Protein

Validated by sequence identity RBP function shown
View in Explore
Genbank accession
BAW85696.1 [GenBank]
Protein name
S2-2 (tail fiber protein)
RBP type
TSP
Evidence DepoCatalog
Probability 1,00
TSP
Evidence DepoScope
Probability 1,00
TF
Evidence GenBank
Probability 1,00
TF
Evidence Phold
Probability 1,00
TSP
Evidence RBPdetect
Probability 0,91
TSP
Evidence RBPdetect2
Probability 0,99
Seq2Symm
C3 confidence 1,000
C3 1,000
C1 0,020
C2 0,000
Predicted homo-oligomer symmetry (Seq2Symm, per-class probabilities; C1 = monomer, C2 = dimer, C3 = trimer).
Protein sequence
MGNFIQPKGSTSTEIAREILSKTYSINYSEIDFIKQNLSVNGLKLLIDPNTQYIWGTISSLETGTISSWSIDSTGEIMTVLTTNGTLTLRKISVSTSTTTANSIYNFMTSDDIYNIKNVVGIEINVDYALQKAINSGLMSIYYPPSKGIYVHSNVCTLPSGFNMYGQSRKPYTVSNDASFNNCGTVIRLASGSPGIFVLSGRHTFDNIVFDGRNNTVGSMNATSQVSGCRFEKCGFYRWGIGLGRTSGYVATVYARGCNFSGNNTAMQDWIDSRAVDCTINAQVSRGIAMRTGANNNAWVGCRVEWNGTDGFYFYQSVGNVITGELIDRNGYAGITVADGASVSVTTCSIQRNGRISSNTNNGANILINDSGIILLNGNRFTSGVDDGGTGVLTPDYDIICAGGTGKILIASGNSFSGGNLGYMKEVTIANKVITGNYGLPDIVNTGTYQKSSGLVKMGNTSTGTLPPAASNGTLTLSLSRPAMTQYMIPQKIVLEISARDTIGGRAEYFTVPLLCSWESTVPVINMISSKLDTYPDNVWGPSTNTPTGVQVSVSTTSDGSTITINLVSMDTRNRQIQAYIRGA
Physico‐chemical
properties
protein length:584 AA
molecular weight: 62475,47190 Da
isoelectric point:7,92789
aromaticity:0,08390
hydropathy:-0,09229

Domains

View on InterPro
Domain architecture
BAW85696.1
1 584 aa
ATT 2–100 · STR 127–475 ·
ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped
Proteins with similar domain architecture

Tail Spike Domain Segmentation

Segmented into three structural domains: N-terminal, central, and C-terminal.

Domain layout
BAW85696.1
1 584 aa
Domain Start End Length (AA) Confidence
N-terminal 1 126 126 0,9616
Central domain 127 451 326 0,9907
C-terminal 452 584 132 0,9698
N-terminal Central domain C-terminal

View these domains on the 3D structure via the Color by → Tail spike option in the Tertiary structure section below.

Taxonomy

Phage
Klebsiella phage K64-1 [NCBI] · taxon 1439894
Uroviricota Caudoviricetes Alcyoneusvirus Alcyoneusvirus K641
Host
Klebsiella pneumoniae [NCBI] · taxon 573
Pseudomonadota Gammaproteobacteria Enterobacterales Enterobacteriaceae Klebsiella Klebsiella pneumoniae

Coding sequence (CDS)

