Protein

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Genbank accession

ADA82322.1 [GenBank]

Protein name

tail spike protein

RBP type

TSP

Evidence UniProt/TrEMBL

Probability 1,00

Evidence Phold

Probability 1,00

TSP

Evidence DepoScope

Probability 1,00

TSP

Evidence RBPdetect

Probability 0,90

TSP

Evidence RBPdetect2

Probability 0,95

Protein sequence

MSSGCGDVLSLADLQTAKKHQIFEAEVITGKSGGVAGGADIDYATNQVTGQTQKTLPAVLRDAGFKLADFDFTSGGTLSANDRNTAVLWPSSSGGDGDWYYWLGALPKTIPASSSPQSTGGVSEGAWQRAGSVVLRQQISNANGAILYPDLHVARWKDEYDPRAWGAVGDGVTDDTQSIFNVLAASPNNWIIDGRGLTYKVSQLPDISKFKNAAFVYERVAGQPLTYVADGFFNSSLTKVTDTPFYNAWTQDKTFVYDNVIYAPFMAGERHGVQNLHVAWVRSGDDGQTWSMPEWLTPIHADYNASVSADRVNYHCMSMGTCGNRLYAVIETRYLSNMRMKKAELWSRPMPYFRHPTGGIAISSGSTTATIVIENHGLKAGDAVNFSNTSATGVSGNMTVASIINRNTFTVTLSSPASSTINNAGVTWNFATRFWDSPWEITELPGVAYSANADLCVTETHSFAVIDDVNYTIAVGYHNGDVPPRRLGVLYFSNVYDNPGVFVRRTVAQAYADNASEPCVKSYDGVLYLTTRGTLPTSPGSTLAMSTDSGQNWSYLRFPNNVHHSNLPFAKVGDYLYIFGTERAFGEWEGGEPDSRYEGSYPRTFMCKVNVSSWPPSLDDVQWFNITDQIYQGHIVNTAVGVGSVCVKDGWLYYIFGGEDFFSPWSIGDNSAKLWYKHDGHPADLYSYRIKIEDHPYVSRDFKYGATPNRTLPVAMGVDGVRHVGAPLTFDNDVSVYSLHVTGLEYDGTQQSAVRAQFDGDYGLISKTVPTKTPSGQRLIVSGGDGASSSDGALLQLYGANHAMPNRAIMYASGGFYSYNNFLPYLDSQVSLGSAGNRWTTVYATTGTINTSDGTLKTNKEEIEGQLLTAWEDIHVISFKWLESLAIKGDTARIHFGVIAQDVRDILVNHGLMEKDSTDCKYAFLCYDPIEAAYDIDEDGQTVQVSPPGGRWGVRADQMFFIEIAYQRKKMREFEKRLAALEDK

Physico‐chemical properties

protein length:	984 AA
molecular weight:	107971,89020 Da
isoelectric point:	5,26411
aromaticity:	0,11789
hydropathy:	-0,29096

Domains

Domains [InterPro]

DC_0055
ATT
1–190

DC_0055 G3DSA:2.120.10.10 IPR024430 cd10144

G3DSA:2.10.10.80
ATT
65–142

G3DSA:2.10.10.80 G3DSA:3.30.750.60 IPR024428 IPR044914 IPR036388

IPR040775
RBD
97–131

IPR040775 IPR036278 SSF69349 IPR030392 Coil

IPR024429
ENZ
167–233

IPR024429 IPR001724 IPR001724 IPR024427 IPR001724 IPR001724 IPR001724 IPR001724 IPR001724 IPR030392

IPR023366
STR
354–434

IPR023366

IPR001724
Unmapped
425–448

IPR001724

ADA82322.1

1 984

Architecture

ATT

STR

RBD

ATT 1-232 | STR 233-851 | RBD 852-984

Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Domains [InterPro]

