Protein
View in Explore- UniProt accession
- P23207 [UniProt]
- Protein name
- Receptor-binding protein pb5
- RBP type
-
TSPTSP
- Protein sequence
-
MSFFAGKLNNKSILSLRRGSGGDTNQHINPDSQTIFHSDMSHVIITETHSTGLRLDQGAGDYYWSEMPSRVTQLHNNDPNRVVLTEIEFSDGSRHMLSGMSMGVGAKAYGIINPQIMSQGGLKTQITASADLSLDVGYFNTGTSGTIPQKLRDGTGCQHMFGAFSGRRGFASSAMYLGGAALYKSAWSGSGYVVADAGTLTIPSDYVRHPGARNFGFNAIYVRGRSCNRVLYGMEGPNYTTGGAVQGASSSGALNFTYNPSNPESPKYSVGFARADPTNYAYWESMGDPNDSANGPIGIYSEHLGIYPSKITWYVTNLVYNGSGYNIDGGLFNGNDIKLSPREFIIKGVNVNNTSWKFINFIEKNFNVGNRADFRDVGCNLSKDSPSTGISGIATFGLPTTESNNAPSIKGGNVGGLHANVVSIYNFLPSASWYVSSNPPKIGNNYGDVWSENLLPLRLLGGSGSTILSGNIVFQGNGSVHVGTVGLDLNSSRNGAIVCTMEFIDDTWLSAGGIGCFNPTEMLSQGAEYGDSRFRIGGNTINKKLHQILSLPAGEYVPFFTIKGTVVNACKLQAAAYNPTPYWVSGLPGSVGQTGYYTLTYYMRNDGNNNISIWLDSSMSNIIGMKACLPNIKLIIQRLT
- Physico‐chemical
properties -
protein length: 640 AA molecular weight: 68725,13840 Da isoelectric point: 8,01937 aromaticity: 0,10469 hydropathy: -0,22297
Domains
Domains [InterPro]
No domain annotations available.
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Pfam
SMART
CDD
TIGRFAM
HAMAP
SUPFAM
PRINTS
Gene3D
PANTHER
Other
Taxonomy
| Name | Taxonomy ID | Lineage | |
|---|---|---|---|
| Phage |
Escherichia phage T5 [NCBI] |
2695836 | Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes |
| Host | No host information | ||
Coding sequence (CDS)
Gene Ontology
| Description | Category | Evidence (source) | |
|---|---|---|---|
| GO:0098015 | virus tail | Cellular Component | IEA:UniProtKB-KW (UniProt) |
| GO:0098670 | entry receptor-mediated virion attachment to host cell | Biological Process | IEA:UniProtKB-KW (UniProt) |
| GO:0046813 | receptor-mediated virion attachment to host cell | Biological Process | IDA:UniProtKB (UniProt) |
| GO:0046718 | symbiont entry into host cell | Biological Process | IEA:UniProtKB-KW (UniProt) |
Tertiary structure
1 / 3
PDB ID
Literature
| Title | Authors | Date | PMID | Source |
|---|---|---|---|---|
| Insights into bacteriophage T5 structure from analysis of its morphogenesis genes and protein components. | Zivanovic Y, Confalonieri F, Ponchon L, Lurz R, Chami M, Flayhan A, Renouard M, Huet A, Decottignies P, Davidson AR, Breyton C, Boulanger P | 2014-01 | 24198424 | PubMed |
| Assessing the conformational changes of pb5, the receptor-binding protein of phage T5, upon binding to its Escherichia coli receptor FhuA. | Breyton C, Flayhan A, Gabel F, Lethier M, Durand G, Boulanger P, Chami M, Ebel C | 2013-10-18 | 24014030 | PubMed |
| Structural basis for host recognition and superinfection exclusion by bacteriophage T5. | van den Berg B, Silale A, Baslé A, Brandner AF, Mader SL, Khalid S | 2022-10-18 | 36215462 | PubMed |
| Characterization of a high-affinity complex between the bacterial outer membrane protein FhuA and the phage T5 protein pb5. | Plançon L, Janmot C, le Maire M, Desmadril M, Bonhivers M, Letellier L, Boulanger P | 2002-04-26 | 12051859 | PubMed |
| Cloning, sequencing, and recombinational analysis with bacteriophage BF23 of the bacteriophage T5 oad gene encoding the receptor-binding protein. | Krauel V, Heller KJ | 1991-02 | 1825083 | PubMed |
| New insights into pb5, the receptor binding protein of bacteriophage T5, and its interaction with its Escherichia coli receptor FhuA. | Flayhan A, Wien F, Paternostre M, Boulanger P, Breyton C | 2012-09 | 22659573 | PubMed |