Genbank protein accession
BAW85696.1 [NCBI]
Genbank nucleotide accession
LC121102.1 [NCBI]
CDS location
range 1 -> 1755
strand +
CDS
ATGGGAAATTTTATACAACCTAAAGGTTCAACTTCTACTGAAATCGCTAGAGAAATTTTATCTAAAACTTATTCAATAAATTATTCTGAAATAGATTTTATAAAACAAAATCTTTCAGTTAATGGTTTAAAACTTCTTATTGATCCAAATACTCAATATATATGGGGAACTATTTCAAGTTTAGAAACTGGAACAATTTCATCATGGAGTATAGATAGTACTGGCGAAATTATGACTGTATTAACTACTAATGGCACTTTAACATTAAGAAAAATTTCTGTTTCTACTTCAACAACAACCGCAAATTCTATATATAATTTTATGACATCTGATGATATTTACAACATAAAAAATGTAGTTGGGATTGAAATTAATGTTGATTATGCTTTACAAAAAGCAATAAATTCTGGATTAATGTCAATTTATTATCCACCATCTAAAGGTATATATGTACATAGTAATGTATGTACATTACCATCAGGATTCAATATGTATGGTCAAAGTAGAAAACCATACACTGTTTCGAATGATGCATCATTTAATAATTGCGGTACTGTTATTAGATTAGCATCTGGTTCGCCTGGTATTTTTGTTCTTTCAGGGAGACATACTTTCGACAATATTGTATTTGATGGTAGAAACAACACAGTGGGTTCTATGAATGCTACATCACAAGTTTCTGGGTGTAGATTCGAAAAATGTGGATTTTATAGATGGGGTATTGGTTTAGGAAGAACTAGTGGGTATGTAGCAACCGTTTATGCTCGTGGTTGTAATTTTAGTGGTAATAATACAGCAATGCAAGACTGGATTGACTCTCGTGCAGTCGATTGTACAATAAATGCACAAGTCTCTCGTGGCATTGCGATGCGAACAGGAGCTAATAATAATGCATGGGTTGGGTGCCGAGTAGAATGGAATGGAACCGATGGTTTTTATTTTTATCAATCAGTAGGTAATGTAATTACTGGGGAATTGATTGACCGTAACGGATATGCAGGAATTACTGTTGCCGATGGTGCAAGTGTATCAGTTACAACCTGCTCAATACAACGAAACGGAAGAATATCCTCTAATACAAATAATGGGGCTAATATATTAATTAATGATTCTGGGATAATTTTATTAAATGGTAATAGATTTACTTCTGGTGTAGATGACGGTGGTACTGGTGTATTAACACCAGATTATGATATTATATGTGCTGGTGGTACTGGAAAAATCCTTATTGCTTCAGGAAATTCGTTTTCGGGTGGAAACTTAGGCTATATGAAAGAAGTAACTATAGCTAATAAAGTAATAACCGGAAACTATGGTTTACCTGATATAGTTAATACAGGGACATATCAAAAATCATCTGGTTTGGTTAAAATGGGGAATACATCTACTGGAACATTACCGCCAGCAGCATCAAATGGAACATTAACATTATCATTAAGCAGACCAGCAATGACACAATATATGATTCCACAAAAAATAGTTCTTGAGATATCAGCAAGAGATACTATAGGTGGAAGAGCTGAATATTTTACAGTACCTCTATTGTGTTCATGGGAAAGCACCGTACCCGTAATTAATATGATATCATCGAAATTAGATACATATCCAGACAATGTATGGGGTCCAAGTACAAATACACCTACTGGGGTTCAAGTATCTGTTAGTACAACATCTGATGGTTCTACTATTACTATCAACTTAGTATCTATGGATACAAGAAATAGACAAATACAAGCTTATATTAGAGGTGCATAA

Genome Context

Tertiary structure

BAW85696.1
1 / 2
Structure ID
Source
Method
Resolution
Oligomeric state

Experimental validation

Validated by sequence identity

The evidence was produced on a different entry with an identical sequence. Strong, but the experiment was not done on this protein.

Tier Source Assay Claim Reference
Validated by sequence identity GO
GO:0098996
 GO:IDA RBP symbiont entry into host cell via disruption of host cell glycocalyx ECO:0000314
Validated by sequence identity UniProt
A0A0A8J9V7
 ECO:0000269:FUNCTION:28077636 RBP Functions as a receptor binding protein (RBP) and probably mediates the attachment to the host capsular exopolysaccharides (Probable). Displays a depolymerase activity that specifically degrades the K25-type polysaccharides of Klebsiella pneumoniae capsule (PubMed:28077636) PMID 28077636
Literature-linked bioRxiv
https://doi.org/10.1101/2025.09.09.675204
 literature_xref DepoCatalog: Mapping the Diversity of 105 Recombinant Klebsiella Phage Depolymerases Across Sequence, Structure, and Substrate Specificity PMID https://doi.org/10.1101/2025.09.09.675204

Rows marked “Validated by sequence identity” come from a different entry carrying the same sequence — the experiment was not performed on this protein.

Literature

Title Authors Date PMID Source
DepoCatalog: Mapping the Diversity of 105 Recombinant Klebsiella Phage Depolymerases Across Sequence, Structure, and Substrate Specificity DepoCatalog: Mapping the Diversity of 105 Recombinant Klebsiella Phage Depolymerases Across Sequence, Structure, and Substrate Specificity — https://doi.org/10.1101/2025.09.09.675204 bioRxiv