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
DC_0055	ATT	DC_0055	1	190	Novel HMM	DC_0055	N-terminal	Low	Positional only	56 proteins / 56 hits
G3DSA:2.10.10.80	ATT	G3DSA:2.10.10.80	65	142	Merged direct domain	G3DSA:2.10.10.80	N-terminal	Low	Positional only	383 proteins / 383 hits
IPR040775	RBD	DC_0821	97	131	InterPro cluster	Tail spike TSP1/Gp66, N-terminal domain	Central	High	Text match	1281 proteins / 1285 hits
G3DSA:3.30.750.60	ATT	G3DSA:3.30.750.60	161	232	Merged direct domain	G3DSA:3.30.750.60	N-terminal	Low	Positional only	2 proteins / 2 hits
IPR036278	STR	IPR036278	166	698	Merged direct domain	Sialidase superfamily	Central	Low	Positional only	56 proteins / 56 hits
IPR024429	ENZ	DC_0802	167	233	InterPro cluster	Endosialidase, N-terminal extension domain	N-terminal	High	Text match	84 proteins / 84 hits
G3DSA:2.120.10.10	STR	G3DSA:2.120.10.10	233	692	Merged direct domain	G3DSA:2.120.10.10	Central	Low	Positional only	42 proteins / 42 hits
IPR024428	ENZ	DC_0114	234	693	InterPro cluster	Endosialidase, beta-propeller domain	Central	High	Text match	92 proteins / 92 hits
IPR001724	Unmapped	-	235	259	InterPro	Glycosyl hydrolase 58	-	-	-	-
IPR001724	Unmapped	-	306	334	InterPro	Glycosyl hydrolase 58	-	-	-	-
IPR024427	ENZ	DC_0382	351	433	InterPro cluster	Endosialidase, beta-barrel domain	Central	High	Text match	86 proteins / 86 hits
IPR023366	STR	IPR023366	354	434	Merged direct domain	ATP synthase subunit alpha, N-terminal domain-like superfamily	Central	Low	Positional only	44 proteins / 44 hits
IPR001724	Unmapped	-	425	448	InterPro	Glycosyl hydrolase 58	-	-	-	-
IPR001724	Unmapped	-	504	530	InterPro	Glycosyl hydrolase 58	-	-	-	-
IPR001724	Unmapped	-	582	608	InterPro	Glycosyl hydrolase 58	-	-	-	-
IPR001724	Unmapped	-	640	664	InterPro	Glycosyl hydrolase 58	-	-	-	-
IPR024430	ENZ	DC_0521	694	851	InterPro cluster	Endosialidase, C-terminal domain	C-terminal	High	Text match	95 proteins / 95 hits
IPR044914	RBD	IPR044914	695	851	Merged direct domain	Endosialidase, C-terminal domain superfamily	C-terminal	Low	Positional only	39 proteins / 39 hits
SSF69349	STR	SSF69349	699	851	Merged direct domain	SSF69349	Central	Low	Positional only	153 proteins / 153 hits
IPR001724	Unmapped	-	744	770	InterPro	Glycosyl hydrolase 58	-	-	-	-
IPR001724	Unmapped	-	776	803	InterPro	Glycosyl hydrolase 58	-	-	-	-
cd10144	CHP	DC_0088	852	970	InterPro cluster	cd10144	C-terminal	High	Text match	3502 proteins / 3959 hits
IPR036388	RBD	IPR036388	852	980	Merged direct domain	Winged helix-like DNA-binding domain superfamily	C-terminal	Low	Positional only	96 proteins / 96 hits
IPR030392	CHP	DC_0088	852	912	InterPro cluster	Intramolecular chaperone auto-processing domain	C-terminal	High	Text match	3502 proteins / 3959 hits
IPR030392	CHP	DC_0088	852	984	InterPro cluster	Intramolecular chaperone auto-processing domain	C-terminal	High	Text match	3502 proteins / 3959 hits
Coil	Unmapped	-	964	984	Coils	Coil	-	-	-	-

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout

N-terminal

Central

C-terminal

ADA82322.1

1 984

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	176	176	0,9934
Central domain	177	511	336	0,8603
C-terminal	512	984	472	0,5779

Legend: N-terminal Central domain C-terminal

3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring

N-terminal
1-176

Central
177-511

C-terminal
512-984

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Escherichia phage K1H [NCBI]	698487	Uroviricota > Caudoviricetes > Sarkviridae > Kagunavirus > Kagunavirus K1H
Host	Escherichia coli [NCBI]	562	cellular organisms > Bacteria > Pseudomonadati > Pseudomonadota > Gammaproteobacteria > Enterobacterales

Coding sequence (CDS)

No CDS data available.

Genome Context

Tertiary structure

PDB ID

9fcb8282f20479724db67092e91483f29a335b4a762544ed5a26486d0ea8af86

ESMFold

Source ESMFold

Method ESMFold

Resolution 0,6451

Oligomeric State monomer

Download PDB

Model Confidence

Very high
pLDDT > 90

High
90 > pLDDT > 70

Low
70 > pLDDT > 50

Very low
pLDDT < 50

Protein

Domains

Domains [InterPro]

Domains [InterPro]

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

3D Structure with Domain Coloring

Domain Coloring

Taxonomy

Coding sequence (CDS)

Coding sequence (CDS)

Genome Context

Genome Context

Tertiary structure

Predicted Aligned Error (PAE)

Model Confidence