Phage RBP Database

UniProt accession

A0AAE7VPM2 [UniProt]

Protein name

BIG2 domain-containing protein

RBP type

TSP

Evidence DepoScope

Probability 1,00

Seq2Symm

I confidence 0,234

I	0,234
C3	0,019
C2	0,003

Predicted homo-oligomer symmetry (Seq2Symm, per-class probabilities; C1 = monomer, C2 = dimer, C3 = trimer).

Protein sequence

MSDYGNVILKAFPGCLSDTSDYNIDGACVVGGQGEGSGGEHVFSGCAVWVESVDPGGHKIVRQNLISTQNVPYGIAMTHHYAPHESADGYAMYNVGDVINVVTHGRVWVYGNNTDITPTFGQRVRIQTNGTVGTSGGTLVNWRFTGGKVIIKPNVAIFEVQLVQGINAFLVVHGGDMVINPNSIEAGATVQARLIAITPAAPDRTGKFSSEDEGVATVDQDTGLITGVAAGTTNIVWTANDSGKYTITRPITVTEAPPAP

Physico‐chemical properties

protein length:	260 AA
molecular weight:	27259,17220 Da
isoelectric point:	5,09876
aromaticity:	0,07308
hydropathy:	-0,01154

Domain architecture

A0AAE7VPM2

1 260 aa

STR 4–161 · STR 173–256 ·

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

InterPro domains

IPR054438
STR

IPR054438 IPR003343

G3DSA:2.60.40.1080
STR

G3DSA:2.60.40.1080

IPR003343
STR

IPR003343

IPR008964
RBD

IPR008964

A0AAE7VPM2

1260 aa

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

Novel HMM domains (de novo, PhaRBP-HMM)

Experimental de novo families on regions without InterPro annotation. Separate from the InterPro architecture above.

DC_1711
RBD

DC_1711

A0AAE7VPM2

1260 aa

InterPro domain annotations

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
IPR054438	STR	DC_0132	4	161	InterPro cluster	Structural cement protein E217 gp24/Pam3 gp6	Central	Low	Positional only	30 proteins / 30 hits
IPR003343	STR	DC_0008	173	249	InterPro cluster	Bacterial Ig-like domain, group 2	C-terminal	Medium	Text match	304 proteins / 473 hits
G3DSA:2.60.40.1080	STR	G3DSA:2.60.40.1080	177	256	Merged direct domain	G3DSA:2.60.40.1080	Central	Low	Positional only	18 proteins / 18 hits
IPR003343	STR	DC_0008	182	246	InterPro cluster	Bacterial Ig-like domain, group 2	C-terminal	Medium	Text match	304 proteins / 473 hits
IPR008964	RBD	IPR008964	185	253	Merged direct domain	Invasin/intimin cell-adhesion fragments	C-terminal	Low	Positional only	2 proteins / 2 hits

Proteins with similar domain architecture

Segmented into three structural domains: N-terminal, central, and C-terminal.

Domain layout

A0AAE7VPM2

1 260 aa

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	254	254	0,3321
Central domain	255	254	1	0,0227
C-terminal	255	260	5	0,9851

Note: Constraints were applied during segmentation.
Sequence started with non-N-terminal domain|C-terminal too short, adjusted boundary|CONSTRAINT VIOLATION: Final C-terminal (5 AA) is still below minimum (10 AA). Sequence may be too short.

N-terminal Central domain C-terminal

View these domains on the 3D structure via the Color by → Tail spike option in the Tertiary structure section below.

Phage

Escherichia phage BrunoManser [NCBI] · taxon 2851976

Uroviricota Caudoviricetes Drexlerviridae Sertoctavirus Sertoctavirus brunomanser

Host

Escherichia coli K-12 [NCBI] · taxon 83333

Pseudomonadota Gammaproteobacteria Enterobacterales Enterobacteriaceae Escherichia Escherichia coli

No CDS data available.

Protein

Domains

Tail Spike Domain Segmentation

Taxonomy

Coding sequence (CDS)

Genome Context

Tertiary structure

Predicted Aligned Error (PAE)