Protein

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Genbank accession
QBX28227.1 [GenBank]
Protein name
hyaluronate lyase
RBP type
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect2
Probability 0,96
Protein sequence
MAENIPLRVQFKRMSADEWARSDVILLESEIGFETDTGFARAGDGHNRFSDLGYISPLDYNLLTNKPNIDGLATKVETTQKLQQKADKETVYTKAESKQELDKKLNLKGGVMTGQLKFKPAATVAYSSSTGGAVNIDLSSTRGAGVVVYSDNDTSDGPLMSLRTGKETFNKSALFVDYKGTTNAVNIAMRQPSTPNFSSALNITSGNENGSAMQLRGSEKALGTLKITHENPNVKANYDENAAALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLSDDKFYVKSDGGFYAKETSQIDGNLKLKDPTANDHAATKAYVDKAISELKKLILKK
Physico‐chemical
properties
protein length:338 AA
molecular weight: 36525,66690 Da
isoelectric point:9,17548
aromaticity:0,06509
hydropathy:-0,53669

Domains

Domains [InterPro]
SSF69349
STR
7–336
SSF69349
IPR041352
ATT
9–45
IPR041352 IPR009860
QBX28227.1
1 338
Architecture
ATT
STR
ATT 7-45 | STR 46-336 |
Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout
N-terminal
Central
C-terminal
QBX28227.1
1 338
Domain Start End Length (AA) Confidence
N-terminal 1 112 112 0,9948
Central domain 113 311 200 0,1192
C-terminal 312 338 26 0,9894
Legend: N-terminal Central domain C-terminal
3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring
N-terminal
1-112
Central
113-311
C-terminal
312-338

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptococcus phage Javan446
[NCBI] 		2548172 Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host Streptococcus pyogenes Alab49
[NCBI] 		487215 Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus > Streptococcus pyogenes

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
QBX28227.1 [NCBI]
Genbank nucleotide accession
MK448941 [NCBI]
CDS location
range 34459 -> 35475
strand +
CDS
ATGGCCGAAAATATACCATTAAGAGTCCAATTTAAGCGCATGAGCGCTGATGAGTGGGCTCGTAGTGATGTCATCTTACTGGAGAGTGAAATAGGCTTTGAGACAGACACAGGTTTTGCCAGAGCAGGTGATGGCCACAATCGATTTAGTGACCTTGGATACATTAGCCCACTCGATTACAATCTACTGACTAACAAGCCAAATATCGATGGATTAGCGACAAAAGTCGAGACCACTCAGAAACTACAACAAAAAGCAGATAAAGAGACCGTCTATACAAAAGCTGAATCGAAGCAAGAGCTTGACAAGAAATTAAATCTCAAAGGTGGCGTTATGACAGGTCAACTAAAATTTAAGCCAGCCGCCACTGTTGCTTATTCCTCGTCAACGGGTGGAGCGGTCAATATTGACTTGTCGTCTACCAGAGGTGCTGGTGTTGTTGTCTATTCTGACAATGATACCAGTGATGGGCCGTTAATGAGCTTGCGGACGGGTAAAGAGACCTTCAATAAATCGGCGCTTTTTGTCGATTATAAGGGAACAACAAATGCCGTTAATATTGCGATGCGCCAGCCAAGCACACCTAATTTTTCCTCTGCGCTTAATATTACTAGCGGCAATGAAAATGGTAGTGCGATGCAGCTACGAGGGTCAGAAAAAGCATTGGGAACGCTAAAAATTACTCACGAAAACCCAAACGTTAAGGCAAATTACGATGAAAACGCTGCAGCGTTATCTATTGATATCGTTAAAAAACAGAAAGGCGGAAAAGGTACTGCTGCTCAAGGAATCTACATTAACTCAACATCAGGCACGACAGGGAAGTTGCTTAGGATTAGAAACCTTAGTGATGATAAGTTCTACGTCAAGTCTGACGGTGGTTTTTATGCCAAGGAAACTTCGCAGATTGATGGCAACCTGAAACTCAAGGACCCCACAGCGAATGATCATGCGGCAACCAAAGCTTATGTAGATAAAGCAATTTCTGAGTTAAAAAAACTCATACTAAAAAAATAG

Genome Context

Genome Context

Tertiary structure

PDB ID
0d474bff2863214ea4883d51f2ee601078f8635d1fa70737093ea9cddb82e664
ESMFold
Source ESMFold
Method ESMFold
Resolution 0,7722
Oligomeric State monomer
Download PDB
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50

Literature

Title Authors Date PMID Source
Prophages and satellite prophages are widespread among Streptococcus species and may play a role in pneumococcal pathogenesis Rezaei Javan,R., Ramos-Sevillano,E., Akter,A., Brown,J. and Brueggemann,A.B. 2018-12-20 — GenBank