Protein

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Genbank accession
QBX28549.1 [GenBank]
Protein name
hyaluronate lyase
RBP type
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect2
Probability 0,96
Protein sequence
MSKEVASARIQHRGMSTQEWETSSDILIEREIGIDTTTGYPKVGDGKNKFKDLKDLRGPMGPQGPTGERGPIGPTGPIGKTGTTDYNQLQNKPDLGAFAQKEETNSKITKLESSKADKNAVYLKAESKIELNKKLSLTGGTVTGQLRLKPNSGIDKSSSTGGAINIDMSKSKGAAMVMYTNKDTTDGPLMILRSNKDTFDQSVQFVDYKGTTNAVNIVMRQPSTPNFSSALNITSANEGGSAMQIRGVEKALGMLKITHENPNVKANYDENAAALSIDIVKKTNGEGTAAQGIYINSSTGTTGKMLRIRNKNEDKFYVGPDGGFHSGANSTVTGNLTVKDPTSEKHAATKKYVDEKIAELKKLIQKTD
Physico‐chemical
properties
protein length:368 AA
molecular weight: 39530,04850 Da
isoelectric point:9,28939
aromaticity:0,04620
hydropathy:-0,69076

Domains

Domains [InterPro]
SSF69349
STR
8–365
SSF69349
IPR041352
ATT
10–47
IPR041352 G3DSA:1.20.5.320 IPR009860
QBX28549.1
1 368
Architecture
ATT
STR
ATT 8-47 | STR 48-365 |
Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout
N-terminal
Central
C-terminal
QBX28549.1
1 368
Domain Start End Length (AA) Confidence
N-terminal 1 141 141 0,9737
Central domain 142 340 200 0,1187
C-terminal 341 368 27 0,9829
Legend: N-terminal Central domain C-terminal
3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring
N-terminal
1-141
Central
142-340
C-terminal
341-368

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptococcus phage Javan456
[NCBI] 		2548179 Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host Streptococcus pyogenes
[NCBI] 		1314 cellular organisms > Bacteria > Bacillati > Bacillota > Bacilli > Lactobacillales

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
QBX28549.1 [NCBI]
Genbank nucleotide accession
MK448946 [NCBI]
CDS location
range 36129 -> 37235
strand +
CDS
ATGTCAAAAGAAGTTGCATCAGCAAGGATACAGCATAGAGGCATGTCCACGCAAGAGTGGGAAACAAGTTCCGATATCTTAATAGAGCGAGAAATTGGAATTGACACGACTACGGGTTACCCAAAAGTTGGCGATGGTAAAAATAAGTTCAAGGACTTAAAAGACTTGCGTGGTCCTATGGGACCTCAAGGTCCTACAGGAGAAAGAGGCCCAATTGGCCCAACAGGTCCGATTGGCAAGACTGGAACGACAGATTATAATCAACTCCAAAATAAACCAGATCTAGGTGCGTTTGCACAAAAAGAAGAAACTAATAGTAAAATCACCAAATTAGAATCAAGCAAAGCAGATAAAAACGCTGTTTACTTAAAAGCAGAGTCAAAAATAGAGCTAAACAAAAAATTGAGTTTGACAGGCGGCACAGTGACAGGACAACTACGGCTTAAACCTAATAGTGGTATTGATAAGTCATCTTCTACAGGAGGAGCGATTAACATTGATATGTCTAAATCGAAAGGTGCTGCTATGGTGATGTATACAAATAAAGATACTACTGATGGACCATTGATGATTTTACGCTCTAACAAAGATACGTTTGATCAGTCAGTTCAATTTGTCGATTATAAGGGAACAACAAATGCCGTTAATATTGTGATGCGCCAGCCGAGCACACCTAATTTTTCCTCGGCACTTAATATAACCAGTGCCAACGAAGGCGGTAGTGCGATGCAAATTAGAGGCGTTGAAAAAGCATTGGGAATGCTAAAAATTACTCACGAAAACCCAAACGTTAAGGCAAATTACGATGAAAACGCTGCAGCGTTATCCATTGATATTGTCAAAAAGACAAACGGTGAAGGAACAGCCGCTCAAGGAATCTACATCAATTCCTCCACAGGAACAACTGGTAAAATGCTCAGAATCAGAAATAAAAATGAAGACAAATTTTATGTAGGTCCAGATGGCGGCTTTCACTCAGGTGCAAATTCAACTGTAACTGGTAATCTAACAGTTAAAGATCCAACATCTGAAAAACATGCTGCGACTAAAAAATACGTAGATGAAAAAATTGCTGAGTTAAAAAAACTCATACAAAAAACAGATTAA

Genome Context

Genome Context

Tertiary structure

PDB ID
06467fc8b048f177fb1b77845cfb173e1e5a1605c53030d9cea73696d31b9ae1
ESMFold
Source ESMFold
Method ESMFold
Resolution 0,7371
Oligomeric State monomer
Download PDB
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50

Literature

Title Authors Date PMID Source
Prophages and satellite prophages are widespread among Streptococcus species and may play a role in pneumococcal pathogenesis Rezaei Javan,R., Ramos-Sevillano,E., Akter,A., Brown,J. and Brueggemann,A.B. 2018-12-20 — GenBank