Phage RBP Database

UniProt accession

A0AAU6PXW4 [UniProt]

Protein name

Tail tip protein

RBP type

TF

Evidence Phold

Probability 1,00

TSP

Evidence RBPdetect

Probability 0,88

TF

Evidence RBPdetect2

Probability 0,93

Seq2Symm

C3 confidence 0,865 truncated

C3	0,865
C1	0,020
D3	0,000

Predicted homo-oligomer symmetry (Seq2Symm, per-class probabilities; C1 = monomer, C2 = dimer, C3 = trimer).

Protein sequence

MIKNNVVTGRKGGSSKPHTPQEMEDNLISINKIKVLLAVSDGEVDANFSLKDLYLNDVPVIAPSGEVNYEGVKAEFRPGTQTQDYIKGFNDTAAEFTVGRELKTTTPYVISVTNKQLSAVRVKILMPRGVTTKENGDMVGVVVKWAVDMAVDGGSYQEVLLDTIDGKTLSGYDKTKRIDLPAFNSQVLLRVRRVTPDSTNSRVVDTINIQSYAEVIDAKFRYPLTGLVYVEFNSELFPQIPSISTKKKWKIINVPSNYDPVLREYSGTWDGSFKKAWSNNPAWVLYDLITNQRYGLDQRELGIAVDKWSLYDAGQYCDQKVPDGHGGLEPRYLCDVVIQSQVEAYNLVRDICSIFRGMSFWNGESLSIVIDRPREASYIFTNDNVVDGSFAYTFASEKSMYTTCNVTFDDEQNMYSQDIEGVFDLNASLRFGHNPTSITAIGCTRRSEANRRGRWVLKTNLRSTTVSFATGLEGMIPMIGDVVAIADNFWSSNLTLSLSGRVMEVSGLQVFTHFKVDARAGDFIIVNKPDGNPVRRTISKVSADGKTIELNVGFGFDVQPNTVFAIDRTDIALQQYVVTGITKGDGDDEFTYSITAVEYDQNKYDEIDYGVNIDDRPTSIVDPDNMQPPKNIVVSSYSRIVQGMSVETMVIGWGKVQYASKYDVQWRKDNGNWMNVPRTASSEVEVEGIYAGNYHVRVRSISSGGNTSPWSDVVSVGLTGKIGKPDKPTVITASDDQVFGIRVKLGFPEGSGDTAYTELQQIPDNGAGGHTGEENASLLTMIPYPQYEYWHSTLPAGYVNWYRARLVDRIGNASDWSDIVRGMSSDDVESIIGEIKVDIEGSEGFKYLQQNSIDSNVAIQAQAESILENALANDTDVRRMTKENGKRKAEYVQAVNLIADETQARVEALTQLKAQIDDEVVASITEVQTALATETEARTTADTVLSAQLGDTQAALNEKLDSWVDAESAGAQYGVKLGLKYNGVEYSAGMSMELVGSGAGVKSQLIFDASRFAISNGIGSGSGQWALPFVVESNQVFIQSAVIKDGSITNAKIGNRIQSNNYVAGSTGWAIDKSGSAEFSNATVRGNLYANSGNFAFNGTNNTVQINGNGITVNLANGGRVVVGTF

Physico‐chemical properties

protein length:	1126 AA
molecular weight:	123356,40030 Da
isoelectric point:	4,87056
aromaticity:	0,08881
hydropathy:	-0,28748

Domain architecture

A0AAU6PXW4

1 1126 aa

ATT 93–218 · ATT 340–502 · STR 627–722 · RBD 956–1094 ·

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

InterPro domains

IPR053171
Unmapped

IPR053171 Coil IPR015406

IPR055385
ATT

IPR055385 IPR032876 IPR013783

IPR003961
STR

IPR003961

IPR003961
STR

IPR003961

IPR036116
STR

IPR036116

A0AAU6PXW4

11126 aa

ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped

Novel HMM domains (de novo, PhaRBP-HMM)

Experimental de novo families on regions without InterPro annotation. Separate from the InterPro architecture above.

DC_0014
STR

DC_0014

A0AAU6PXW4

11126 aa

InterPro domain annotations

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
IPR053171	Unmapped	-	3	881	InterPro	Viral Tip Attachment Protein	-	-	-	-
IPR055385	ATT	DC_0360	93	218	InterPro cluster	Tip attachment protein J, HDII-ins2 domain	N-terminal	High	Text match	1136 proteins / 1139 hits
IPR032876	ATT	DC_0307	340	502	InterPro cluster	Tip attachment protein J	Central	Medium	Text match	1111 proteins / 1112 hits
IPR013783	STR	IPR013783	627	721	Merged direct domain	Immunoglobulin-like fold	Central	Low	Positional only	144 proteins / 144 hits
IPR003961	STR	DC_0003	628	716	InterPro cluster	Fibronectin type III	Central	High	Text match	998 proteins / 1603 hits
IPR003961	STR	DC_0003	628	722	InterPro cluster	Fibronectin type III	Central	High	Text match	998 proteins / 1603 hits
IPR036116	STR	IPR036116	628	716	Merged direct domain	Fibronectin type III superfamily	Central	Low	Positional only	52 proteins / 52 hits
Coil	Unmapped	-	899	919	Coils	Coil	-	-	-	-
IPR015406	RBD	DC_0135	956	1094	InterPro cluster	Tip attachment protein J, central straight fiber domain	C-terminal	High	Text match	1265 proteins / 1266 hits

Proteins with similar domain architecture

Segmented into three structural domains: N-terminal, central, and C-terminal.

Domain layout

A0AAU6PXW4

1 1126 aa

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	505	505	0,9066
Central domain	506	1058	554	0,0531
C-terminal	1059	1126	67	0,7558

Note: Constraints were applied during segmentation.
Fixed 38 C-terminal predictions appearing before Central domain

N-terminal Central domain C-terminal

View these domains on the 3D structure via the Color by → Tail spike option in the Tertiary structure section below.

Phage

Escherichia phage ETEP102 [NCBI] · taxon 3117680

Uroviricota Caudoviricetes Escherichia phage ETEP102

Host

Escherichia coli [NCBI] · taxon 562

Pseudomonadota Gammaproteobacteria Enterobacterales Enterobacteriaceae Escherichia Escherichia coli

No CDS data available.

Protein

Domains

Tail Spike Domain Segmentation

Taxonomy

Coding sequence (CDS)

Genome Context

Tertiary structure

Predicted Aligned Error (PAE)