| Complete genome sequence of bacteriophage T5. | Wang J, Jiang Y, Vincent M, Sun Y, Yu H, Wang J, Bao Q, Kong H, Hu S | 2005-02-05 | 15661140 | PubMed |
| Lytic conversion of Escherichia coli by bacteriophage T5: blocking of the FhuA receptor protein by a lipoprotein expressed early during infection. | Decker K, Krauel V, Meesmann A, Heller KJ | 1994-04 | 8057856 | PubMed |
| Deciphering Bacteriophage T5 Host Recognition Mechanism and Infection Trigger. | Degroux S, Effantin G, Linares R, Schoehn G, Breyton C | 2023-03-30 | 36779755 | PubMed |
| Structural basis of bacteriophage T5 infection trigger and E. coli cell wall perforation. | Linares R, Arnaud CA, Effantin G, Darnault C, Epalle NH, Boeri Erba E, Schoehn G, Breyton C | 2023-03-24 | 36961893 | PubMed |
| Deciphering Bacteriophage T5 Host Recognition Mechanism and Infection Trigger | Séraphine Degroux, Grégory Effantin, Romain Linares, Guy Schoehn, Cécile Breyton | 2023-03-30 | 10.1128/jvi.01584-22 | DOI |
| Insights into Bacteriophage T5 Structure from Analysis of Its Morphogenesis Genes and Protein Components | Yvan Zivanovic, Fabrice Confalonieri, Luc Ponchon, Rudi Lurz, Mohamed Chami, Ali Flayhan, Madalena Renouard, Alexis Huet, Paulette Decottignies, Alan R. Davidson, Cécile Breyton, Pascale Boulanger | 2014-01-15 | 10.1128/jvi.02262-13 | DOI |
| Structural basis of bacteriophage T5 infection trigger and <i>E. coli</i> cell wall perforation | Romain Linares, Charles-Adrien Arnaud, Grégory Effantin, Claudine Darnault, Nathan Hugo Epalle, Elisabetta Boeri Erba, Guy Schoehn, Cécile Breyton | 2023-03-24 | 10.1126/sciadv.ade9674 | DOI |
| Characterization of a High-affinity Complex Between the Bacterial Outer Membrane Protein FhuA and the Phage T5 Protein pb5 | L Plançon, C Janmot, M le Maire, M Desmadril, M Bonhivers, L Letellier, P Boulanger | 2002-04 | 10.1016/s0022-2836(02)00089-x | DOI |
| Lytic conversion of <i>Escherichia coli</i> by bacteriophage T5: blocking of the FhuA receptor protein by a lipoprotein expressed early during infection | Katja Decker, Verena Krauel, Anke Meesmann, Knut J. Heller | 1994-04 | 10.1111/j.1365-2958.1994.tb01020.x | DOI |
| Structural basis for host recognition and superinfection exclusion by bacteriophage T5 | Bert van den Berg, Augustinas Silale, Arnaud Baslé, Astrid F. Brandner, Sophie L. Mader, Syma Khalid | 2022-10-10 | 10.1073/pnas.2211672119 | DOI |
| Complete genome sequence of bacteriophage T5 | Jianbin Wang, Yan Jiang, Myriam Vincent, Yongqiao Sun, Hong Yu, Jing Wang, Qiyu Bao, Huimin Kong, Songnian Hu | 2005-02 | 10.1016/j.virol.2004.10.049 | DOI |
| Assessing the Conformational Changes of pb5, the Receptor-binding Protein of Phage T5, upon Binding to Its Escherichia coli Receptor FhuA | Cécile Breyton, Ali Flayhan, Frank Gabel, Mathilde Lethier, Grégory Durand, Pascale Boulanger, Mohamed Chami, Christine Ebel | 2013-10 | 10.1074/jbc.m113.501536 | DOI |
| Cloning, sequencing, and recombinational analysis with bacteriophage BF23 of the bacteriophage T5 oad gene encoding the receptor-binding protein | V Krauel, K J Heller | 1991-02 | 10.1128/jb.173.3.1287-1297.1991 | DOI |
| New insights into pb5, the receptor binding protein of bacteriophage T5, and its interaction with its Escherichia coli receptor FhuA | Ali Flayhan, Frank Wien, Maïté Paternostre, Pascale Boulanger, Cécile Breyton | 2012-09 | 10.1016/j.biochi.2012.05.021 | DOI |