Phage RBP Database

UniProt accession

A0A9Y2E178 [UniProt]

Protein name

Probable tail spike protein

RBP type

TSP

Evidence DepoScope

Probability 1,00

TSP

Evidence RBPdetect

Probability 0,90

TSP

Evidence RBPdetect2

Probability 0,94

Seq2Symm

C3 confidence 0,999

C3	0,999
C1	0,003
D3	0,001

Predicted homo-oligomer symmetry (Seq2Symm, per-class probabilities; C1 = monomer, C2 = dimer, C3 = trimer).

Protein sequence

MDQDIKTVIQYPVGTTEFDIPFDYLSRKFVRVSLVANDNRRLLSNITEYRYVSKTRVKILVDTAGFDRVEIRRFTSASERVVDFSDGSVLRANDLNVSQLQSAHIAEEARDSALMAMPEDDAGNLDARNRKIVRLAPGEIGSDAVNKDQLDTAVGDAGGILSDVKKVQQETYDYIEKFADDTALVRGVSWVYNQGSANGGETSILIDKPTRVLAVPYIEVNGLRQEVGYHFSFDIATQRITLVKPLVAGDFLVALTTESSVPVEDLLANPTGASSIGTSDGRNVQVVLDGLTADLQTARSAVSPKEFGGVPNTDATAAIKLAIAAALVRKAPLDLRSGPWTITETIDLTDIKTVIADATGVLRVDPTTFTSKFSNKYAVTFGNPDVTFGQGRSSHVQVIGTLVVSGLNRAGALNGVYFKGSWFASNVVRVSGLNGSAIVLEAVWDSVFQSLSAELCGNEANYQIDVRGGGDTSNCIHIGRIQSERAYHKCLRISAIRSVFNTIHAERTAVLTTDDGSTNADGTKYTTLMFSLGNSVVNQLIHDAISGNAPDGRPTVGMASSRIDADYCVINAAGLTGSGLSSNSGRNTTWNGMVVRKWTFSGTATGHTIVSPRIIESLVPNNSITVKGGTAGQVSFGYNAKDVQIDSMAIDDLSFPNTIRGNINFTSCTFPETLTIGSTRAPEGYTAQSTLGETNTPVTFTDCVHLGTLAGAFQSRCVWKGGYIANISLVSRAAVELYNVSTKSFSATGDRAYITRQVRATNVGSWGVPTHVAYPIGTITERLGTDELNVGTGFRNADGTTTGFIKIY

Physico‐chemical properties

protein length:	808 AA
molecular weight:	86495,90560 Da
isoelectric point:	5,63464
aromaticity:	0,07426
hydropathy:	-0,08577

Domain architecture

A0A9Y2E178

1 808 aa

ATT 3–127 ·

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

InterPro domains

IPR005604
ATT

IPR005604

A0A9Y2E178

1808 aa

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

Novel HMM domains (de novo, PhaRBP-HMM)

Experimental de novo families on regions without InterPro annotation. Separate from the InterPro architecture above.

DC_0225
ATT

DC_0225 DC_1269

A0A9Y2E178

1808 aa

InterPro domain annotations

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
IPR005604	ATT	DC_0240	3	127	InterPro cluster	Bacteriophage T7 tail fibre protein-like, N-terminal domain	Central	Medium	Text match	1326 proteins / 1328 hits

Proteins with similar domain architecture

Segmented into three structural domains: N-terminal, central, and C-terminal.

Domain layout

A0A9Y2E178

1 808 aa

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	313	313	0,9939
Central domain	314	763	451	0,9924
C-terminal	764	808	44	0,9342

N-terminal Central domain C-terminal

View these domains on the 3D structure via the Color by → Tail spike option in the Tertiary structure section below.

Phage

Klebsiella phage vB_KpnP_2146-HW [NCBI] · taxon 3038211

Uroviricota Caudoviricetes Autographivirales Autotranscriptaviridae Przondovirus Przondovirus 2146HW

Host

Klebsiella sp. [NCBI] · taxon 576

Pseudomonadota Gammaproteobacteria Enterobacterales Enterobacteriaceae Klebsiella Klebsiella sp.

No CDS data available.

	Description	Category	Evidence (source)
GO:0098015	virus tail	Cellular Component	IEA:UniProtKB-KW (UniProt)
GO:0098671	adhesion receptor-mediated virion attachment to host cell	Biological Process	IEA:UniProtKB-KW (UniProt)
GO:0098994	symbiont entry into host cell via disruption of host cell envelope	Biological Process	IEA:UniProtKB-KW (UniProt)
GO:0098996	symbiont entry into host cell via disruption of host cell glycocalyx	Biological Process	IEA:UniProtKB-KW (UniProt)

Protein

Domains

Tail Spike Domain Segmentation

Taxonomy

Coding sequence (CDS)

Genome Context

Gene Ontology

Tertiary structure

Predicted Aligned Error (PAE)