Protein

View in Explore
Genbank accession
QUU29414.1 [GenBank]
Protein name
DpK2
RBP type
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect
Probability 0,91
TSP
Evidence RBPdetect2
Probability 0,95
TSP
Evidence DepoCatalog
Probability 1,00
Protein sequence
MALYREGKAAMAADGTVTGTGTKWQSSLSLIRPGATIMFLSSPIQMAVVNKVVSDTEIKAITTSGAVVASTDYAILLSDSLTVDGLAQDVAETLRHYQSQETVIADAVEFFKSFDFDSLQNLANQIKADSESAESSAAAAAASESKAKTSEDNAKSSENAAKNSEVAAETTRDQIQQIIDNAGDQSTLVVLAQPDGFDSIGRVSSFAALRNLKPKKSGQHVLLTSYYDGWAAENKMPTGGGEFISSIGTATDDGGYIAAGPGYYWTRVVNNNSFTAEDFGCKTTATPPPNFNVLPAELFDNTAMMQAAFNLAISKSFKLNLSTGTYYFESSDTLRITGPIHIEGRPGTVFYHNPSNKANPKTDAFMNISGCSAGRISSINCFSNSYLGKGINFDRSVGDNRKLVLEHVYVDTFRWGFYVGEPECINQIEFHSCRAQSNYFQGIFIESFKEGQEYGHSAPVHFFNTICNGNGPTSFALGATYKTTKNEYIKVMDSVNDVGCQAYFQGLSNVQYIGGQLSGHGSPRNTSLATITQCNSFIIYGTDLEDINGFTTDGTAITADNIDAIESNYLKDISGAAIVVSSCPGFKIDSPHIFKIKTLSTIKLMNNTYNYEIGGFTPDEALKYNVWDANGLATNRISGVIHPRLVNSRLGINSVAFDNMSNKLDVSSLIHNETSQIVGLTPSTGSNVPHTRKMWSNGAMYSSTDLNNGFRLNYLSNHNEPLTPMHLYNEFSVSEFGGSVTESNALDEIKYIFIQTTYANSGDGRFIIQALDASGSVLSSNWYSPQSFNSTFPISGFVRFDVPTGAKKIRYGFVNSANYTGSLRSHFMSGFAYNKRFFLKIYAVYNDLGRYGQFEPPYSVAIDRFRVGDNTTQMPSIPASSATDVAGVNEVINSLLASLKANGFMSS
Physico‐chemical
properties
protein length:907 AA
molecular weight: 98353,31640 Da
isoelectric point:5,37551
aromaticity:0,10695
hydropathy:-0,22205

