Phage RBP Database

Genbank accession

YP_009204272.1 [GenBank]

Protein name

tail protein with endopeptidase domain

RBP type

TF

Evidence GenBank

Probability 1,00

TSP

Evidence RBPdetect

Probability 0,80

Seq2Symm

C3 confidence 0,979

C3	0,979
C1	0,101
C2	0,001

Predicted homo-oligomer symmetry (Seq2Symm, per-class probabilities; C1 = monomer, C2 = dimer, C3 = trimer).

Protein sequence

MDYHDHLSVMDFNELICENLLDVDYGSFKEYYELNEARYITFTVYRTTHNSFVFDLLICENFIIYHGEKYTIKQTAPKVEGEKVFIEVTAYHIMYEFQNHSIESNKLDDDSSESSKTPEYTLEEYLRYGFANQKTSVKMTYKIIGDFKRKVPIDELGNKNGLEYCKEAVDLFGCIIYPNDTEIGFYSPETFYQRSEKVIRYQYNTDTVSATVSTLELRTAIKVFGKKYTAEEKKNYNPIRTTDIKYSNGFIKEGTYRTETIGSKATINFDCKYGNETVRFTIKKGSQGGIYKLILDGKQIKQISCFAKSVQSETIDLIKNIDKGKHVLEMIFLGEDPKNRIDISSNKKAKPCMYVGTEKSTVLNLIADNSGRNQYKAIVDYVADSAKQFGIRYANTQTNEDIETQDKLLEFAKKQINDTPKTELDVNYIGYEKIEPRDSVFFVHELMGYNTELKVVKLDRSHPFVNAIDEVSFSNEIKDMVQIQQALNRRVIAQDNRYNYQANRINHLYTSTLNSPFETMDIGSVLI

Physico‐chemical properties

protein length:	527 AA
molecular weight:	61003,13650 Da
isoelectric point:	5,66255
aromaticity:	0,11765
hydropathy:	-0,54554

Domain architecture

YP_009204272.1

1 527 aa

ATT 4–90 · STR 91–192 · ENZ 193–486 ·

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

InterPro domains

G3DSA:6.20.110.10
ATT

G3DSA:6.20.110.10 G3DSA:3.55.50.40

IPR044051
ENZ

IPR044051 IPR010572

YP_009204272.1

1527 aa

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

Novel HMM domains (de novo, PhaRBP-HMM)

Experimental de novo families on regions without InterPro annotation. Separate from the InterPro architecture above.

DC_1309
STR

DC_1309 DC_0297

YP_009204272.1

1527 aa

InterPro domain annotations

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
G3DSA:6.20.110.10	ATT	G3DSA:6.20.110.10	4	90	Merged direct domain	G3DSA:6.20.110.10	N-terminal	Low	Positional only	47 proteins / 47 hits
IPR044051	ENZ	DC_0346	18	92	InterPro cluster	Prophage endopeptidase tail, N-terminal	N-terminal	High	Text match	59 proteins / 59 hits
G3DSA:3.55.50.40	STR	G3DSA:3.55.50.40	92	192	Merged direct domain	G3DSA:3.55.50.40	Central	Low	Positional only	63 proteins / 63 hits
IPR010572	ENZ	DC_0675	112	486	InterPro cluster	Tail spike domain	Central	High	Text match	419 proteins / 419 hits

Proteins with similar domain architecture

Segmented into three structural domains: N-terminal, central, and C-terminal.

Domain layout

YP_009204272.1

1 527 aa

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	231	231	0,7872
Central domain	232	435	205	0,4969
C-terminal	436	527	91	0,0034

Note: Constraints were applied during segmentation.
Fixed 32 C-terminal predictions appearing before Central domain

N-terminal Central domain C-terminal

View these domains on the 3D structure via the Color by → Tail spike option in the Tertiary structure section below.

