Protein

Validated by sequence identity RBP function shown
View in Explore
Genbank accession
GENB_ea75d787b0a7 [GenBank]
Protein name
tail fiber protein
RBP type
TSP
Evidence DepoScope
Probability 1,00
TF
Evidence GenBank
Probability 1,00
TSP
Evidence RBPdetect
Probability 0,85
TF
Evidence RBPdetect2
Probability 0,52
TF
Evidence UniProt/Swiss
Probability 1,00
TF
Evidence UniProt/TrEMBL
Probability 1,00
Seq2Symm
C3 confidence 0,978
C3 0,978
C1 0,315
D3 0,001
Predicted homo-oligomer symmetry (Seq2Symm, per-class probabilities; C1 = monomer, C2 = dimer, C3 = trimer).
Protein sequence
MADLKVGSTTGGSVIWHQGNFPLNPAGDDVLYKSFKIYSEYNKPQAADNDFVSKANGGTYASKVTFNAGIQVPYAPNIMSPCGIYGGNGDGATFDKANIDIVSWYGVGFKSSFGSTGRTVVINTRNGDINTKGVVSAAGQVRSGAAAPIAANDLTRKDYVDGAINTVTANANSRVLRSGDTMTGNLTAPNFFSQNPASQPSHVPRFDQIVIKDSVQDFGYY
Physico‐chemical
properties
protein length:221 AA
molecular weight: 23341,55310 Da
isoelectric point:7,77224
aromaticity:0,10407
hydropathy:-0,28597

Domains

View on InterPro
Domain architecture
GENB_ea75d787b0a7
1 221 aa
STR 56–195 ·
ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped
Proteins with similar domain architecture

Tail Spike Domain Segmentation

Segmented into three structural domains: N-terminal, central, and C-terminal.

Domain layout
GENB_ea75d787b0a7
1 221 aa
Domain Start End Length (AA) Confidence
N-terminal 1 77 77 0,6703
Central domain 78 210 134 0,1309
C-terminal 211 221 10 0,9522
N-terminal Central domain C-terminal

View these domains on the 3D structure via the Color by → Tail spike option in the Tertiary structure section below.

Taxonomy

Phage
Enterobacteria phage T4 [NCBI] · taxon 10665
Uroviricota Caudoviricetes Pantevenvirales Straboviridae Tequatrovirus Tequatrovirus T4
Host
Escherichia coli [NCBI] · taxon 562
Pseudomonadota Gammaproteobacteria Enterobacterales Enterobacteriaceae Escherichia Escherichia coli

Coding sequence (CDS)

Genbank protein accession
OZ035787.1_CDS_[59738..60403] [NCBI]
Genbank nucleotide accession
OZ035787.1 [NCBI]
CDS location
range 59738 -> 60403
strand +
CDS

  




        

        
      
    
  






  

  
  

    
Genome Context

  


  

    

      

    

  


  

  


  

  

  
  

  


  

    
Tertiary structure


  



  

    

      
        
          
            
              

                

                  
                  

                    

                      
GENB_ea75d787b0a7

                      
ESMFold structure

                    


                    

                      

                        Source
                        ESMFold
                      

                      
                      

                        
                          pLDDT
                          70.4
                        
                      

                      

                        Oligomeric state
                        monomer
                      

                    


                    

                      
                         Download structure
                      
                    


                    
                    

                    
                    

                  


                  
                  

                    

                      

                      
                    

                  

                


                
                

                
                
              

            
          
        
      

    

  








  
Experimental validation

  Validated by sequence identity





  

    
The evidence was produced on a different entry with an identical sequence. Strong, but the experiment was not done on this protein.

    

      

        
          

            Tier
            Source
            Assay
            Claim
            Reference
          

        
        
          
          

            Validated by sequence identity
            
              UniProt
              
P03743

            		
            
              ECO:0000269:FUNCTION:8709154
              
                RBP
              
            
            Structural component of the distal-half of the long-tail fiber. The long-tail fiber of T4 is about 1600 Angstroms long with a kink in the middle that divides the fiber into proximal and distal halves. The thin tip of the distal half-fiber interacts with the bacterial lipopolysaccharide receptor and specifies the host range of the phage
            
              
                PMID 8709154
              
            
          

          
          

            Validated by sequence identity
            
              UniProt
              
P03743

            		
            
              ECO:0000269:SUBUNIT:8709154
              
                RBP
              
            
            The long-tail fibers are trimeric, with a stoichiometry of gp34/gp37/gp36/gp35 of 3:3:3:1
            
              
                PMID 8709154
              
            
          

          
          

            Validated by sequence identity
            
              UniProt
              
P03743

            		
            
              protein_existence:evidence_at_protein_level
              
            
            1: Evidence at protein level
            
              
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      Rows marked “Validated by sequence identity” come from a different entry
      carrying the same sequence — the experiment was not performed on this protein.