Domains

Domains [InterPro]
IPR011050
288–481
IPR011050 G3DSA:6.10.140.1630
QUU29414.1
1 907
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Klebsiella phage RAD2
[NCBI] 		2831671 Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
QUU29414.1 [NCBI]
Genbank nucleotide accession
MW655991.1 [NCBI]
CDS location
range 4063 -> 6786
strand -
CDS
ATGGCACTATACAGAGAAGGTAAAGCGGCTATGGCCGCAGACGGAACCGTTACCGGCACTGGCACAAAATGGCAATCATCGCTTTCGCTGATTCGCCCCGGCGCGACGATTATGTTTTTGTCGTCACCGATTCAAATGGCCGTCGTAAACAAGGTGGTAAGTGACACGGAAATTAAAGCAATTACCACAAGCGGCGCTGTCGTAGCGTCTACTGACTACGCGATCCTGTTAAGCGACTCGCTGACCGTTGACGGCCTGGCGCAAGATGTTGCTGAAACCTTGCGCCACTATCAGTCGCAAGAAACAGTAATTGCTGATGCGGTAGAGTTCTTTAAGAGCTTTGATTTTGATTCACTGCAAAACCTTGCCAACCAAATTAAGGCAGACTCTGAATCTGCTGAATCAAGCGCTGCGGCTGCGGCTGCGTCTGAAAGTAAGGCAAAAACTTCAGAGGATAACGCAAAATCTTCTGAAAATGCGGCAAAAAATTCAGAGGTTGCAGCGGAGACTACAAGAGACCAAATTCAGCAGATCATTGACAACGCTGGAGATCAATCAACGCTGGTTGTTTTGGCGCAACCTGACGGATTTGACTCCATCGGTCGCGTCAGTTCATTTGCTGCTCTACGTAACTTGAAACCTAAAAAGTCTGGTCAGCATGTTCTGCTTACATCGTATTATGATGGTTGGGCGGCGGAAAATAAAATGCCAACAGGCGGTGGTGAGTTTATCAGTAGCATAGGAACGGCCACTGACGATGGTGGGTATATCGCTGCTGGCCCTGGGTACTATTGGACACGAGTGGTAAATAATAATTCATTTACAGCCGAGGATTTTGGTTGTAAAACTACTGCAACACCACCACCAAACTTTAACGTTTTACCTGCTGAACTTTTTGATAACACAGCAATGATGCAAGCCGCTTTCAATCTTGCAATTAGTAAATCTTTCAAATTAAATCTTAGCACAGGAACATACTATTTTGAAAGTTCAGATACATTAAGAATAACAGGGCCAATCCATATCGAAGGCCGTCCTGGGACTGTTTTTTATCACAACCCATCAAACAAGGCTAACCCAAAAACTGACGCCTTCATGAACATAAGCGGATGCTCGGCTGGAAGAATATCAAGCATAAATTGCTTTTCTAACTCATATTTAGGGAAGGGGATAAACTTTGATAGAAGCGTAGGAGACAATAGGAAATTAGTATTGGAGCACGTCTATGTAGACACGTTCAGATGGGGTTTCTATGTTGGCGAACCTGAATGTATCAATCAGATTGAATTTCATAGTTGCAGGGCGCAATCAAACTATTTTCAAGGTATATTCATTGAGTCTTTTAAAGAAGGGCAGGAATATGGACATAGCGCACCAGTACATTTTTTCAACACAATTTGCAACGGGAATGGGCCAACCAGTTTTGCTCTTGGTGCGACATATAAGACAACGAAAAATGAATATATCAAAGTAATGGATAGTGTTAATGATGTTGGTTGCCAGGCTTATTTCCAAGGATTAAGCAACGTTCAGTACATTGGCGGTCAGTTATCAGGACATGGGAGCCCGCGCAATACATCACTAGCAACTATAACACAATGTAATTCATTCATAATTTACGGAACTGATCTGGAGGACATTAATGGCTTCACAACTGACGGAACAGCAATAACGGCTGATAATATTGATGCTATTGAGTCAAATTACTTAAAGGATATTTCTGGCGCTGCAATAGTTGTGTCATCATGCCCTGGTTTTAAAATAGATAGCCCGCACATATTCAAAATCAAGACGCTATCTACAATAAAACTCATGAATAACACATATAATTATGAGATTGGTGGGTTCACTCCAGACGAGGCATTAAAATATAACGTATGGGATGCTAATGGATTGGCAACAAACAGAATATCTGGAGTAATACACCCAAGGCTTGTTAACTCGCGGCTTGGGATAAACAGTGTCGCATTTGATAACATGTCAAATAAACTTGATGTTTCATCTCTTATTCACAATGAAACATCACAAATTGTAGGGCTAACACCAAGCACTGGTTCAAATGTCCCTCACACAAGAAAAATGTGGAGCAATGGAGCAATGTATAGTTCAACTGACTTGAACAACGGTTTCAGGCTTAATTATCTAAGCAACCATAACGAACCGCTTACACCTATGCATCTATACAATGAGTTTTCTGTTTCTGAGTTTGGAGGATCAGTAACAGAATCAAACGCATTGGATGAAATTAAATACATATTCATTCAAACGACTTATGCAAACTCAGGTGATGGGAGGTTTATAATTCAGGCGCTTGATGCCAGTGGGTCTGTTTTGTCATCAAACTGGTATTCGCCTCAAAGCTTTAACTCAACGTTCCCGATAAGTGGATTCGTTAGGTTTGATGTTCCGACAGGTGCGAAGAAAATAAGATATGGATTTGTTAACAGTGCCAATTACACTGGCTCACTTAGATCGCACTTCATGTCTGGTTTTGCATATAATAAAAGGTTCTTCCTTAAAATATATGCTGTATACAATGACTTAGGTAGATATGGGCAATTTGAACCGCCATACTCGGTAGCTATTGATAGATTTAGAGTTGGTGATAATACAACGCAAATGCCATCAATACCTGCGAGTTCAGCTACAGATGTAGCTGGAGTGAACGAGGTTATAAACTCACTACTTGCATCTTTGAAAGCAAATGGATTTATGAGTAGCTAA

DepoCatalog

K-type Target
K2
Number of Rings

10

Structural Classification
Domain Ranges
N-terminal Domain
1-272
Central Domain
273-674
C-terminal Domain
675-907
Catalytic Information
Mechanism of Action: Hydrolase
Catalytic Site Location: Inter-subunit
Cleaved Bond: α-D-Glc-(1→3)-β-D-Glc
Experimentally Tested K-types
K1
K2
K3
K5
K6
K9
K11
K16
K17
K21
K22
K25
K26
K27
K28
K30
K38
K49
K52
K54
K60
K61
K64
K81
Phage Morphotype

Sipho-type

Tertiary structure

1 / 3
PDB ID
Source
Method
Resolution
Oligomeric State

Literature

Title Authors Date PMID Source
Mechanistic Insights into the Capsule-Targeting Depolymerase from a Klebsiella pneumoniae Bacteriophage Dunstan, Rhys A.; Bamert, Rebecca S.; Belousoff, Matthew J.; Short, Francesca L.; Barlow, Christopher K.; Pickard, Derek J.; Wilksch, Jonathan J.; Schittenhelm, Ralf B.; Strugnell, Richard A.; Dougan, Gordon 2021-01-01 — 10.1128/spectrum.01023-21