYMQLMPATARAMGVKNPWDTQQNINGGTKYIAQQLKTYKNNIPLALAAYNWGPGNLNKAIRKAGGSKDWNQIRRFAPKETRDYVDKIMGWR

Physico‐chemical properties

protein length:	246 AA
molecular weight:	26092,40690 Da
isoelectric point:	10,23353
aromaticity:	0,08943
hydropathy:	-0,43293

Domains

Domains [InterPro]

IPR000064
1–82

IPR000064 IPR023346

IPR038765
10–81

IPR038765 IPR008258

IPR000064
11–77

IPR000064

U5PW80

1 246

Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Domains [InterPro]

InterPro ID	Start	End	Source	Name
IPR000064	1	82	PROSITE	Endopeptidase, NLPC/P60 domain
IPR038765	10	81	SUPFAM	Papain-like cysteine peptidase superfamily
IPR000064	11	77	PROSITE	Endopeptidase, NLPC/P60 domain
IPR023346	109	244	SUPFAM	Lysozyme-like domain superfamily
IPR008258	119	226	Pfam	Transglycosylase SLT domain 1

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Bacillus phage Pony [NCBI]	1406789	Uroviricota > Caudoviricetes > Pagevirus >
Host	Bacillus megaterium [NCBI]	1404	Bacteria > Firmicutes > Bacilli > Bacillales > Bacillaceae > Bacillus

Coding sequence (CDS)

Genbank protein accession

AGY48260.1 [NCBI]

Genbank nucleotide accession

KF669660 [NCBI]

CDS location

range 19094 -> 19834
strand +

CDS

TTGACCAGCACTTCAACAGAGACATTGAAAAATAAGGGAACGGCAGTAAAGGGCGGTCTTGCTAACGCTCAACCCGGAGACTTAATTTTCTTTGATACATACAAGAAAAATGGTCACGTTGTTATTTATCTCGGAAACAATCAGTTCATTGGTGCTCAGGGTAAAACAGGTGTCGGCATTGTTGATTTAAACAGCTCATACGGTAGTTACTTTAAAAAGCGTTTTAGCGGAAATATTCGCCGTATCGCAGGCGGCGGAAACGTTGGGGCTGCTCTAGGTGGCGGCGGTGCTGCCATGAGTGGAGCGGGTACAGGTACGGCATATAGGCAAGCGCCTTCTAACTTAATGGGCCCGATTAATAACGCGGCTAAACAATACGGCGTAAACCCTAACTTAATTGCTGCTATTATTAAGAAAGAATCAACGTTTAAAAGCGGCTTGACTTCTTCTGCTGGTGCTAAGGGCTACATGCAATTAATGCCTGCTACCGCTCGTGCTATGGGAGTTAAAAACCCCTGGGATACTCAGCAAAATATTAACGGCGGTACAAAGTATATAGCGCAGCAGCTTAAAACTTACAAGAATAACATACCTCTAGCGTTAGCAGCGTACAATTGGGGACCGGGTAACTTGAATAAAGCTATTCGTAAAGCCGGAGGAAGCAAAGATTGGAATCAAATTCGCCGCTTTGCTCCAAAAGAAACGCGTGATTATGTAGATAAAATTATGGGTTGGAGGTAG

Gene Ontology

	Description	Category	Evidence (source)
GO:0008234	cysteine-type peptidase activity	Molecular Function	IEA:UniProtKB-KW (UniProt)
GO:0001897	symbiont-mediated cytolysis of host cell	Biological Process	IEA:UniProtKB-ARBA (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID: 35300

Method: ESMFold

Resolution: 0,8907

Evidence: 0,9412

Literature

No literature entries available.