Phage

Staphylococcus phage vB_SauS_phi2 [NCBI] · taxon 1674930

Uroviricota Caudoviricetes Triavirus Triavirus tv2

Host

Staphylococcus aureus [NCBI] · taxon 1280

Bacillota Bacilli Caryophanales Staphylococcaceae Staphylococcus Staphylococcus aureus

Genbank protein accession

YP_009204272.1 [NCBI]

Genbank nucleotide accession

NC_028862 [NCBI]

CDS location

range 15571 -> 17154
strand +

CDS

ATGGATTATCATGATCATTTATCAGTAATGGATTTTAATGAATTGATTTGTGAAAATTTACTAGATGTAGATTACGGTTCTTTTAAAGAATATTATGAACTGAATGAAGCTAGGTACATCACTTTTACAGTTTATAGAACTACTCATAATAGTTTTGTTTTCGATTTACTAATTTGTGAAAATTTCATTATTTATCATGGTGAAAAATACACAATCAAGCAGACAGCACCGAAGGTTGAGGGAGAAAAAGTTTTTATTGAAGTTACGGCATATCATATTATGTATGAATTTCAAAATCACTCTATTGAATCAAATAAGCTTGATGACGACAGTAGCGAATCTTCAAAAACGCCAGAATACACGTTAGAAGAGTATTTGAGATACGGATTTGCAAATCAAAAAACTTCGGTCAAAATGACCTATAAAATAATTGGAGATTTTAAGCGAAAAGTACCGATTGACGAATTAGGTAACAAAAACGGCTTAGAATACTGTAAAGAAGCGGTAGACCTGTTTGGCTGTATAATTTACCCAAATGATACAGAGATTGGTTTTTATTCTCCTGAAACATTTTATCAAAGAAGCGAGAAAGTGATTCGATATCAATATAATACTGATACTGTATCTGCAACTGTCAGTACATTGGAATTAAGAACAGCTATAAAAGTTTTTGGAAAAAAGTATACAGCTGAGGAAAAGAAAAATTATAATCCTATTAGAACAACTGACATTAAATATTCAAATGGTTTTATAAAAGAAGGTACTTATCGTACCGAAACAATTGGGTCTAAAGCTACTATTAACTTTGATTGCAAGTATGGTAATGAAACAGTTAGATTTACAATAAAAAAGGGCTCTCAAGGTGGAATATATAAGTTGATTTTAGACGGCAAGCAAATTAAGCAAATTTCTTGTTTTGCTAAGTCGGTTCAGTCTGAAACAATAGATTTAATAAAAAATATTGATAAAGGCAAGCACGTTTTAGAAATGATATTTTTAGGAGAAGACCCCAAAAATAGAATTGATATATCTTCAAATAAAAAAGCTAAGCCTTGTATGTATGTTGGAACTGAAAAATCAACAGTCTTAAATTTAATTGCTGATAATTCAGGTCGCAATCAATACAAAGCAATTGTCGACTACGTCGCAGATAGTGCAAAGCAGTTTGGGATTCGATATGCTAATACGCAAACAAATGAAGATATCGAAACACAGGATAAGCTGTTAGAATTTGCAAAAAAGCAAATAAATGATACTCCTAAGACTGAATTAGATGTTAATTATATAGGTTATGAAAAAATAGAACCAAGAGATAGCGTATTTTTTGTTCATGAATTAATGGGATATAACACTGAATTAAAGGTTGTTAAACTTGATAGGTCACATCCATTTGTAAACGCAATAGATGAAGTGTCTTTCAGCAATGAAATAAAAGATATGGTACAAATTCAACAAGCACTTAACAGACGAGTTATTGCACAAGATAATAGATATAACTATCAAGCAAATCGTATAAATCATTTATACACTAGTACTTTGAATTCTCCTTTCGAGACAATGGATATAGGGAGTGTATTAATATAA

Title	Authors	Date	PMID	Source
Efficacy of two Staphylococcus aureus phage cocktails in cheese production	El Haddad,L., Roy,J.-P., Khalil,G.E., St-Gelais,D., Champagne,C.P., Labrie,S. and Moineau,S.	2016-01	—	GenBank

Protein

Domains

Tail Spike Domain Segmentation

Taxonomy

Coding sequence (CDS)

Genome Context

Tertiary structure

Predicted Aligned Error (PAE)

Literature