Protein

Validated by sequence identity
View in Explore
UniProt accession
Q716G1 [UniProt]
Protein name
Tail spike protein
RBP type
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence GenBank
Probability 1,00
TSP
Evidence Phold
Probability 1,00
TSP
Evidence RBPdetect
Probability 0,91
TSP
Evidence RBPdetect2
Probability 0,97
TSP
Evidence UniProt/TrEMBL
Probability 1,00
Seq2Symm
C3 confidence 1,000
C3 1,000
C1 0,003
D2 0,001
Predicted homo-oligomer symmetry (Seq2Symm, per-class probabilities; C1 = monomer, C2 = dimer, C3 = trimer).
Protein sequence
MTDIITNVVIGMPSQLFTMARSFKAVANGKIYIGKIDTDPVNPENQIQVYVENEDGSHVPVSQPIVINAAGYPVYNGQIAKFVTEQGHSMAVYDAYGSQQFYFQNVLKYDPDQFGPDLIEQLAQSGKYSQDNTKGDAMIGVKQPLPKAVLRTQHDKNKEAISILDFGVIDDGVTDNYQAIQNAIDAVASLPSGGELFIPASNQAVGYIVGSTLLIPGGVNIRGVGKASQLRAKSGLTGSVLRLSYDSDTIGRYLRNIRVTGNNTCNGIDTNITAEDSVIRQVYGWVFDNVMVNEVETAYLMQGLWHSKFIACQAGTCRVGLHFLGQCVSVSVSSCHFSRGNYSADESFGIRIQPQTYAWSSEAVRSEAIILDSETMCIGFKNAVYVHDCLDLHMEQLDLDYCGSTGVVIENVNGGFSFSNSWIAADADGTEQFTGIYFRTPTSTQSHKIVSGVHINTANKNTAANNQSIAIEQSAIFVFVSGCTLTGDEWAVNIVDINECVSFDKCIFNKPLRYLRSGGVSVTDCYLAGITEVQKPEGRYNTYRGCSGVPSVNGIINVPVAVGATSGSAAIPNPGNLTYRVRSLFGDPASSGDKVSVSGVTINVTRPSPVGVALPSMVEYLAI
Physico‐chemical
properties
protein length:623 AA
molecular weight: 67065,69120 Da
isoelectric point:5,09513
aromaticity:0,08668
hydropathy:-0,03435

Domains

View on InterPro
Domain architecture
Q716G1
1 623 aa
ATT 1–113 · STR 114–623
ATT Attachment Domain STR Structural Domain RBD Receptor-Binding Domain CBM Carbohydrate-Binding Module LEC Lectin-like Domain ENZ Enzymatic Domain CHP Intramolecular Chaperone LNK Linker/Spacer Domain TAS Tail-Associated Structural TTP Tail Tubular Protein UNK Uncharacterized Domain Unmapped
Proteins with similar domain architecture

Tail Spike Domain Segmentation

Segmented into three structural domains: N-terminal, central, and C-terminal.

Domain layout
Q716G1
1 623 aa
Domain Start End Length (AA) Confidence
N-terminal 1 175 175 0,9908
Central domain 176 549 375 0,9924
C-terminal 550 623 73 0,9791
N-terminal Central domain C-terminal

View these domains on the 3D structure via the Color by → Tail spike option in the Tertiary structure section below.

Taxonomy

Phage
Shigella phage Sf6 [NCBI] · taxon 10761
Uroviricota Caudoviricetes Lederbergvirus
Host
Shigella flexneri [NCBI] · taxon 623
cellular organisms Bacteria Pseudomonadati Pseudomonadota Gammaproteobacteria Enterobacterales

Coding sequence (CDS)

