Protein

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Genbank accession
QBX29217.1 [GenBank]
Protein name
hyaluronate lyase
RBP type
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect2
Probability 0,96
Protein sequence
MSENIPLRVQFKRMTASEWARSDVILLESEIGFETDTGFARAGDGHNRFSDLGYISPLDYNLLTNKPNIDGLATKVETAQKLQQKADKETVYTKAESKQELDKKLNLKGGVMTGQLKFKPAATVAYSSSTGGAVNIDLSSSRGAGVVVYSNNDTSDGPLMSLRTGKETFNKSALFVDYSGKTNAVNIAMRQPSTPNFSSALNITSGNENGSAMQLRGSERALGTLKITHENPSLEANYDKDAAALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLNDDKFYVKPDGGFYAKETSQIDGNLKLKDPIANDHAATKAYVDGEVEKLKALLTAKQM
Physico‐chemical
properties
protein length:340 AA
molecular weight: 36680,80140 Da
isoelectric point:9,01108
aromaticity:0,06471
hydropathy:-0,51794

Domains

Domains [InterPro]
SSF69349
STR
7–335
SSF69349
IPR041352
ATT
9–45
IPR041352 IPR009860
QBX29217.1
1 340
Architecture
ATT
STR
ATT 7-45 | STR 46-335 |
Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout
N-terminal
Central
C-terminal
QBX29217.1
1 340
Domain Start End Length (AA) Confidence
N-terminal 1 113 113 0,9917
Central domain 114 312 200 0,1074
C-terminal 313 340 27 0,9902
Legend: N-terminal Central domain C-terminal
3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring
N-terminal
1-113
Central
114-312
C-terminal
313-340

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptococcus phage Javan486
[NCBI] 		2548201 Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host Streptococcus pyogenes HSC5
[NCBI] 		1336746 Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus > Streptococcus pyogenes

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
QBX29217.1 [NCBI]
Genbank nucleotide accession
MK448958 [NCBI]
CDS location
range 31988 -> 33010
strand +
CDS
ATGAGTGAAAATATACCGCTGCGAGTCCAATTTAAGCGGATGACTGCTAGCGAGTGGGCTCGTAGTGATGTCATCTTACTGGAGAGTGAGATAGGCTTTGAGACAGACACAGGTTTTGCCAGAGCAGGTGATGGCCACAATCGATTTAGTGACCTTGGATACATTAGCCCACTCGATTACAATCTACTGACTAACAAGCCAAATATCGATGGATTAGCGACAAAAGTCGAGACCGCTCAGAAACTACAACAAAAAGCAGATAAAGAGACCGTCTATACAAAAGCTGAATCGAAGCAAGAGCTTGACAAGAAATTAAATCTCAAAGGTGGCGTTATGACAGGTCAACTAAAATTTAAGCCAGCCGCCACTGTTGCTTATTCCTCGTCAACGGGTGGGGCGGTCAATATTGACTTGTCGTCTAGCAGAGGTGCTGGTGTTGTTGTCTATTCTAACAATGATACCAGTGATGGGCCGCTAATGAGCTTGCGGACGGGTAAAGAGACCTTCAATAAATCGGCGCTTTTTGTCGATTACAGCGGTAAGACTAATGCCGTTAATATTGCGATGCGCCAGCCAAGCACACCTAATTTTTCCTCTGCGCTTAATATTACTAGCGGCAATGAAAATGGTAGTGCGATGCAGCTACGAGGGTCAGAAAGAGCGCTAGGAACGCTAAAAATTACTCATGAGAACCCAAGTCTTGAAGCGAATTATGATAAAGATGCGGCAGCGTTATCTATTGATATCGTTAAAAAACAGAAAGGCGGAAAAGGTACTGCTGCTCAAGGAATCTACATTAACTCAACATCAGGCACGACAGGGAAGTTGCTTAGGATTAGAAACCTTAATGATGATAAGTTCTACGTCAAGCCTGACGGTGGTTTTTATGCCAAGGAAACTTCGCAGATTGATGGCAACCTGAAACTCAAGGATCCCATAGCGAATGATCATGCGGCAACCAAAGCTTATGTTGATGGTGAAGTCGAAAAATTAAAAGCACTCTTAACGGCTAAGCAAATGTAA

Genome Context

Genome Context

Tertiary structure

PDB ID
40dd48463bccebd9349912f04aefd61c8885e186ccf593b5f249927eaa8b46c4
ESMFold
Source ESMFold
Method ESMFold
Resolution 0,7656
Oligomeric State monomer
Download PDB
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50

Literature

Title Authors Date PMID Source
Prophages and satellite prophages are widespread among Streptococcus species and may play a role in pneumococcal pathogenesis Rezaei Javan,R., Ramos-Sevillano,E., Akter,A., Brown,J. and Brueggemann,A.B. 2018-12-20 — GenBank