Protein

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UniProt accession

A0AAE7VPM2 [UniProt]

Protein name

BIG2 domain-containing protein

RBP type

TSP

Evidence DepoScope

Probability 1,00

Protein sequence

MSDYGNVILKAFPGCLSDTSDYNIDGACVVGGQGEGSGGEHVFSGCAVWVESVDPGGHKIVRQNLISTQNVPYGIAMTHHYAPHESADGYAMYNVGDVINVVTHGRVWVYGNNTDITPTFGQRVRIQTNGTVGTSGGTLVNWRFTGGKVIIKPNVAIFEVQLVQGINAFLVVHGGDMVINPNSIEAGATVQARLIAITPAAPDRTGKFSSEDEGVATVDQDTGLITGVAAGTTNIVWTANDSGKYTITRPITVTEAPPAP

Physico‐chemical properties

protein length:	260 AA
molecular weight:	27259,17220 Da
isoelectric point:	5,09876
aromaticity:	0,07308
hydropathy:	-0,01154

Domains

Domains [InterPro]

IPR054438
STR
4–161

IPR054438 DC_1711

IPR003343
STR
173–249

IPR003343

G3DSA:2.60.40.1080
STR
177–256

G3DSA:2.60.40.1080

IPR003343
STR
182–246

IPR003343

IPR008964
RBD
185–253

IPR008964

A0AAE7VPM2

1 260

Architecture

STR

STR 4-161 | STR 168-260

Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Domains [InterPro]

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
IPR054438	STR	DC_0132	4	161	InterPro cluster	Structural cement protein E217 gp24/Pam3 gp6	Central	Low	Positional only	30 proteins / 30 hits
DC_1711	RBD	DC_1711	168	260	Novel HMM	DC_1711	C-terminal	Low	Positional only	141 proteins / 141 hits
IPR003343	STR	DC_0008	173	249	InterPro cluster	Bacterial Ig-like domain, group 2	C-terminal	Medium	Text match	304 proteins / 473 hits
G3DSA:2.60.40.1080	STR	G3DSA:2.60.40.1080	177	256	Merged direct domain	G3DSA:2.60.40.1080	Central	Low	Positional only	18 proteins / 18 hits
IPR003343	STR	DC_0008	182	246	InterPro cluster	Bacterial Ig-like domain, group 2	C-terminal	Medium	Text match	304 proteins / 473 hits
IPR008964	RBD	IPR008964	185	253	Merged direct domain	Invasin/intimin cell-adhesion fragments	C-terminal	Low	Positional only	2 proteins / 2 hits

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout

N-terminal

Central

C-terminal

A0AAE7VPM2

1 260

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	254	254	0,3321
Central domain	255	254	1	0,0227
C-terminal	255	260	5	0,9851

Note: Constraints were applied during segmentation.
Sequence started with non-N-terminal domain|C-terminal too short, adjusted boundary|CONSTRAINT VIOLATION: Final C-terminal (5 AA) is still below minimum (10 AA). Sequence may be too short.

Legend: N-terminal Central domain C-terminal

3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring

N-terminal
1-254

Central
255-254

C-terminal
255-260

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Escherichia phage BrunoManser [NCBI]	2851976	Uroviricota > Caudoviricetes > Drexlerviridae > Sertoctavirus > Sertoctavirus brunomanser
Host	Escherichia coli K-12 [NCBI]	83333	Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Escherichia

Coding sequence (CDS)

No CDS data available.

Genome Context

Tertiary structure

PDB ID

528d41c803d89ee9e9d1e249e28a36d7a9e069c0c565ac937063e40ccda41f20

ESMFold

Source ESMFold

Method ESMFold

Resolution 0,8299

Oligomeric State monomer

Download PDB

Model Confidence

Very high
pLDDT > 90

High
90 > pLDDT > 70

Low
70 > pLDDT > 50

Very low
pLDDT < 50

Protein

Domains

Domains [InterPro]

Domains [InterPro]

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

3D Structure with Domain Coloring

Domain Coloring

Taxonomy

Coding sequence (CDS)

Coding sequence (CDS)

Genome Context

Genome Context

Tertiary structure

Predicted Aligned Error (PAE)

Model Confidence