Genbank protein accession
AAQ12204.1 [NCBI]
Genbank nucleotide accession
AF547987 [NCBI]
CDS location
range 13719 -> 15590
strand +
CDS
ATGACAGACATTATAACCAATGTTGTAATTGGGATGCCTTCGCAACTCTTCACTATGGCTCGTTCTTTTAAAGCCGTAGCCAATGGCAAAATTTATATCGGTAAAATTGACACTGACCCGGTAAATCCTGAAAACCAGATTCAGGTTTATGTAGAGAATGAAGACGGATCTCACGTCCCTGTTTCTCAGCCAATTGTTATCAATGCTGCCGGATATCCTGTGTACAACGGGCAGATTGCCAAATTTGTAACTGAGCAAGGCCATTCAATGGCTGTATATGATGCGTATGGTTCGCAGCAGTTCTATTTTCAGAATGTGCTGAAGTACGACCCTGATCAGTTCGGTCCGGATTTAATTGAGCAACTAGCTCAATCCGGTAAGTATTCGCAGGATAACACCAAAGGCGATGCCATGATTGGCGTCAAGCAGCCTTTACCAAAAGCAGTTTTAAGAACTCAGCATGACAAAAATAAAGAAGCAATAAGTATCCTGGATTTTGGTGTTATTGATGATGGTGTGACAGATAATTACCAGGCAATACAAAATGCAATAGATGCCGTTGCTTCACTACCCTCCGGCGGGGAGCTGTTTATCCCTGCGAGCAACCAAGCGGTTGGGTATATTGTTGGATCCACTTTGCTTATTCCTGGCGGTGTTAACATCAGAGGGGTTGGTAAGGCATCGCAACTCCGAGCAAAAAGCGGACTTACAGGATCTGTGTTAAGGCTGTCTTATGATTCAGACACTATCGGCCGTTATCTGAGAAATATACGAGTAACTGGTAATAACACCTGCAATGGTATTGACACAAACATTACAGCAGAAGACTCTGTCATCAGACAGGTTTATGGCTGGGTATTTGATAATGTAATGGTGAATGAAGTTGAAACCGCTTATTTAATGCAAGGGCTCTGGCACTCAAAATTTATAGCATGTCAGGCTGGAACCTGTAGAGTCGGTCTTCACTTTTTAGGCCAGTGCGTAAGTGTTAGTGTCAGCTCCTGCCATTTCAGCAGAGGAAATTATTCTGCTGATGAAAGCTTTGGCATCAGGATTCAGCCTCAAACGTATGCGTGGTCGTCAGAGGCAGTTAGGTCAGAAGCAATAATTTTAGACAGTGAGACCATGTGCATTGGTTTTAAAAATGCCGTCTATGTTCATGATTGCCTTGATTTGCATATGGAACAACTGGATTTAGATTATTGCGGCTCAACAGGCGTGGTTATAGAGAATGTAAACGGAGGATTTTCTTTCTCAAACTCATGGATAGCAGCAGATGCCGATGGCACTGAACAATTTACGGGGATATATTTTAGAACGCCGACCTCAACGCAGTCACATAAAATTGTCAGTGGTGTTCATATCAACACTGCAAACAAAAACACGGCTGCAAACAATCAAAGTATAGCGATAGAACAGTCGGCGATCTTCGTCTTTGTAAGTGGTTGTACGTTAACTGGTGATGAATGGGCTGTAAATATTGTCGACATCAATGAATGTGTTTCTTTCGATAAGTGCATATTCAATAAGCCTCTACGCTATCTTCGTAGCGGTGGCGTGTCAGTTACTGACTGTTATTTGGCTGGCATTACCGAGGTGCAGAAACCGGAAGGCAGATACAATACGTATCGTGGCTGTTCAGGCGTACCGTCTGTAAATGGGATCATTAATGTCCCAGTTGCGGTAGGTGCCACAAGCGGATCTGCAGCTATACCGAACCCGGGGAACCTGACATACAGAGTAAGAAGCCTTTTTGGTGACCCTGCATCAAGTGGTGACAAGGTTAGTGTTTCCGGGGTGACAATTAATGTTACTCGCCCAAGCCCAGTAGGAGTCGCGCTGCCTTCAATGGTTGAGTATCTGGCCATCTGA

Genome Context

Gene Ontology

Description Category Evidence (source)
GO:0098024 virus tail, fiber Cellular Component IEA:UniProtKB-KW (UniProt)
GO:0052775 endo-1,3-alpha-L-rhamnosidase activity Molecular Function IEA:UniProtKB-ARBA (UniProt)
GO:0098994 symbiont entry into host cell via disruption of host cell envelope Biological Process IEA:UniProtKB-KW (UniProt)
GO:0098995 symbiont entry into host cell via disruption of host cell envelope lipopolysaccharide Biological Process IEA:UniProtKB-KW (UniProt)
GO:0019062 virion attachment to host cell Biological Process IEA:UniProtKB-KW (UniProt)

Tertiary structure

Q716G1
ESMFold structure
Source ESMFold
pLDDT 83.2
Oligomeric state monomer
Download structure

Experimental validation

Validated by sequence identity

The evidence was produced on a different entry with an identical sequence. Strong, but the experiment was not done on this protein.

Tier Source Assay Claim Reference
Validated by sequence identity GenBank
AAQ12204.1
 experiment:unspecified gene 14 protein – experimental evidence, no additional details recorded —
Validated by sequence identity GenBank
NP_958190.1
 experiment:unspecified tail spike protein – experimental evidence, no additional details recorded —
Literature-linked PubMed
15136040
 literature_xref — PMID 15136040

Rows marked “Validated by sequence identity” come from a different entry carrying the same sequence — the experiment was not performed on this protein.

Literature

Title Authors Date PMID Source
— — 15136040 PubMed